ZA200703452B - Particles for treatment of pulmonary infection - Google Patents
Particles for treatment of pulmonary infection Download PDFInfo
- Publication number
- ZA200703452B ZA200703452B ZA200703452A ZA200703452A ZA200703452B ZA 200703452 B ZA200703452 B ZA 200703452B ZA 200703452 A ZA200703452 A ZA 200703452A ZA 200703452 A ZA200703452 A ZA 200703452A ZA 200703452 B ZA200703452 B ZA 200703452B
- Authority
- ZA
- South Africa
- Prior art keywords
- formulation
- aggregates
- particles
- capreomycin
- treatment
- Prior art date
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Epidemiology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
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- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
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| US62373804P | 2004-10-29 | 2004-10-29 |
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| ZA200703452A ZA200703452B (en) | 2004-10-29 | 2007-04-26 | Particles for treatment of pulmonary infection |
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| US (1) | US8846607B2 (pt) |
| EP (1) | EP1809252A2 (pt) |
| JP (1) | JP2008518007A (pt) |
| CN (1) | CN101090711A (pt) |
| AU (1) | AU2005334514B2 (pt) |
| BR (1) | BRPI0517374A (pt) |
| CA (1) | CA2585859C (pt) |
| IL (1) | IL182785A0 (pt) |
| RU (1) | RU2007119721A (pt) |
| WO (1) | WO2007011396A2 (pt) |
| ZA (1) | ZA200703452B (pt) |
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| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| EP2421518A2 (en) * | 2009-04-24 | 2012-02-29 | Schering Corporation | Agglomerate formulations including active pharmaceutical agents with targeted particle sizes |
| CN102458373A (zh) | 2009-05-27 | 2012-05-16 | 株式会社三养生物制药 | 生物利用度提高的包含难溶性药物的微球及其制备方法 |
| CN102573886A (zh) * | 2009-09-17 | 2012-07-11 | 相互制药公司 | 用抗病毒剂治疗哮喘的方法 |
| CN102225058A (zh) * | 2011-06-22 | 2011-10-26 | 中国药科大学 | 磷酸奥司他韦吸入粉雾剂及其制备方法 |
| KR20140147891A (ko) | 2012-04-13 | 2014-12-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 응집체 입자 |
| RU2562550C2 (ru) * | 2013-12-19 | 2015-09-10 | Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт бруцеллеза и туберкулеза животных" (ФГБНУ ВНИИБТЖ) | Способ специфической профилактики туберкулеза |
| AU2016315478B2 (en) * | 2015-09-03 | 2023-07-13 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
| US20200246268A1 (en) * | 2017-06-08 | 2020-08-06 | Pai Life Sciences Inc. | Cpzen compositions and uses |
| CN109260180A (zh) * | 2017-07-17 | 2019-01-25 | 北京盈科瑞创新药物研究有限公司 | 一种盐酸莫西沙星雾化吸入用溶液制剂及其制备方法 |
| JP7417532B2 (ja) | 2018-03-19 | 2024-01-18 | ノババックス，インコーポレイテッド | 多価インフルエンザナノ粒子ワクチン |
| EA202190331A1 (ru) * | 2018-07-24 | 2021-06-17 | Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем | Композиции терапевтически активных частиц с модифицированной поверхностью, полученные путем ультрабыстрой заморозки |
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| JPWO2022044582A1 (pt) * | 2020-08-28 | 2022-03-03 | ||
| KR20230141782A (ko) * | 2021-02-01 | 2023-10-10 | 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. | 프레토마니드 무정형 |
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| US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| IT1228459B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore con svuotamento regolare e completo della capsula. |
| IS1796B (is) | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
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| US6143211A (en) | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| US20020052310A1 (en) | 1997-09-15 | 2002-05-02 | Massachusetts Institute Of Technology The Penn State Research Foundation | Particles for inhalation having sustained release properties |
| US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5985309A (en) | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US6517860B1 (en) * | 1996-12-31 | 2003-02-11 | Quadrant Holdings Cambridge, Ltd. | Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery |
| US20030059471A1 (en) * | 1997-12-15 | 2003-03-27 | Compton Bruce Jon | Oral delivery formulation |
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| HU229310B1 (en) | 1999-10-29 | 2013-10-28 | Nektar Therapeutics | Dry powder compositions having improved dispersivity |
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| GB0216562D0 (en) * | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
| AU2003270659A1 (en) * | 2002-09-12 | 2004-04-30 | The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services | Aerosolized capreomycin for inhibition of pulmonary tuberculosis |
| CA2500065A1 (en) * | 2002-09-30 | 2004-04-15 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
| DE502004011696D1 (de) * | 2003-02-10 | 2010-11-11 | Bayer Schering Pharma Ag | Behandlung bakterieller erkrankungen der atmungsorgane durch lokale applikation von fluorchinolonen |
-
2005
- 2005-10-19 EP EP05858453A patent/EP1809252A2/en not_active Withdrawn
- 2005-10-19 AU AU2005334514A patent/AU2005334514B2/en not_active Ceased
- 2005-10-19 US US11/720,595 patent/US8846607B2/en not_active Expired - Fee Related
- 2005-10-19 RU RU2007119721/15A patent/RU2007119721A/ru not_active Application Discontinuation
- 2005-10-19 CA CA2585859A patent/CA2585859C/en not_active Expired - Fee Related
- 2005-10-19 CN CNA2005800449753A patent/CN101090711A/zh active Pending
- 2005-10-19 WO PCT/US2005/037484 patent/WO2007011396A2/en active Application Filing
- 2005-10-19 BR BRPI0517374-4A patent/BRPI0517374A/pt not_active IP Right Cessation
- 2005-10-19 JP JP2007538989A patent/JP2008518007A/ja active Pending
-
2007
- 2007-04-25 IL IL182785A patent/IL182785A0/en unknown
- 2007-04-26 ZA ZA200703452A patent/ZA200703452B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007011396A3 (en) | 2007-05-03 |
| EP1809252A2 (en) | 2007-07-25 |
| CA2585859C (en) | 2012-03-06 |
| AU2005334514B2 (en) | 2009-11-26 |
| US20080213373A1 (en) | 2008-09-04 |
| JP2008518007A (ja) | 2008-05-29 |
| CN101090711A (zh) | 2007-12-19 |
| CA2585859A1 (en) | 2007-01-25 |
| BRPI0517374A (pt) | 2008-10-07 |
| IL182785A0 (en) | 2007-09-20 |
| AU2005334514A1 (en) | 2007-01-25 |
| WO2007011396A2 (en) | 2007-01-25 |
| RU2007119721A (ru) | 2008-12-10 |
| US8846607B2 (en) | 2014-09-30 |
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