ZA200807054B - N-formyl hydroxylamine compounds - Google Patents
N-formyl hydroxylamine compoundsInfo
- Publication number
- ZA200807054B ZA200807054B ZA200807054A ZA200807054A ZA200807054B ZA 200807054 B ZA200807054 B ZA 200807054B ZA 200807054 A ZA200807054 A ZA 200807054A ZA 200807054 A ZA200807054 A ZA 200807054A ZA 200807054 B ZA200807054 B ZA 200807054B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxylamine compounds
- formyl hydroxylamine
- formyl
- compounds
- hydroxylamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77937706P | 2006-03-03 | 2006-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200807054B true ZA200807054B (en) | 2009-10-28 |
Family
ID=38510154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200807054A ZA200807054B (en) | 2006-03-03 | 2008-08-15 | N-formyl hydroxylamine compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090062537A1 (xx) |
| EP (1) | EP1994027A2 (xx) |
| JP (1) | JP2009529008A (xx) |
| KR (1) | KR20080095895A (xx) |
| CN (1) | CN101395148A (xx) |
| AU (1) | AU2007226715A1 (xx) |
| BR (1) | BRPI0708524A2 (xx) |
| CA (1) | CA2643267A1 (xx) |
| CR (1) | CR10251A (xx) |
| EC (1) | ECSP088712A (xx) |
| GT (1) | GT200800170A (xx) |
| IL (1) | IL193524A0 (xx) |
| MA (1) | MA30285B1 (xx) |
| MX (1) | MX2008011128A (xx) |
| NO (1) | NO20084069L (xx) |
| RU (1) | RU2008139192A (xx) |
| TN (1) | TNSN08344A1 (xx) |
| WO (1) | WO2007106670A2 (xx) |
| ZA (1) | ZA200807054B (xx) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584694B (zh) * | 2009-06-15 | 2011-01-12 | 华东师范大学 | 含2,5-二氢吡咯的肽脱甲酰基酶抑制剂及合成方法 |
| CN101869563B (zh) * | 2010-07-02 | 2011-11-16 | 华东师范大学 | 含4-亚甲基吡咯烷的肽脱甲酰基酶抑制剂 |
| AR085698A1 (es) * | 2011-03-09 | 2013-10-23 | Glaxosmithkline Llc | Inhibidores de la peptido desformilasa |
| CN103159660B (zh) * | 2011-12-08 | 2016-07-06 | 天津市国际生物医药联合研究院 | (2r)-1-(2-甲基-3-(甲氧基(甲基)氨基)-丙酰基)吡咯烷-2-羧酸及其应用 |
| WO2013106646A2 (en) * | 2012-01-12 | 2013-07-18 | Yale University | Compounds and methods for the inhibition of vcb e3 ubiquitin ligase |
| EP3608317A1 (en) | 2012-01-12 | 2020-02-12 | Yale University | Compounds & methods for the enhanced degradation of targeted proteins & other polypeptides by an e3 ubiquitin ligase |
| RU2014137052A (ru) | 2012-02-24 | 2016-04-10 | Ф.Хоффманн-Ля Рош Аг | Противовирусные соединения |
| GB201311888D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| GB201311891D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| AU2015213900B2 (en) * | 2014-02-06 | 2018-12-13 | Nxera Pharma Uk Limited | Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor agonists |
| US10071164B2 (en) | 2014-08-11 | 2018-09-11 | Yale University | Estrogen-related receptor alpha based protac compounds and associated methods of use |
| JP6817962B2 (ja) | 2015-01-20 | 2021-01-20 | アルビナス・オペレーションズ・インコーポレイテッドＡｒｖｉｎａｓ Ｏｐｅｒａｔｉｏｎｓ， Ｉｎｃ． | ターゲティングされたアンドロゲン受容体分解のための化合物および方法 |
| US20170327469A1 (en) | 2015-01-20 | 2017-11-16 | Arvinas, Inc. | Compounds and methods for the targeted degradation of androgen receptor |
| CN108601764A (zh) | 2015-03-18 | 2018-09-28 | 阿尔维纳斯股份有限公司 | 用于靶蛋白的增强降解的化合物和方法 |
| EP3302482A4 (en) | 2015-06-05 | 2018-12-19 | Arvinas, Inc. | Tank-binding kinase-1 protacs and associated methods of use |
| WO2017030814A1 (en) | 2015-08-19 | 2017-02-23 | Arvinas, Inc. | Compounds and methods for the targeted degradation of bromodomain-containing proteins |
| AU2016349781A1 (en) | 2015-11-02 | 2018-05-10 | Yale University | Proteolysis targeting chimera compounds and methods of preparing and using same |
| US20180072711A1 (en) | 2016-09-15 | 2018-03-15 | Arvinas, Inc. | Indole derivatives as estrogen receptor degraders |
| PL3660004T3 (pl) | 2016-10-11 | 2023-10-02 | Arvinas Operations, Inc. | Związki i sposoby do ukierunkowanej degradacji receptora androgenowego |
| CN110234646A (zh) | 2016-11-01 | 2019-09-13 | 阿尔维纳斯股份有限公司 | 靶向PROTAC的Tau蛋白及相关使用方法 |
| US10647698B2 (en) | 2016-12-01 | 2020-05-12 | Arvinas Operations, Inc. | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders |
| US11173211B2 (en) | 2016-12-23 | 2021-11-16 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides |
