ZA200807590B - Diagnostics and treatments for tumors - Google Patents

Diagnostics and treatments for tumors

Info

Publication number
ZA200807590B
ZA200807590B ZA200807590A ZA200807590A ZA200807590B ZA 200807590 B ZA200807590 B ZA 200807590B ZA 200807590 A ZA200807590 A ZA 200807590A ZA 200807590 A ZA200807590 A ZA 200807590A ZA 200807590 B ZA200807590 B ZA 200807590B
Authority
ZA
South Africa
Prior art keywords
diagnostics
tumors
treatments
Prior art date
Application number
ZA200807590A
Other languages
English (en)
Inventor
Baldwin Megan
Ferrara Napoleone
Gerber Hans-Peter
Shojaei Farbod
Zhong Cuiling
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA200807590B publication Critical patent/ZA200807590B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
ZA200807590A 2006-03-29 2007-03-28 Diagnostics and treatments for tumors ZA200807590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78772006P 2006-03-29 2006-03-29

Publications (1)

Publication Number Publication Date
ZA200807590B true ZA200807590B (en) 2009-11-25

Family

ID=38564192

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807590A ZA200807590B (en) 2006-03-29 2007-03-28 Diagnostics and treatments for tumors

Country Status (19)

Country Link
US (2) US20070264193A1 (no)
EP (1) EP1999151A2 (no)
JP (1) JP2009531463A (no)
KR (1) KR20080106946A (no)
CN (1) CN101448856A (no)
AR (1) AR060228A1 (no)
AU (1) AU2007233237A1 (no)
BR (1) BRPI0709425A2 (no)
CA (1) CA2647430A1 (no)
CL (1) CL2007000876A1 (no)
CR (1) CR10325A (no)
IL (1) IL193842A0 (no)
MA (1) MA30348B1 (no)
MX (1) MX2008012279A (no)
NO (1) NO20084546L (no)
RU (1) RU2008142775A (no)
TW (1) TW200806322A (no)
WO (1) WO2007115045A2 (no)
ZA (1) ZA200807590B (no)

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DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US20100196509A1 (en) 2005-02-28 2010-08-05 Jonathan Braun Methods for Diagnosis and Treatment of Endometrial Cancer
US8318906B2 (en) 2005-04-15 2012-11-27 The Regents Of The University Of California EMP2 antibodies and their therapeutic uses
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
JP2010518839A (ja) * 2007-02-21 2010-06-03 アブリンクス エン.ヴェー. 血管内皮増殖因子に指向性を有するアミノ酸配列、及び過度の及び/もしくは病的な血管形成又は血管新生を特徴とする症状及び疾患を治療するためにこれを含むポリペプチド
WO2009067546A2 (en) * 2007-11-19 2009-05-28 Celera Corpration Lung cancer markers and uses thereof
WO2009075768A2 (en) * 2007-12-07 2009-06-18 Children's Hospital Of Orange County Optical device and method for real-time chemosensitivity testing
EP2649995A3 (en) * 2008-02-29 2014-05-21 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of post-radiation tumor growth
WO2010017083A1 (en) * 2008-08-04 2010-02-11 Wayne State University Methods of treating cancer with cd11b antibodies
CN102137939A (zh) * 2008-08-29 2011-07-27 霍夫曼-拉罗奇有限公司 不依赖vegf的肿瘤的诊断和治疗
US20110190380A1 (en) * 2008-10-23 2011-08-04 Elena Feinstein Methods for delivery of sirna to bone marrow cells and uses thereof
US9498431B2 (en) 2008-12-10 2016-11-22 Jianjian Xu Controlled releasing composition
KR20160021308A (ko) * 2008-12-23 2016-02-24 제넨테크, 인크. 암 환자에서의 진단 목적용 방법 및 조성물
US7615353B1 (en) 2009-07-06 2009-11-10 Aveo Pharmaceuticals, Inc. Tivozanib response prediction
MX2012001306A (es) * 2009-07-31 2012-02-28 Genentech Inc Inhibicion de matastasis de tumor.
MX2012001716A (es) * 2009-08-14 2012-04-02 Genentech Inc Marcadores biologicos para monitorizar la respuesta del paciente a los antagonistas vegf.
US7736861B1 (en) 2009-10-19 2010-06-15 Aveo Pharmaceuticals, Inc. Tivozanib response prediction
EP2501409A4 (en) 2009-11-20 2015-02-18 Univ California EPITHELIAL MEMBRANE PROTEIN 2 (EMP2) AND PROLIFERATIVE VITREORETINOPATHY (PVR)
US9375473B2 (en) 2010-02-19 2016-06-28 Cornell Research Foundation, Inc. Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases
JP5852968B2 (ja) * 2010-02-19 2016-02-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 上皮膜タンパク質2(emp2)結合試薬および眼疾患治療におけるその使用
KR101313184B1 (ko) * 2010-06-24 2013-09-30 한국표준과학연구원 질병 지표 검출 키트 및 질병 지표 검출 방법
EP2744825A1 (en) * 2011-08-17 2014-06-25 F.Hoffmann-La Roche Ag Inhibition of angiogenesis in refractory tumors
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
RU2502471C9 (ru) * 2012-08-21 2015-04-20 Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") Способ оценки соответствия размеров селезенки норме или отклонению от нее у детей методом ультразвуковой диагностики
EP2741086A1 (en) * 2012-12-06 2014-06-11 Ludwig Boltzmann Gesellschaft Method for measuring coagulation of blood samples using viscoelastic tests (VET)
WO2014127785A1 (en) * 2013-02-20 2014-08-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014159923A1 (en) * 2013-03-13 2014-10-02 Health Research, Inc. Enhancement of vaccines
RU2546105C1 (ru) * 2014-04-29 2015-04-10 Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") Способ оценки методом ультразвуковой диагностики соответствия размеров селезенки норме или отклонению от нее у детей от 3 до 15 лет
WO2018078158A1 (en) * 2016-10-31 2018-05-03 Hexal Ag Antibody preparation
WO2020023183A1 (en) * 2018-07-24 2020-01-30 So Young Life Sciences Corporation Use of liposomes to deliver a protein and a gene encoding the protein to a live cell
US20200347449A1 (en) * 2019-05-01 2020-11-05 The Broad Institute, Inc. Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
CN112946291A (zh) * 2019-12-10 2021-06-11 上海交通大学医学院附属仁济医院 Fgf18在制备诊断和预测卵巢癌试剂中的应用及fgf18化学发光检测试剂盒

