ZA200703826B - Manufacture process of N-substituted salicylamides - Google Patents

Manufacture process of N-substituted salicylamides

Info

Publication number
ZA200703826B
ZA200703826B ZA200703826A ZA200703826A ZA200703826B ZA 200703826 B ZA200703826 B ZA 200703826B ZA 200703826 A ZA200703826 A ZA 200703826A ZA 200703826 A ZA200703826 A ZA 200703826A ZA 200703826 B ZA200703826 B ZA 200703826B
Authority
ZA
South Africa
Prior art keywords
manufacture process
substituted salicylamides
salicylamides
substituted
manufacture
Prior art date
Application number
ZA200703826A
Other languages
English (en)
Inventor
Riss Bernard
Meier Ulrich
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34090175&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200703826(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200703826B publication Critical patent/ZA200703826B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200703826A 2004-12-16 2007-05-11 Manufacture process of N-substituted salicylamides ZA200703826B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0427603.6A GB0427603D0 (en) 2004-12-16 2004-12-16 Organic compounds

Publications (1)

Publication Number Publication Date
ZA200703826B true ZA200703826B (en) 2008-08-27

Family

ID=34090175

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200703826A ZA200703826B (en) 2004-12-16 2007-05-11 Manufacture process of N-substituted salicylamides

Country Status (24)

Country Link
US (1) US8461385B2 (enExample)
EP (2) EP2955171A1 (enExample)
JP (1) JP5224816B2 (enExample)
KR (1) KR101287233B1 (enExample)
CN (1) CN101080384B (enExample)
AR (1) AR055007A1 (enExample)
AU (1) AU2005315850B2 (enExample)
BR (1) BRPI0519327A2 (enExample)
CA (1) CA2587213C (enExample)
ES (1) ES2547349T3 (enExample)
GB (1) GB0427603D0 (enExample)
GT (1) GT200500353A (enExample)
IL (1) IL183366A0 (enExample)
MA (1) MA29092B1 (enExample)
MX (1) MX2007007211A (enExample)
NO (1) NO338969B1 (enExample)
PE (1) PE20060740A1 (enExample)
PL (1) PL1838664T3 (enExample)
PT (1) PT1838664E (enExample)
RU (1) RU2404158C2 (enExample)
TN (1) TNSN07229A1 (enExample)
TW (1) TW200635880A (enExample)
WO (1) WO2006063821A1 (enExample)
ZA (1) ZA200703826B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20070548A1 (es) * 2005-09-19 2007-07-12 Emisphere Tech Inc Formas cristalinas de la sal de di-sodio del acido n-(5-clorosaliciloil)-8-aminocaprilico
US8022048B2 (en) 2007-11-02 2011-09-20 Emisphere Technologies, Inc. Method of treating vitamin B12 deficiency
CN109473182B (zh) * 2018-11-12 2021-10-19 北京北排科技有限公司 一种基于深度信念网络的mbr膜透水率智能检测方法
AU2020277650B2 (en) * 2019-05-20 2025-03-13 Lonza Guangzhou Pharmaceutical Ltd. Method for preparation of carsalam
CN115260116B (zh) * 2022-08-19 2024-04-12 株洲壹诺生物技术有限公司 8-(2-羟基苯甲酰胺基)辛酸钠及苯并噁嗪-2,4-二酮和8-溴辛酸乙酯的制法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU382610A1 (ru) * 1968-07-08 1973-05-25 Способ получения амидов карбоновых кислот
NZ534409A (en) 1999-04-05 2006-03-31 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
KR20020013936A (ko) * 1999-06-25 2002-02-21 추후제출 치환된 페녹시아세트산
JP4799794B2 (ja) * 2000-03-21 2011-10-26 エミスフェアー・テクノロジーズ・インク ジカルボキシル化中間体を介してアルキル化サリチルアミドを調製する方法。
AU2001275231A1 (en) 2000-06-02 2001-12-11 Emisphere Technologies, Inc. Method of preparing salicylamides
WO2003057650A2 (en) * 2002-01-09 2003-07-17 Emisphere Technologies, Inc. Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate
NZ523017A (en) * 2000-06-29 2004-10-29 Emisphere Tech Inc Compounds and compositions for delivering active agents and preparation method thereof
AU2001296865A1 (en) * 2000-09-06 2002-03-22 Emisphere Technologies, Inc. (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
AU2003208945B2 (en) * 2002-02-20 2008-05-01 Emisphere Technologies, Inc Method for administering GLP-1 molecules
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin

Also Published As

Publication number Publication date
TNSN07229A1 (en) 2008-11-21
NO338969B1 (no) 2016-11-07
GB0427603D0 (en) 2005-01-19
AR055007A1 (es) 2007-08-01
CN101080384B (zh) 2011-06-15
CN101080384A (zh) 2007-11-28
PL1838664T3 (pl) 2016-04-29
JP2008524142A (ja) 2008-07-10
NO20073548L (no) 2007-09-17
EP1838664B1 (en) 2015-07-15
WO2006063821A1 (en) 2006-06-22
KR101287233B1 (ko) 2013-07-17
CA2587213A1 (en) 2006-06-22
US20090253811A1 (en) 2009-10-08
PT1838664E (pt) 2015-10-16
MX2007007211A (es) 2007-08-15
KR20070086276A (ko) 2007-08-27
EP1838664A1 (en) 2007-10-03
US8461385B2 (en) 2013-06-11
TW200635880A (en) 2006-10-16
GT200500353A (es) 2006-07-17
AU2005315850B2 (en) 2009-11-05
ES2547349T3 (es) 2015-10-05
AU2005315850A1 (en) 2006-06-22
PE20060740A1 (es) 2006-09-04
IL183366A0 (en) 2007-09-20
BRPI0519327A2 (pt) 2009-01-13
CA2587213C (en) 2015-05-19
MA29092B1 (fr) 2007-12-03
RU2404158C2 (ru) 2010-11-20
EP2955171A1 (en) 2015-12-16
RU2007126972A (ru) 2009-01-27
JP5224816B2 (ja) 2013-07-03

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