| EP3558994A4 (en) | 2016-12-23 | 2021-05-12 | Arvinas Operations, Inc. | COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES |
| JP2020505327A (ja) | 2016-12-23 | 2020-02-20 | アルビナス・オペレーションズ・インコーポレイテッドＡｒｖｉｎａｓ Ｏｐｅｒａｔｉｏｎｓ， Ｉｎｃ． | Ｅｇｆｒタンパク質分解標的化キメラ分子およびその関連する使用方法 |
| US10806737B2 (en) | 2016-12-23 | 2020-10-20 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of fetal liver kinase polypeptides |
| US11191741B2 (en) | 2016-12-24 | 2021-12-07 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide |
| AU2018211975B2 (en) | 2017-01-26 | 2022-05-26 | Arvinas Operations, Inc. | Modulators of estrogen receptor proteolysis and associated methods of use |
| EP3710443A1 (en) | 2017-11-17 | 2020-09-23 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides |
| US11220515B2 (en) | 2018-01-26 | 2022-01-11 | Yale University | Imide-based modulators of proteolysis and associated methods of use |
| KR20240095318A (ko) | 2018-04-04 | 2024-06-25 | 아비나스 오퍼레이션스, 인코포레이티드 | 단백질분해 조절제 및 연관된 사용 방법 |
| JP7297053B2 (ja) | 2018-08-20 | 2023-06-23 | アルビナス・オペレーションズ・インコーポレイテッド | 神経変性疾患を治療するためのｅ３ユビキチンリガーゼ結合活性を有するキメラ（ｐｒｏｔａｃ）化合物を標的とし、アルファ－シヌクレインタンパク質を標的とするタンパク質分解 |
| JP7548992B2 (ja) | 2019-07-17 | 2024-09-10 | アルビナス・オペレーションズ・インコーポレイテッド | タウタンパク質標的化化合物および関連する使用方法 |
| TW202136240A (zh) | 2019-12-19 | 2021-10-01 | 美商亞文納營運公司 | 用於靶向降解雄激素受體之化合物及方法 |
| CA3181782A1 (en) | 2020-05-09 | 2021-11-18 | Arvinas Operations, Inc. | Methods of manufacturing a bifunctional compound, ultrapure forms of the bifunctional compound, and dosage forms comprising the same |
| CN117279910A (zh) | 2021-04-16 | 2023-12-22 | 阿尔维纳斯运营股份有限公司 | Bcl6蛋白水解的调节剂和其相关使用方法 |
| US11957759B1 (en) | 2022-09-07 | 2024-04-16 | Arvinas Operations, Inc. | Rapidly accelerated fibrosarcoma (RAF) degrading compounds and associated methods of use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR036053A1 (es) * | 2001-06-15 | 2004-08-04 | Versicor Inc | Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas |
| EP1599440A2 (en) * | 2003-02-21 | 2005-11-30 | Novartis AG | Chemical process for the preparation of intermediates to obtain n-formyl hydroxylamine compounds |
-
2007
- 2007-03-02 KR KR1020087021464A patent/KR20080095895A/ko not_active Application Discontinuation
- 2007-03-02 WO PCT/US2007/063167 patent/WO2007106670A2/en active Application Filing
- 2007-03-02 MX MX2008011128A patent/MX2008011128A/es not_active Application Discontinuation
- 2007-03-02 CN CNA2007800077069A patent/CN101395148A/zh active Pending
- 2007-03-02 BR BRPI0708524-9A patent/BRPI0708524A2/pt not_active IP Right Cessation
- 2007-03-02 JP JP2008557514A patent/JP2009529008A/ja active Pending
- 2007-03-02 AU AU2007226715A patent/AU2007226715A1/en not_active Abandoned
- 2007-03-02 EP EP07757788A patent/EP1994027A2/en not_active Withdrawn
- 2007-03-02 RU RU2008139192/04A patent/RU2008139192A/ru not_active Application Discontinuation
- 2007-03-02 CA CA002643267A patent/CA2643267A1/en not_active Abandoned
- 2007-03-02 US US12/280,896 patent/US20090062537A1/en not_active Abandoned
-
2008
- 2008-08-15 ZA ZA200807054A patent/ZA200807054B/xx unknown
- 2008-08-18 IL IL193524A patent/IL193524A0/en unknown
- 2008-08-26 CR CR10251A patent/CR10251A/es unknown
- 2008-09-02 GT GT200800170A patent/GT200800170A/es unknown
- 2008-09-02 TN TNP2008000344A patent/TNSN08344A1/en unknown
- 2008-09-02 EC EC2008008712A patent/ECSP088712A/es unknown
- 2008-09-17 MA MA31247A patent/MA30285B1/fr unknown
- 2008-09-24 NO NO20084069A patent/NO20084069L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101395148A (zh) | 2009-03-25 |
| MA30285B1 (fr) | 2009-03-02 |
| IL193524A0 (en) | 2009-08-03 |
| NO20084069L (no) | 2008-12-03 |
| CR10251A (es) | 2008-10-27 |
| TNSN08344A1 (en) | 2009-12-29 |
| JP2009529008A (ja) | 2009-08-13 |
| WO2007106670A3 (en) | 2008-01-24 |
| MX2008011128A (es) | 2008-09-08 |
| RU2008139192A (ru) | 2010-04-10 |
| WO2007106670A2 (en) | 2007-09-20 |
| CA2643267A1 (en) | 2007-09-20 |
| BRPI0708524A2 (pt) | 2011-05-31 |
| ECSP088712A (es) | 2008-10-31 |
| EP1994027A2 (en) | 2008-11-26 |
| US20090062537A1 (en) | 2009-03-05 |
| KR20080095895A (ko) | 2008-10-29 |
| AU2007226715A1 (en) | 2007-09-20 |
| GT200800170A (es) | 2008-10-29 |
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