ZA200710337B - Aspartyl protease inhibitors - Google Patents

Aspartyl protease inhibitors

Info

Publication number
ZA200710337B
ZA200710337B ZA200710337A ZA200710337A ZA200710337B ZA 200710337 B ZA200710337 B ZA 200710337B ZA 200710337 A ZA200710337 A ZA 200710337A ZA 200710337 A ZA200710337 A ZA 200710337A ZA 200710337 B ZA200710337 B ZA 200710337B
Authority
ZA
South Africa
Prior art keywords
protease inhibitors
aspartyl protease
aspartyl
inhibitors
protease
Prior art date
Application number
ZA200710337A
Other languages
English (en)
Inventor
Zhu Zhaoning
Andrew W Stamford
Elizabeth M Smith
Mckittrick Brian
Huang Ying
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA200710337B publication Critical patent/ZA200710337B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200710337A 2005-06-14 2007-11-28 Aspartyl protease inhibitors ZA200710337B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69032605P 2005-06-14 2005-06-14

Publications (1)

Publication Number Publication Date
ZA200710337B true ZA200710337B (en) 2008-12-31

Family

ID=37074234

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200710337A ZA200710337B (en) 2005-06-14 2007-11-28 Aspartyl protease inhibitors

Country Status (18)

Country Link
US (1) US7759354B2 (xx)
EP (1) EP1896477B1 (xx)
JP (1) JP2008543840A (xx)
KR (1) KR20080031189A (xx)
CN (1) CN101198609A (xx)
AR (1) AR054620A1 (xx)
AT (1) ATE482214T1 (xx)
AU (1) AU2006259675A1 (xx)
CA (1) CA2610812A1 (xx)
DE (1) DE602006017073D1 (xx)
ES (1) ES2350854T3 (xx)
HK (1) HK1109151A1 (xx)
IL (1) IL187623A0 (xx)
MX (1) MX2007016175A (xx)
PE (1) PE20070018A1 (xx)
TW (1) TW200716644A (xx)
WO (1) WO2006138192A1 (xx)
ZA (1) ZA200710337B (xx)

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JP2015532282A (ja) 2012-09-28 2015-11-09 ヴァイティー ファーマシューティカルズ，インコーポレイテッド β−セクレターゼの阻害剤
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Also Published As

Publication number Publication date
ATE482214T1 (de) 2010-10-15
DE602006017073D1 (en) 2010-11-04
AU2006259675A1 (en) 2006-12-28
PE20070018A1 (es) 2007-03-08
CA2610812A1 (en) 2006-12-28
MX2007016175A (es) 2008-03-07
WO2006138192A1 (en) 2006-12-28
IL187623A0 (en) 2008-03-20
HK1109151A1 (en) 2008-05-30
US7759354B2 (en) 2010-07-20
JP2008543840A (ja) 2008-12-04
US20060281730A1 (en) 2006-12-14
KR20080031189A (ko) 2008-04-08
ES2350854T3 (es) 2011-01-27
EP1896477A1 (en) 2008-03-12
AR054620A1 (es) 2007-07-04
EP1896477B1 (en) 2010-09-22
TW200716644A (en) 2007-05-01
CN101198609A (zh) 2008-06-11

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