DE602005023332D1 - Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung - Google Patents
Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendungInfo
- Publication number
- DE602005023332D1 DE602005023332D1 DE602005023332T DE602005023332T DE602005023332D1 DE 602005023332 D1 DE602005023332 D1 DE 602005023332D1 DE 602005023332 T DE602005023332 T DE 602005023332T DE 602005023332 T DE602005023332 T DE 602005023332T DE 602005023332 D1 DE602005023332 D1 DE 602005023332D1
- Authority
- DE
- Germany
- Prior art keywords
- plant
- collagen
- collagenproduzierende
- plants
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract 2
- 102200024044 rs1555523872 Human genes 0.000 abstract 3
- 108010035532 Collagen Proteins 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 2
- 101710096389 Collagen alpha chain Proteins 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fertilizers (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61371904P | 2004-09-29 | 2004-09-29 | |
| PCT/IL2005/001045 WO2006035442A2 (en) | 2004-09-29 | 2005-09-28 | Collagen producing plants and methods of generating and using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005023332D1 true DE602005023332D1 (de) | 2010-10-14 |
Family
ID=35788568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005023332T Active DE602005023332D1 (de) | 2004-09-29 | 2005-09-28 | Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung |
Country Status (14)
| Country | Link |
|---|---|
| EP (6) | EP3312282B1 (enExample) |
| JP (2) | JP5100386B2 (enExample) |
| KR (1) | KR20070083870A (enExample) |
| CN (1) | CN101065491B (enExample) |
| AT (1) | ATE479762T1 (enExample) |
| BR (1) | BRPI0516303B1 (enExample) |
| CA (1) | CA2582051C (enExample) |
| DE (1) | DE602005023332D1 (enExample) |
| HK (1) | HK1251611B (enExample) |
| IL (1) | IL182320A (enExample) |
| MX (1) | MX2007003767A (enExample) |
| NZ (1) | NZ554787A (enExample) |
| WO (1) | WO2006035442A2 (enExample) |
| ZA (1) | ZA200703369B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7378506B2 (en) | 1997-07-21 | 2008-05-27 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| US6639050B1 (en) | 1997-07-21 | 2003-10-28 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| EP1711533B1 (en) | 2004-01-14 | 2013-12-11 | Ohio University | Methods of producing peptides/proteins in plants and peptides/proteins produced thereby |
| CA2573918A1 (en) | 2004-04-19 | 2005-11-24 | Ohio University | Cross-linkable glycoproteins and methods of making the same |
| MX2007003767A (es) | 2004-09-29 | 2007-07-17 | Collplant Ltd | Colageno recombinante producido en planta. |
| US8455717B2 (en) | 2004-09-29 | 2013-06-04 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| WO2008008766A2 (en) * | 2006-07-10 | 2008-01-17 | Ohio University | Co-expression of proline hydroxylases to facilitate hyp-glycosylation of proteins expressed and secreted in plant cells |
| EP2220246B1 (en) | 2007-10-26 | 2015-05-20 | Collplant Ltd. | Methods of processing recombinant procollagen |
| EP2220112B1 (en) | 2007-11-26 | 2015-08-26 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Compositions comprising fibrous polypeptides and polysaccharides |
