ZA200703369B - Collagen producing plants and methods of generating and using same - Google Patents

Collagen producing plants and methods of generating and using same

Info

Publication number
ZA200703369B
ZA200703369B ZA200703369A ZA200703369A ZA200703369B ZA 200703369 B ZA200703369 B ZA 200703369B ZA 200703369 A ZA200703369 A ZA 200703369A ZA 200703369 A ZA200703369 A ZA 200703369A ZA 200703369 B ZA200703369 B ZA 200703369B
Authority
ZA
South Africa
Prior art keywords
collagen
generating
methods
same
producing plants
Prior art date
Application number
ZA200703369A
Other languages
English (en)
Inventor
Shoseyov Oded
Stein Hanan
Original Assignee
Collplant Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35788568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200703369(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Collplant Ltd filed Critical Collplant Ltd
Publication of ZA200703369B publication Critical patent/ZA200703369B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fertilizers (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
ZA200703369A 2004-09-29 2007-04-25 Collagen producing plants and methods of generating and using same ZA200703369B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61371904P 2004-09-29 2004-09-29

Publications (1)

Publication Number Publication Date
ZA200703369B true ZA200703369B (en) 2008-08-27

Family

ID=35788568

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200703369A ZA200703369B (en) 2004-09-29 2007-04-25 Collagen producing plants and methods of generating and using same

Country Status (14)

Country Link
EP (6) EP2816117B1 (enExample)
JP (2) JP5100386B2 (enExample)
KR (1) KR20070083870A (enExample)
CN (1) CN101065491B (enExample)
AT (1) ATE479762T1 (enExample)
BR (1) BRPI0516303B1 (enExample)
CA (1) CA2582051C (enExample)
DE (1) DE602005023332D1 (enExample)
HK (1) HK1251611B (enExample)
IL (1) IL182320A (enExample)
MX (1) MX2007003767A (enExample)
NZ (1) NZ554787A (enExample)
WO (1) WO2006035442A2 (enExample)
ZA (1) ZA200703369B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378506B2 (en) 1997-07-21 2008-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6639050B1 (en) 1997-07-21 2003-10-28 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
WO2005069845A2 (en) 2004-01-14 2005-08-04 Ohio University Methods of producing peptides/proteins in plants and peptides/proteins produced thereby
CA2573918A1 (en) 2004-04-19 2005-11-24 Ohio University Cross-linkable glycoproteins and methods of making the same
DE602005023332D1 (de) 2004-09-29 2010-10-14 Collplant Ltd Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
EP2084285A4 (en) * 2006-07-10 2010-01-13 Univ Ohio COEXPRESSION OF PROLIN HYDROXYLASES TO FACILITATE HYP-GLYCOSYLATION OF PROTEINS EXPRESSED AND SEPARATED IN PLANT CELLS
WO2009053985A1 (en) * 2007-10-26 2009-04-30 Collplant Ltd. Methods of processing recombinant procollagen
EP2220112B1 (en) 2007-11-26 2015-08-26 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions comprising fibrous polypeptides and polysaccharides
US9095569B2 (en) * 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
EP2504472A1 (en) 2009-11-24 2012-10-03 Collplant Ltd. Method of generating collagen fibers
WO2012066543A2 (en) 2010-11-16 2012-05-24 Collplant Ltd. Collagen structures and method of fabricating the same
US9687583B2 (en) 2011-09-01 2017-06-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Adhesive biopolymers and uses thereof
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
KR102063686B1 (ko) * 2012-01-02 2020-02-11 (주)아모레퍼시픽 콩뿌리 추출물을 함유하는 피부 외용제 조성물
ES2883580T3 (es) 2013-03-21 2021-12-09 Collplant Ltd Composiciones que comprenden colágeno y PRP para la regeneración de tejidos y su método de producción
AU2014234962C1 (en) * 2013-03-21 2019-01-17 Evonik Operations Gmbh Purification of triple helical proteins
GB201308120D0 (en) * 2013-05-06 2013-06-12 Baden Wuerttemberg Stiftung Gmbh Recombinant protein and method for its production
WO2015031950A1 (en) 2013-09-09 2015-03-12 Commonwealth Scientific And Industrial Research Organisation Modified bacterial collagen-like proteins
BR112017010555A2 (pt) 2014-11-20 2018-02-27 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd composições e métodos para produção de polipeptídeos com padrão de glicosilação modificado em células vegetais
US12115276B2 (en) 2017-06-09 2024-10-15 Collplant Ltd. Additive manufacturing using recombinant collagen-containing formulation
WO2019056377A1 (zh) * 2017-09-25 2019-03-28 吴侑峻 非人类转基因哺乳动物及从其结缔组织分离的蛋白质粗萃物及其方法与用途
CA3099139A1 (en) 2018-05-03 2019-11-07 Collplant Ltd. Dermal fillers and applications thereof
WO2020026241A1 (en) 2018-07-31 2020-02-06 Collplant Ltd. Tobacco transgenic event and methods for detection and use thereof
CN109988234A (zh) * 2019-02-20 2019-07-09 江苏悦智生物医药有限公司 酵母重组人源I型胶原α1链蛋白、合成方法及其应用
KR20220152190A (ko) * 2019-11-11 2022-11-15 알렉산더 이브게니비치 캄차로브 콜라겐과 추가 첨가제를 함유한 음료
FR3105792B1 (fr) 2019-12-26 2022-08-12 Michel Assor Matériau biocomposite collagène/matrice polymérique poreuse et son utilisation comme implant de réparation de lésions méniscales du genou et/ou de prévention ou de traitement de l’arthrose du genou
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
KR20240169060A (ko) 2022-04-04 2024-12-02 스위프트파마 비브이 식물에서 생산된 재조합 거미줄 강화 콜라겐 단백질 및 이의 용도
WO2024029529A1 (ja) * 2022-08-02 2024-02-08 株式会社 UniBio コラーゲン産生方法
CN117209592A (zh) * 2023-07-26 2023-12-12 浙江大学 一种人源化i型胶原蛋白及其制备方法与应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
JPS6054684A (ja) 1983-09-05 1985-03-29 Teijin Ltd 新規ｄνａ及びハイブリツドｄνａ
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
CA1288073C (en) 1985-03-07 1991-08-27 Paul G. Ahlquist Rna transformation vector
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
GB8608850D0 (en) 1986-04-11 1986-05-14 Diatech Ltd Packaging system
JPS6314693A (ja) 1986-07-04 1988-01-21 Sumitomo Chem Co Ltd 植物ウイルスｒｎａベクタ−
EP0278667B1 (en) 1987-02-09 1994-07-20 Mycogen Plant Science, Inc. Hybrid RNA virus
US5316931A (en) 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5693507A (en) 1988-09-26 1997-12-02 Auburn University Genetic engineering of plant chloroplasts
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5593859A (en) * 1991-10-23 1997-01-14 Thomas Jefferson University Synthesis of human procollagens and collagens in recombinant DNA systems
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
FR2757874B1 (fr) * 1996-12-17 2003-04-25 Biocem Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations
US6642437B1 (en) 1997-09-30 2003-11-04 The Regents Of The University Of California Production of proteins in plant seeds
AU1573601A (en) * 1999-10-21 2001-04-30 Monsanto Company Post-translational modification of recombinant proteins produced in plants
CA2399371A1 (en) * 1999-11-12 2001-05-17 Fibrogen, Inc. Animal collagens and gelatins
ATE374787T1 (de) * 1999-11-12 2007-10-15 Fibrogen Inc Rinder-kollagen und verfahren zur herstelling rekombinantes gelatin
CA2451765A1 (en) * 2001-06-05 2002-12-12 Karen K. Oishi Gene expression and production of tgf-b proteins including bioactive mullerian inhibiting substance from plants
JP4426307B2 (ja) * 2002-02-08 2010-03-03 ノボザイムス アクティーゼルスカブ フィターゼ変異体
MXPA05005777A (es) * 2002-12-19 2006-03-08 Univ Bristol Metodo novedoso para produccion de acidos grasos poliinsaturados.
JP2006512069A (ja) * 2002-12-20 2006-04-13 ビーエーエスエフ　アクチェンゲゼルシャフト 除草剤の標的としてのリンゴ酸デヒドロゲナーゼ
DE602005023332D1 (de) 2004-09-29 2010-10-14 Collplant Ltd Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung

