ZA200806497B - Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids - Google Patents
Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acidsInfo
- Publication number
- ZA200806497B ZA200806497B ZA2008/06497A ZA200806497A ZA200806497B ZA 200806497 B ZA200806497 B ZA 200806497B ZA 2008/06497 A ZA2008/06497 A ZA 2008/06497A ZA 200806497 A ZA200806497 A ZA 200806497A ZA 200806497 B ZA200806497 B ZA 200806497B
- Authority
- ZA
- South Africa
- Prior art keywords
- drug delivery
- organic acids
- delivery systems
- blocking agent
- weakly basic
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 2
- 239000002981 blocking agent Substances 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 150000007524 organic acids Chemical class 0.000 title 1
- 235000005985 organic acids Nutrition 0.000 title 1
- 229940076279 serotonin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76275006P | 2006-01-27 | 2006-01-27 | |
| PCT/US2007/061217 WO2007090082A2 (en) | 2006-01-27 | 2007-01-29 | Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200806497B true ZA200806497B (en) | 2009-12-30 |
Family
ID=38325269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2008/06497A ZA200806497B (en) | 2006-01-27 | 2008-07-25 | Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070190145A1 (enExample) |
| EP (2) | EP1976491B1 (enExample) |
| JP (3) | JP5433236B2 (enExample) |
| KR (1) | KR101413613B1 (enExample) |
| CN (2) | CN101410094B (enExample) |
| AU (1) | AU2007211091B8 (enExample) |
| BR (1) | BRPI0707324A2 (enExample) |
| CA (1) | CA2640460C (enExample) |
| ES (2) | ES2550035T3 (enExample) |
| IL (1) | IL193020A0 (enExample) |
| NZ (1) | NZ570039A (enExample) |
| RU (1) | RU2490012C2 (enExample) |
| WO (1) | WO2007090082A2 (enExample) |
| ZA (1) | ZA200806497B (enExample) |
Families Citing this family (36)
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|---|---|---|---|---|
| KR101489401B1 (ko) * | 2006-01-27 | 2015-02-03 | 앱탈리스 파마테크, 인코포레이티드 | 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템 |
| CN105534936B (zh) * | 2007-08-13 | 2020-07-31 | Ohemo 生命科学股份有限公司 | 抗滥用药物、使用方法和制备方法 |
| WO2009076361A1 (en) * | 2007-12-10 | 2009-06-18 | Eurand, Inc. | Orally disintegrating tablets comprising diphenhydramine |
| WO2009086046A1 (en) * | 2007-12-21 | 2009-07-09 | Eurand, Inc. | Orally disintegrating tablet compositions of temazepam |
| JP5783725B2 (ja) | 2007-12-28 | 2015-09-24 | インパックス ラボラトリーズ、 インコーポレイテッドImpax Laboratories, Inc. | レボドパの放出制御製剤及びその使用 |
| EP2090297A1 (en) * | 2008-02-13 | 2009-08-19 | Boehringer Ingelheim International GmbH | Formulations of flibanserin |
| US8133506B2 (en) * | 2008-03-12 | 2012-03-13 | Aptalis Pharmatech, Inc. | Drug delivery systems comprising weakly basic drugs and organic acids |
| TWI519322B (zh) * | 2008-04-15 | 2016-02-01 | 愛戴爾製藥股份有限公司 | 包含弱鹼性藥物及控制釋放劑型之組合物 |
| WO2010026993A1 (ja) * | 2008-09-03 | 2010-03-11 | 武田薬品工業株式会社 | 製剤における吸収性改善方法および吸収性が改善された製剤 |
| US20120128764A1 (en) * | 2009-02-23 | 2012-05-24 | Aptalis Pharmatech, Inc. | Controlled-release compositions comprising a proton pump inhibitor |
| RU2011145278A (ru) * | 2009-04-09 | 2013-05-20 | Алкермес Фарма Айэленд Лимитед | Композиции клозапина с контролируемым высвобождением |
