CA2582051C - Collagen producing plants and methods of generating and using same - Google Patents
Collagen producing plants and methods of generating and using same Download PDFInfo
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- CA2582051C CA2582051C CA2582051A CA2582051A CA2582051C CA 2582051 C CA2582051 C CA 2582051C CA 2582051 A CA2582051 A CA 2582051A CA 2582051 A CA2582051 A CA 2582051A CA 2582051 C CA2582051 C CA 2582051C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8273—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for drought, cold, salt resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
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- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fertilizers (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61371904P | 2004-09-29 | 2004-09-29 | |
| US60/613,719 | 2004-09-29 | ||
| PCT/IL2005/001045 WO2006035442A2 (en) | 2004-09-29 | 2005-09-28 | Collagen producing plants and methods of generating and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2582051A1 CA2582051A1 (en) | 2006-04-06 |
| CA2582051C true CA2582051C (en) | 2015-08-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2582051A Active CA2582051C (en) | 2004-09-29 | 2005-09-28 | Collagen producing plants and methods of generating and using same |
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| JP (2) | JP5100386B2 (enExample) |
| KR (1) | KR20070083870A (enExample) |
| CN (1) | CN101065491B (enExample) |
| AT (1) | ATE479762T1 (enExample) |
| BR (1) | BRPI0516303B1 (enExample) |
| CA (1) | CA2582051C (enExample) |
| DE (1) | DE602005023332D1 (enExample) |
| HK (1) | HK1251611B (enExample) |
| IL (1) | IL182320A (enExample) |
| MX (1) | MX2007003767A (enExample) |
| NZ (1) | NZ554787A (enExample) |
| WO (1) | WO2006035442A2 (enExample) |
| ZA (1) | ZA200703369B (enExample) |
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| US7378506B2 (en) | 1997-07-21 | 2008-05-27 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| US6639050B1 (en) | 1997-07-21 | 2003-10-28 | Ohio University | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins |
| WO2005069845A2 (en) | 2004-01-14 | 2005-08-04 | Ohio University | Methods of producing peptides/proteins in plants and peptides/proteins produced thereby |
| US8623812B2 (en) | 2004-04-19 | 2014-01-07 | Ohio University | Cross-linkable glycoproteins and methods of making the same |
| US8455717B2 (en) | 2004-09-29 | 2013-06-04 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| JP5100386B2 (ja) | 2004-09-29 | 2012-12-19 | コルプラント リミテッド | コラーゲン生産植物及びその作成方法及びその使用 |
| EP2084285A4 (en) * | 2006-07-10 | 2010-01-13 | Univ Ohio | COEXPRESSION OF PROLIN HYDROXYLASES TO FACILITATE HYP-GLYCOSYLATION OF PROTEINS EXPRESSED AND SEPARATED IN PLANT CELLS |
| US8759487B2 (en) | 2007-10-26 | 2014-06-24 | Collplant Ltd. | Methods of processing recombinant procollagen |
| WO2009069123A2 (en) * | 2007-11-26 | 2009-06-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions comprising fibrous polypeptides and polysaccharides |
| ES2565185T3 (es) * | 2008-04-18 | 2016-04-01 | Collplant Ltd. | Métodos de generación y de uso del procolágeno |
| WO2011064773A1 (en) | 2009-11-24 | 2011-06-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2640877A2 (en) | 2010-11-16 | 2013-09-25 | Collplant Ltd. | Collagen structures and method of fabricating the same |
| WO2013030840A2 (en) | 2011-09-01 | 2013-03-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Adhesive biopolymers and uses thereof |
| WO2013093921A1 (en) | 2011-12-20 | 2013-06-27 | Collplant Ltd. | Collagen coated synthetic polymer fibers |
| KR102063686B1 (ko) * | 2012-01-02 | 2020-02-11 | (주)아모레퍼시픽 | 콩뿌리 추출물을 함유하는 피부 외용제 조성물 |
| EP2976097B1 (en) | 2013-03-21 | 2021-05-26 | CollPlant Ltd. | Compositions comprising collagen and prp for tissue regeneration and their production method |
| WO2014146175A1 (en) * | 2013-03-21 | 2014-09-25 | Commonwealth Scientific And Industrial Research Organisation | Purification of triple helical proteins |
| GB201308120D0 (en) * | 2013-05-06 | 2013-06-12 | Baden Wuerttemberg Stiftung Gmbh | Recombinant protein and method for its production |