Also Published As

Publication number Publication date
EP1809751B1 (en) 2010-09-01
WO2006035442A8 (en) 2006-06-29
MX2007003767A (es) 2007-07-17
JP5100386B2 (ja) 2012-12-19
DE602005023332D1 (de) 2010-10-14
EP3312282A1 (en) 2018-04-25
BRPI0516303A (pt) 2008-09-02
EP2816117B1 (en) 2016-11-30
JP5517309B2 (ja) 2014-06-11
CN101065491A (zh) 2007-10-31
EP2816117A3 (en) 2015-05-27
NZ554787A (en) 2009-05-31
IL182320A (en) 2015-06-30
WO2006035442A3 (en) 2006-05-04
EP1809751A2 (en) 2007-07-25
EP3312282B1 (en) 2019-07-03
HK1251611B (en) 2020-06-19
EP2357241A1 (en) 2011-08-17
CA2582051C (en) 2015-08-11
JP2008514225A (ja) 2008-05-08
HK1160176A1 (en) 2012-08-10
EP3088528B1 (en) 2019-07-03
EP2816117A2 (en) 2014-12-24
ATE479762T1 (de) 2010-09-15
EP2357241B1 (en) 2015-03-04
IL182320A0 (en) 2007-07-24
WO2006035442A2 (en) 2006-04-06
JP2012085644A (ja) 2012-05-10
CA2582051A1 (en) 2006-04-06
CN101065491B (zh) 2012-01-11
EP3088528A1 (en) 2016-11-02
HK1114405A1 (en) 2008-10-31
KR20070083870A (ko) 2007-08-24
EP2360261A1 (en) 2011-08-24
BRPI0516303B1 (pt) 2021-04-13

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