| US20110003005A1 (en) * | 2009-07-06 | 2011-01-06 | Gopi Venkatesh | Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions |
| BR112012013011A2 (pt) * | 2009-11-30 | 2015-09-08 | Aptalis Pharmatech Inc | odt; composição de odt; método para a preparação de um tablete de odt multiparticulado, método para tratar ou prevenir náusea e vômito pós operatória ou náusea e vômito pós- alta por até 24 horas após a dosagem, método para tratar pu prevenir náusea por até 24 horas após a dosagem e método para tratar ou prevenir náusea e vômito associados a radioterapia em pacientes que recebem ou irradiação de corpo total, dose alta única ao abdômen, ou frações diárias ao abdômen por até 24 horas após a dosagem |
| MX337603B (es) | 2009-11-30 | 2016-03-10 | Adare Pharmaceuticals Inc | Composiciones y tabletas farmaceuticas con recubrimiento compresible y metodos de fabricacion. |
| KR101143997B1 (ko) * | 2010-03-04 | 2012-05-09 | 한미사이언스 주식회사 | 유산균 제제 및 5-ht4 수용체 효능제를 함유하는 경구 투여용 복합 제제 및 이의 제조방법 |
| GB201004020D0 (en) | 2010-03-11 | 2010-04-21 | Acacia Pharma Ltd | New therapeutic use |
| US9011912B2 (en) | 2010-10-07 | 2015-04-21 | Abon Pharmaceuticals, Llc | Extended-release oral dosage forms for poorly soluble amine drugs |
| CN107028900A (zh) | 2010-12-02 | 2017-08-11 | 艾戴尔医药公司 | 快速分散颗粒、口腔崩解片以及方法 |
| US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
| EP3782614A1 (en) | 2013-10-07 | 2021-02-24 | Impax Laboratories, LLC | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
| SG10201808645TA (en) * | 2013-12-16 | 2018-11-29 | Massachusetts Inst Technology | Fortified Micronutrient Salt Formulations |
| CN106456611B (zh) | 2014-03-11 | 2021-07-20 | 红山生物医药有限公司 | 用于治疗恶心、呕吐或腹泻症状的恩丹西酮缓释固体制剂 |
| PL3200764T3 (pl) * | 2014-10-01 | 2020-12-28 | Oxytone Bioscience B.V. | Rozpadająca się w jamie ustnej stała farmaceutyczna jednostka dawkowania zawierająca substancję kontrolującą poród |
| ES2690140T3 (es) * | 2014-10-01 | 2018-11-19 | Oxytone Bioscience B.V. | Unidad de dosificación farmacéutica sólida de desintegración oral que contiene una sustancia de control del parto |
| CN104473895A (zh) * | 2014-11-20 | 2015-04-01 | 美吉斯制药(厦门)有限公司 | 拉莫三嗪口腔崩解缓释片 |
| US10406336B2 (en) * | 2016-08-03 | 2019-09-10 | Neil S. Davey | Adjustable rate drug delivery implantable device |
| GB201702250D0 (en) | 2017-02-10 | 2017-03-29 | Acacia Pharma Ltd | Method |
| CN108624005B (zh) * | 2017-03-24 | 2021-10-29 | 华东理工大学 | 基于poc和介孔纳米微球的双因子缓释系统 |
| EP4167971A1 (en) | 2020-06-18 | 2023-04-26 | XWPharma Ltd. | Controlled release granulations of water-soluble active pharmaceutical ingredients |
| WO2022020621A1 (en) | 2020-07-24 | 2022-01-27 | XWPharma Ltd. | Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative |
| EP4225274A1 (en) | 2020-10-05 | 2023-08-16 | XWPharma Ltd. | Modified release compositions of a gamma-hydroxybutyric acid derivative |
| WO2022140448A1 (en) | 2020-12-22 | 2022-06-30 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
| US11986449B2 (en) | 2020-12-22 | 2024-05-21 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
