ZA200801742B - Bazedoxifene acetate formulations and manufacturing process thereof - Google Patents

Bazedoxifene acetate formulations and manufacturing process thereof

Info

Publication number
ZA200801742B
ZA200801742B ZA200801742A ZA200801742A ZA200801742B ZA 200801742 B ZA200801742 B ZA 200801742B ZA 200801742 A ZA200801742 A ZA 200801742A ZA 200801742 A ZA200801742 A ZA 200801742A ZA 200801742 B ZA200801742 B ZA 200801742B
Authority
ZA
South Africa
Prior art keywords
manufacturing process
bazedoxifene acetate
acetate formulations
formulations
bazedoxifene
Prior art date
Application number
ZA200801742A
Other languages
English (en)
Inventor
Syed M Shah
Eric C Ehrnsperger
Christopher R Diorio
Kadum A Ali
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37772333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200801742(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of ZA200801742B publication Critical patent/ZA200801742B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
ZA200801742A 2005-08-24 2008-02-22 Bazedoxifene acetate formulations and manufacturing process thereof ZA200801742B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71076105P 2005-08-24 2005-08-24

Publications (1)

Publication Number Publication Date
ZA200801742B true ZA200801742B (en) 2010-10-27

Family

ID=37772333

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200801742A ZA200801742B (en) 2005-08-24 2008-02-22 Bazedoxifene acetate formulations and manufacturing process thereof

Country Status (21)

Country Link
US (1) US7771744B2 (fr)
EP (1) EP1919456A2 (fr)
JP (2) JP2009506053A (fr)
KR (2) KR101584674B1 (fr)
CN (1) CN101304731B (fr)
AR (1) AR056471A1 (fr)
AU (1) AU2006283121A1 (fr)
BR (1) BRPI0615341A2 (fr)
CA (1) CA2620174A1 (fr)
CR (1) CR9746A (fr)
EC (1) ECSP088214A (fr)
GT (1) GT200600383A (fr)
IL (2) IL189648A (fr)
MX (1) MX2008002484A (fr)
NO (1) NO20080991L (fr)
PE (1) PE20070425A1 (fr)
RU (1) RU2417084C2 (fr)
SV (1) SV2008002825A (fr)
TW (1) TW200738281A (fr)
WO (1) WO2007024961A2 (fr)
ZA (1) ZA200801742B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20060167A1 (es) * 2004-04-08 2006-04-20 Wyeth Corp Formulaciones de dispersion solida que comprende acetato de bazedoxifeno
CN101304731B (zh) * 2005-08-24 2012-06-20 惠氏公司 醋酸苯卓昔芬制剂及其生产方法
EP2001450B1 (fr) * 2006-03-31 2019-01-30 Rubicon Research Private Limited Mixture directement compressible pour la manufacture des comprimés se désagrégeant dans la cavité orale
WO2008079342A2 (fr) * 2006-12-21 2008-07-03 Mallinckrodt Inc. Comprimés à désintégration par voie orale: composition utilisée et méthode de fabrication orale
US20100016582A1 (en) * 2008-02-11 2010-01-21 Wyeth Methods of converting polymorphic form b of bazedoxifene acetate to polymorphic form a of bazedoxifene acetate
ITMI20091109A1 (it) 2009-06-23 2010-12-24 Wyeth Corp Forma polimorfa d di bazedoxifene acetato e metodi per la sua preparazione
SG190406A1 (en) * 2010-11-30 2013-06-28 Wista Lab Ltd Formulations comprising methylthioninium chloride
EP2471770A1 (fr) * 2010-12-28 2012-07-04 Sandoz Ag Procédé pour la préparation de la forme pure polymorphe A d'acétate de bazédoxifène
WO2013182170A1 (fr) 2012-06-07 2013-12-12 Zentiva, K. S. Augmentation de la vitesse de dissolution d'une composition pharmaceutique comprenant de l'acétate de bazédoxifène
WO2013182169A1 (fr) 2012-06-07 2013-12-12 Zentiva, K. S. Procédé de préparation d'une formulation d'acétate de bazédoxifène sans anti-oxydant et stable du point de vue polymorphe et chimique
CN103877581B (zh) * 2014-03-24 2016-03-02 江苏知原药业有限公司 一种性能优异的乙酸巴多昔芬缓释制剂
WO2018182205A1 (fr) * 2017-03-30 2018-10-04 한미약품 주식회사 Composition pharmaceutique stabilisée contenant de l'acétate de bazedoxifène
KR101940569B1 (ko) * 2017-05-24 2019-01-21 아주대학교산학협력단 바제독시펜 또는 이의 약학적으로 허용가능한 염을 포함하는 약학 조성물
CN112076163B (zh) * 2019-06-14 2023-06-20 四川科伦药物研究院有限公司 一种醋酸巴多昔芬片的药物组合物及其制备方法
CN111004165A (zh) * 2019-12-03 2020-04-14 南京正济医药研究有限公司 一种醋酸巴多昔芬晶型a的制备方法
CN112754999A (zh) * 2021-01-23 2021-05-07 郑州泰丰制药有限公司 一种醋酸巴多昔芬组合物及醋酸巴多昔芬薄膜衣片制备方法
CN113368075A (zh) * 2021-06-29 2021-09-10 郑州泰丰制药有限公司 一种醋酸巴多昔芬片及其制备方法
AU2022334112A1 (en) * 2021-08-23 2024-03-07 Oxygen Biotech LLC Treatment of covid-19