| PL2288376T3 (pl) * | 2008-04-18 | 2016-07-29 | Collplant Ltd | Sposoby generowania i wykorzystywania prokolagenu |
| EP2504472A1 (en) | 2009-11-24 | 2012-10-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2640877A2 (en) | 2010-11-16 | 2013-09-25 | Collplant Ltd. | Collagen structures and method of fabricating the same |
| US9687583B2 (en) | 2011-09-01 | 2017-06-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Adhesive biopolymers and uses thereof |
| WO2013093921A1 (en) | 2011-12-20 | 2013-06-27 | Collplant Ltd. | Collagen coated synthetic polymer fibers |
| KR102063686B1 (ko) * | 2012-01-02 | 2020-02-11 | (주)아모레퍼시픽 | 콩뿌리 추출물을 함유하는 피부 외용제 조성물 |
| TWI657094B (zh) * | 2013-03-21 | 2019-04-21 | 全民科學與工業研究機構 | 三螺旋蛋白質之純化 |
| CA2907680A1 (en) | 2013-03-21 | 2014-09-25 | Collplant Ltd. | Compositions comprising collagen and prp for tissue regeneration |
| GB201308120D0 (en) * | 2013-05-06 | 2013-06-12 | Baden Wuerttemberg Stiftung Gmbh | Recombinant protein and method for its production |
| CN105764920B (zh) | 2013-09-09 | 2020-07-24 | 联邦科学工业研究组织 | 修饰的细菌胶原蛋白样蛋白 |
| CN107810271B (zh) | 2014-11-20 | 2021-09-28 | 耶路撒冷希伯来大学伊萨姆研发公司 | 用于在植物细胞中生产具有改变的糖基化模式的多肽的组合物和方法 |
| WO2018225076A1 (en) | 2017-06-09 | 2018-12-13 | Collplant Ltd. | Additive manufacturing using recombinant collagen-containing formulation |
| WO2019056377A1 (zh) * | 2017-09-25 | 2019-03-28 | 吴侑峻 | 非人类转基因哺乳动物及从其结缔组织分离的蛋白质粗萃物及其方法与用途 |
| IL278370B2 (en) | 2018-05-03 | 2024-02-01 | Collplant Ltd | Dermal fillers and their uses |
| JP7479343B2 (ja) * | 2018-07-31 | 2024-05-08 | コルプラント リミテッド | タバコのトランスジェニックイベント、並びにその検出方法およびその使用 |
| CN109988234A (zh) * | 2019-02-20 | 2019-07-09 | 江苏悦智生物医药有限公司 | 酵母重组人源I型胶原α1链蛋白、合成方法及其应用 |
| JP2023501625A (ja) * | 2019-11-11 | 2023-01-18 | エフゲニエヴィチ カムチャロフ、アレクサンドル | コラーゲンおよび追加の添加剤入り飲料 |
| FR3105792B1 (fr) | 2019-12-26 | 2022-08-12 | Michel Assor | Matériau biocomposite collagène/matrice polymérique poreuse et son utilisation comme implant de réparation de lésions méniscales du genou et/ou de prévention ou de traitement de l’arthrose du genou |
| WO2021229577A1 (en) | 2020-05-12 | 2021-11-18 | Collplant Ltd. | Collagen as a delivery tool for metal-based anti-viral agents |
| EP4504761A1 (en) | 2022-04-04 | 2025-02-12 | SwiftPharma BV | Recombinant spider silk-reinforced collagen proteins produced in plants and the use thereof |
| EP4567113A1 (en) * | 2022-08-02 | 2025-06-11 | Unibio Corporation | Collagen production method |
| CN117209592A (zh) * | 2023-07-26 | 2023-12-12 | 浙江大学 | 一种人源化i型胶原蛋白及其制备方法与应用 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| CA1192510A (en) | 1981-05-27 | 1985-08-27 | Lawrence E. Pelcher | Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom |
| JPS6054684A (ja) | 1983-09-05 | 1985-03-29 | Teijin Ltd | 新規dνa及びハイブリツドdνa |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| CA1288073C (en) | 1985-03-07 | 1991-08-27 | Paul G. Ahlquist | Rna transformation vector |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| GB8608850D0 (en) | 1986-04-11 | 1986-05-14 | Diatech Ltd | Packaging system |
| JPS6314693A (ja) | 1986-07-04 | 1988-01-21 | Sumitomo Chem Co Ltd | 植物ウイルスrnaベクタ− |