| EP3044233A4 (en) | 2013-09-09 | 2017-07-19 | Commonwealth Scientific and Industrial Research Organisation | Modified bacterial collagen-like proteins |
| EP3221455B1 (en) | 2014-11-20 | 2020-08-12 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells |
| EP3634512A4 (en) | 2017-06-09 | 2021-04-14 | CollPlant Ltd. | GENERATIVE MANUFACTURING USING A RECOMBINANT COLLAGEN-CONTAINING FORMULATION |
| US20210032311A1 (en) * | 2017-09-25 | 2021-02-04 | Yu-Chun Wu | Non-human gene-edited mammal, protein crude extract separated from connective tissue of non-human gene-edited mammal, method for protein crude extract and uses of protein crude extract |
| AU2019263122B2 (en) | 2018-05-03 | 2022-09-29 | Collplant Ltd. | Dermal fillers and applications thereof |
| US20210310082A1 (en) * | 2018-07-31 | 2021-10-07 | Collplant Ltd. | Tobacco transgenic event and methods for detection and use thereof |
| CN109988234A (zh) * | 2019-02-20 | 2019-07-09 | 江苏悦智生物医药有限公司 | 酵母重组人源I型胶原α1链蛋白、合成方法及其应用 |
| EP4057833A1 (en) * | 2019-11-11 | 2022-09-21 | Kamcharov, Alexander Evgenievich | Beverage with collagen and additional additives |
| FR3105792B1 (fr) | 2019-12-26 | 2022-08-12 | Michel Assor | Matériau biocomposite collagène/matrice polymérique poreuse et son utilisation comme implant de réparation de lésions méniscales du genou et/ou de prévention ou de traitement de l’arthrose du genou |
| WO2021229577A1 (en) | 2020-05-12 | 2021-11-18 | Collplant Ltd. | Collagen as a delivery tool for metal-based anti-viral agents |
| KR20240169060A (ko) | 2022-04-04 | 2024-12-02 | 스위프트파마 비브이 | 식물에서 생산된 재조합 거미줄 강화 콜라겐 단백질 및 이의 용도 |
| CN119604615A (zh) | 2022-08-02 | 2025-03-11 | 株式会社UniBio | 胶原蛋白产生方法 |
| CN117209592A (zh) * | 2023-07-26 | 2023-12-12 | 浙江大学 | 一种人源化i型胶原蛋白及其制备方法与应用 |
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| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
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| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
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| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
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| GB8608850D0 (en) | 1986-04-11 | 1986-05-14 | Diatech Ltd | Packaging system |
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| ES2060646T3 (es) | 1987-02-09 | 1994-12-01 | Lubrizol Genetics Inc | Virus rna hibrido. |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US5693507A (en) | 1988-09-26 | 1997-12-02 | Auburn University | Genetic engineering of plant chloroplasts |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
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| FR2757874B1 (fr) | 1996-12-17 | 2003-04-25 | Biocem | Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations |
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| AU2003203147B2 (en) * | 1998-03-23 | 2008-05-29 | Novozymes A/S | Phytase variants |
| WO2001029242A2 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| HK1046003B (en) * | 1999-11-12 | 2008-02-06 | Fibrogen, Inc. | Bovine collagen and method for producing recombinant gelatin |
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| WO2002099067A2 (en) * | 2001-06-05 | 2002-12-12 | Oishi Karen K | Gene expression and production of tgf-b proteins including bioactive mullerian inhibiting substance from plants |
| WO2004057001A2 (en) * | 2002-12-19 | 2004-07-08 | University Of Bristol | Method for the production of polyunsaturated fatty acids |
| AU2003293906A1 (en) * | 2002-12-20 | 2004-07-22 | Basf Aktiengesellschaft | Malate dehydrogenase as a target for herbicides |
| JP5100386B2 (ja) | 2004-09-29 | 2012-12-19 | コルプラント リミテッド | コラーゲン生産植物及びその作成方法及びその使用 |
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- 2005-09-28 EP EP14185576.7A patent/EP2816117B1/en not_active Revoked
- 2005-09-28 NZ NZ554787A patent/NZ554787A/en not_active IP Right Cessation
- 2005-09-28 KR KR1020077009817A patent/KR20070083870A/ko not_active Withdrawn
- 2005-09-28 EP EP10181115A patent/EP2360261A1/en not_active Ceased
- 2005-09-28 EP EP16171177.5A patent/EP3088528B1/en active Active
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