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686094A (en) * 1991-04-01 1997-11-11 Theratech, Inc. Controlled release formulations for the treatment of xerostomia
PL184558B1 (pl) * 1995-06-22 2002-11-29 Akzo Nobel Nv Sposób wytwarzania tabletek kapsułek albo granulatu dezogestrelu
US5998402A (en) 1996-04-19 1999-12-07 American Home Products Corporation 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
US6479535B1 (en) 1998-05-15 2002-11-12 Wyeth 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
HUP0301117A3 (en) 2000-02-17 2004-01-28 Amgen Inc Thousand Oaks Imidazole derivatives kinase inhibitors, their use, process for their preparation and pharmaceutical compositions containing them
AR029538A1 (es) * 2000-07-06 2003-07-02 Wyeth Corp Composiciones farmaceuticas de agentes estrogenicos
SE0104140D0 (sv) 2001-12-07 2001-12-07 Astrazeneca Ab Novel Compounds
CA2489098A1 (fr) * 2002-06-13 2003-12-24 Wyeth Schemas therapeutiques du bazedoxifene
KR20060127875A (ko) 2004-01-13 2006-12-13 와이어쓰 아로마타제 억제제 요법-관련된 골다공증의 치료
CN1938272A (zh) * 2004-04-07 2007-03-28 惠氏公司 巴泽多昔芬醋酸盐的结晶多晶型物
RU2006132180A (ru) 2004-04-07 2008-05-20 Вайет (Us) Кристаллический полиморф базедоксифен ацетата
JP2007532548A (ja) 2004-04-07 2007-11-15 ワイス バゼドキシフェンアセテートの結晶質多形体
PE20060167A1 (es) * 2004-04-08 2006-04-20 Wyeth Corp Formulaciones de dispersion solida que comprende acetato de bazedoxifeno
CN101304731B (zh) * 2005-08-24 2012-06-20 惠氏公司 醋酸苯卓昔芬制剂及其生产方法

Also Published As

Publication number Publication date
KR20080043853A (ko) 2008-05-19
MX2008002484A (es) 2008-04-07
IL233392A0 (en) 2014-08-31
US7771744B2 (en) 2010-08-10
RU2417084C2 (ru) 2011-04-27
IL233392A (en) 2017-02-28
ECSP088214A (es) 2008-03-26
CN101304731B (zh) 2012-06-20
WO2007024961A3 (fr) 2007-06-28
EP1919456A2 (fr) 2008-05-14
RU2008107580A (ru) 2009-09-27
JP2013209419A (ja) 2013-10-10
SV2008002825A (es) 2008-06-30
CN101304731A (zh) 2008-11-12
IL189648A0 (en) 2008-08-07
KR20140088917A (ko) 2014-07-11
CR9746A (es) 2008-08-21
KR101584674B1 (ko) 2016-01-13
AR056471A1 (es) 2007-10-10
US20070048374A1 (en) 2007-03-01
IL189648A (en) 2014-07-31
GT200600383A (es) 2007-03-29
WO2007024961A2 (fr) 2007-03-01
CA2620174A1 (fr) 2007-03-01
PE20070425A1 (es) 2007-07-02
TW200738281A (en) 2007-10-16
AU2006283121A1 (en) 2007-03-01
NO20080991L (no) 2008-05-15
BRPI0615341A2 (pt) 2011-05-17
JP2009506053A (ja) 2009-02-12

Similar Documents

Publication Publication Date Title
ZA200801742B (en) Bazedoxifene acetate formulations and manufacturing process thereof
EP1889304A4 (fr) Compositions et procede thermoelectrique
TWI340137B (en) Preparation process
IL191759A0 (en) Ganaxolone formulations and methods for the making and use thereof
IL185199A0 (en) Indole compound and use thereof
IL185280A0 (en) Tetrahydroindolone and tetrahydroindazolone derivatives
EP1895838A4 (fr) Preparations et methodes
ZA200803987B (en) Novel process and formulations
EP1922309A4 (fr) Derives de n-phenyl-2-pyrimidine-amine et procede de preparation de ceux-ci
TWI350122B (en) Ceramic heater and manufacturing method thereof
HK1120660A1 (en) Electrode and manufacturing methods
IL184834A0 (en) Compositions and methods for the manufacture thereof
IL178235A0 (en) Bazedoxifene acetate solid dispersion formulations
PT2380575E (pt) Acetato de eslicarbazepina e utilização
IL187025A0 (en) Hard caramel containing isolmaltulose and process for the manufacture thereof
EP1921066A4 (fr) Composé de pyridylphénol et son utilisation
IL183702A0 (en) Difluoronucleosides and process for preparation thereof
GB0511807D0 (en) Process and compound
IL182970A0 (en) Compositions and processes for preparing 13-deoxy-anthracyclines
GB0501348D0 (en) Compositions and methods
IL194737A0 (en) 2-alkenyl-3-aminothiophene derivatives and processes for the preparation thereof
GB0523637D0 (en) Process and compounds
GB0403696D0 (en) Process and composition
GB0508495D0 (en) Electrode and manufacturing methods
GB0502481D0 (en) Cone cleaner