| EP0278667B1 (en) | 1987-02-09 | 1994-07-20 | Mycogen Plant Science, Inc. | Hybrid RNA virus |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5693507A (en) | 1988-09-26 | 1997-12-02 | Auburn University | Genetic engineering of plant chloroplasts |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5593859A (en) * | 1991-10-23 | 1997-01-14 | Thomas Jefferson University | Synthesis of human procollagens and collagens in recombinant DNA systems |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| FR2757874B1 (fr) | 1996-12-17 | 2003-04-25 | Biocem | Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| WO1999016890A2 (en) | 1997-09-30 | 1999-04-08 | The Regents Of The University Of California | Production of proteins in plant seeds |
| WO2003066847A2 (en) * | 2002-02-08 | 2003-08-14 | Novozymes A/S | Phytase variants |
| CA2388432A1 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| WO2001034647A2 (en) * | 1999-11-12 | 2001-05-17 | Fibrogen, Inc. | Animal collagens and gelatins |
| CA2399371A1 (en) | 1999-11-12 | 2001-05-17 | Fibrogen, Inc. | Animal collagens and gelatins |
| EP1399572A4 (en) * | 2001-06-05 | 2005-02-09 | Karen K Oishi | GENE EXPRESSION AND PRODUCTION OF TGF-B PROTEINS COMPRISING A BIOACTIVE MULLERIAN INHIBITORY SUBSTANCE FROM PLANTS |
| MXPA05005777A (es) * | 2002-12-19 | 2006-03-08 | Univ Bristol | Metodo novedoso para produccion de acidos grasos poliinsaturados. |
| EP1587920A1 (de) * | 2002-12-20 | 2005-10-26 | Basf Aktiengesellschaft | Malat dehydrogenase als target für herbizide |
| MX2007003767A (es) | 2004-09-29 | 2007-07-17 | Collplant Ltd | Colageno recombinante producido en planta. |
-
2005
- 2005-09-28 MX MX2007003767A patent/MX2007003767A/es active IP Right Grant
- 2005-09-28 EP EP17205280.5A patent/EP3312282B1/en not_active Expired - Lifetime
- 2005-09-28 EP EP14185576.7A patent/EP2816117B1/en not_active Revoked
- 2005-09-28 DE DE602005023332T patent/DE602005023332D1/de active Active
- 2005-09-28 EP EP10181115A patent/EP2360261A1/en not_active Ceased
- 2005-09-28 EP EP16171177.5A patent/EP3088528B1/en active Active
- 2005-09-28 CA CA2582051A patent/CA2582051C/en active Active
- 2005-09-28 BR BRPI0516303-0A patent/BRPI0516303B1/pt active IP Right Grant
- 2005-09-28 AT AT05789469T patent/ATE479762T1/de not_active IP Right Cessation
- 2005-09-28 JP JP2007534176A patent/JP5100386B2/ja not_active Expired - Lifetime
- 2005-09-28 KR KR1020077009817A patent/KR20070083870A/ko not_active Withdrawn
- 2005-09-28 EP EP05789469A patent/EP1809751B1/en not_active Revoked
- 2005-09-28 NZ NZ554787A patent/NZ554787A/en not_active IP Right Cessation
- 2005-09-28 EP EP10168971.9A patent/EP2357241B1/en not_active Revoked
- 2005-09-28 CN CN2005800408217A patent/CN101065491B/zh not_active Expired - Lifetime
- 2005-09-28 WO PCT/IL2005/001045 patent/WO2006035442A2/en not_active Ceased
-
2007
- 2007-03-29 IL IL182320A patent/IL182320A/en active IP Right Grant
- 2007-04-25 ZA ZA200703369A patent/ZA200703369B/xx unknown
-
2011
- 2011-11-29 JP JP2011259678A patent/JP5517309B2/ja not_active Expired - Fee Related
-
2018
- 2018-08-23 HK HK18110838.5A patent/HK1251611B/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: COLLPLANT LTD., NES ZIONA, IL |