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US4840793A (en) * 1987-06-11 1989-06-20 Dana-Farber Cancer Institute Method of reducing tissue damage at an inflammatory site using a monoclonal antibody
US20030206899A1 (en) * 1991-03-29 2003-11-06 Genentech, Inc. Vascular endothelial cell growth factor antagonists
US20020032313A1 (en) * 1991-03-29 2002-03-14 Genentech, Inc. Vascular endothelial cell growth factor antagonists
US6582959B2 (en) * 1991-03-29 2003-06-24 Genentech, Inc. Antibodies to vascular endothelial cell growth factor
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
DE4422551C1 (de) * 1994-06-28 1995-07-27 Daimler Benz Ag Durch Servomotor unterstützte Zahnstangenlenkung
US5871697A (en) * 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
DK0973804T3 (da) * 1997-04-07 2007-05-07 Genentech Inc Anti-VEGF-antistoffer
US6884879B1 (en) * 1997-04-07 2005-04-26 Genentech, Inc. Anti-VEGF antibodies
US20020032315A1 (en) * 1997-08-06 2002-03-14 Manuel Baca Anti-vegf antibodies
EP1187633A4 (en) * 1999-04-08 2005-05-11 Arch Dev Corp USE OF ANTI-VEGF ANTIBODY FOR INCREASING IRRADIATION IN CANCER THERAPY
US6703020B1 (en) * 1999-04-28 2004-03-09 Board Of Regents, The University Of Texas System Antibody conjugate methods for selectively inhibiting VEGF
BR0111861A (pt) * 2000-06-23 2003-12-23 Schering Ag Combinações e composições que interferem com função receptora vegf/vegf e angiopoietina/tie e seu uso(ii)
WO2003068155A2 (en) * 2002-02-12 2003-08-21 Vanderbilt University Inhibition of vegf receptor signaling reverses tumor resistance to radiotherapy
MXPA05012723A (es) * 2003-05-30 2006-02-08 Genentech Inc Tratamiento con anticuerpos anti-vgf.
WO2005044853A2 (en) * 2003-11-01 2005-05-19 Genentech, Inc. Anti-vegf antibodies
US20060009360A1 (en) * 2004-06-25 2006-01-12 Robert Pifer New adjuvant composition

Also Published As

Publication number Publication date
IL193842A0 (en) 2011-08-01
AU2007233237A1 (en) 2007-10-11
CR10325A (es) 2008-12-03
AR060228A1 (es) 2008-06-04
WO2007115045A2 (en) 2007-10-11
RU2008142775A (ru) 2010-05-10
MA30348B1 (fr) 2009-04-01
TW200806322A (en) 2008-02-01
BRPI0709425A2 (pt) 2011-07-12
MX2008012279A (es) 2008-10-08
EP1999151A2 (en) 2008-12-10
NO20084546L (no) 2008-12-23
US20100239568A1 (en) 2010-09-23
CL2007000876A1 (es) 2008-02-08
US20070264193A1 (en) 2007-11-15
CA2647430A1 (en) 2007-10-11
WO2007115045A3 (en) 2008-04-03
KR20080106946A (ko) 2008-12-09
CN101448856A (zh) 2009-06-03
JP2009531463A (ja) 2009-09-03

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