| DK4308086T3 (da) | 2021-03-19 | 2025-11-17 | Xwpharma Ltd | Farmakokinetik af formuleringer med kombineret frigivelse af et gamma-hydroxysmørsyrederivat |
| WO2022233885A2 (en) * | 2021-05-03 | 2022-11-10 | Cambridge Glycoscience Ltd | Soluble and insoluble saccharide compositions and related methods |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
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| US8133506B2 (en) * | 2008-03-12 | 2012-03-13 | Aptalis Pharmatech, Inc. | Drug delivery systems comprising weakly basic drugs and organic acids |
-
2007
- 2007-01-29 CN CN2007800114852A patent/CN101410094B/zh not_active Expired - Fee Related
- 2007-01-29 EP EP07717465.4A patent/EP1976491B1/en not_active Not-in-force
- 2007-01-29 JP JP2008552611A patent/JP5433236B2/ja not_active Expired - Fee Related
- 2007-01-29 BR BRPI0707324-0A patent/BRPI0707324A2/pt not_active IP Right Cessation
- 2007-01-29 NZ NZ570039A patent/NZ570039A/en not_active IP Right Cessation
- 2007-01-29 RU RU2008134912/15A patent/RU2490012C2/ru not_active IP Right Cessation
- 2007-01-29 WO PCT/US2007/061217 patent/WO2007090082A2/en not_active Ceased
- 2007-01-29 AU AU2007211091A patent/AU2007211091B8/en not_active Ceased
- 2007-01-29 ES ES11001973.4T patent/ES2550035T3/es active Active
- 2007-01-29 KR KR1020087021036A patent/KR101413613B1/ko not_active Expired - Fee Related
- 2007-01-29 CA CA2640460A patent/CA2640460C/en not_active Expired - Fee Related
- 2007-01-29 EP EP11001973.4A patent/EP2363117B1/en not_active Not-in-force
- 2007-01-29 CN CN201310113926.7A patent/CN103211779B/zh not_active Expired - Fee Related
- 2007-01-29 US US11/668,167 patent/US20070190145A1/en not_active Abandoned
- 2007-01-29 ES ES07717465T patent/ES2531215T3/es active Active
-
2008
- 2008-07-24 IL IL193020A patent/IL193020A0/en not_active IP Right Cessation
- 2008-07-25 ZA ZA2008/06497A patent/ZA200806497B/en unknown
-
2013
- 2013-08-08 JP JP2013165542A patent/JP5918179B2/ja not_active Expired - Fee Related
-
2015
- 2015-09-25 JP JP2015188001A patent/JP2016014048A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2640460A1 (en) | 2007-08-09 |
| EP1976491B1 (en) | 2014-12-17 |
| KR20080098627A (ko) | 2008-11-11 |
| CA2640460C (en) | 2015-05-26 |
| JP2013249305A (ja) | 2013-12-12 |
| RU2490012C2 (ru) | 2013-08-20 |
| NZ570039A (en) | 2011-07-29 |
| CN103211779B (zh) | 2016-03-16 |
| EP2363117B1 (en) | 2015-08-19 |
| JP5433236B2 (ja) | 2014-03-05 |
| JP2016014048A (ja) | 2016-01-28 |
| AU2007211091A8 (en) | 2013-08-29 |
| CN101410094A (zh) | 2009-04-15 |
| JP2009524697A (ja) | 2009-07-02 |
| WO2007090082A2 (en) | 2007-08-09 |
| JP5918179B2 (ja) | 2016-05-18 |
| ES2531215T3 (es) | 2015-03-11 |
| ES2550035T3 (es) | 2015-11-04 |
| AU2007211091A1 (en) | 2007-08-09 |
| AU2007211091B2 (en) | 2013-05-02 |
| RU2008134912A (ru) | 2010-03-10 |
| US20070190145A1 (en) | 2007-08-16 |
| EP2363117A1 (en) | 2011-09-07 |
| CN101410094B (zh) | 2013-04-17 |
| WO2007090082A3 (en) | 2007-12-21 |
| BRPI0707324A2 (pt) | 2011-05-03 |
| EP1976491A2 (en) | 2008-10-08 |
| AU2007211091B8 (en) | 2013-08-29 |
| CN103211779A (zh) | 2013-07-24 |
| KR101413613B1 (ko) | 2014-07-10 |
| IL193020A0 (en) | 2009-09-22 |
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