DE60331690D1 - Zur gattung streptomyces gehörender, zur produktion von nemadictin fähiger stamm und verfahren zur produktion von nemadictin unter verwendung des stamms - Google Patents

Zur gattung streptomyces gehörender, zur produktion von nemadictin fähiger stamm und verfahren zur produktion von nemadictin unter verwendung des stamms

Info

Publication number
DE60331690D1
DE60331690D1 DE60331690T DE60331690T DE60331690D1 DE 60331690 D1 DE60331690 D1 DE 60331690D1 DE 60331690 T DE60331690 T DE 60331690T DE 60331690 T DE60331690 T DE 60331690T DE 60331690 D1 DE60331690 D1 DE 60331690D1
Authority
DE
Germany
Prior art keywords
nemadictin
streptomyces
stem
strain
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60331690T
Other languages
English (en)
Inventor
Satoshi Omura
Haruo Ikeda
Yumiko Ogasawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Application granted granted Critical
Publication of DE60331690D1 publication Critical patent/DE60331690D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60331690T 2003-06-11 2003-06-11 Zur gattung streptomyces gehörender, zur produktion von nemadictin fähiger stamm und verfahren zur produktion von nemadictin unter verwendung des stamms Expired - Lifetime DE60331690D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2003/007407 WO2004111230A1 (ja) 2003-06-11 2003-06-11 ストレプトマイセス属に属するネマデクチン生産能を有する菌株、該菌株を用いるネマデクチンの製造法

Publications (1)

Publication Number Publication Date
DE60331690D1 true DE60331690D1 (de) 2010-04-22

Family

ID=33548991

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60331690T Expired - Lifetime DE60331690D1 (de) 2003-06-11 2003-06-11 Zur gattung streptomyces gehörender, zur produktion von nemadictin fähiger stamm und verfahren zur produktion von nemadictin unter verwendung des stamms

Country Status (7)

Country Link
US (1) US7670827B2 (de)
EP (1) EP1632569B1 (de)
JP (1) JP4310750B2 (de)
CN (2) CN101372681B (de)
AU (1) AU2003244109B2 (de)
DE (1) DE60331690D1 (de)
WO (1) WO2004111230A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102952832B (zh) * 2011-08-23 2014-12-17 北大方正集团有限公司 一种发酵生产尼莫克汀的方法
CN104745654B (zh) * 2013-12-27 2017-09-22 牡丹江佰佳信生物科技有限公司 一种制备尼莫克汀的方法及其生产菌株
CN106916834B (zh) * 2015-12-24 2022-08-05 武汉合生科技有限公司 化合物的生物合成基因簇及其应用
CN110387390B (zh) * 2019-06-27 2021-06-01 华东理工大学青岛创新研究院 发酵培养基及发酵工艺
WO2021214588A1 (en) 2020-04-21 2021-10-28 Janssen Biotech, Inc. Anti-tnf alpha agent for treating coronavirus infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169956A (en) * 1984-06-05 1992-12-08 American Cyanamid Company Macrolide antibiotic compounds
US5106994A (en) * 1984-06-05 1992-04-21 American Cyanamid Company Agents and method of production thereof
US5312753A (en) 1992-03-23 1994-05-17 Merck & Co., Inc. Strain of streptomyces avermitilis capable of glycosylating avermectin compounds at the 13- and 14A positions
DK0637244T3 (da) * 1992-03-23 2001-01-29 Merck & Co Inc En stamme af Streptomyces avermilitis glycosylerer avermectinforbindelser
JP2003033188A (ja) 2001-05-14 2003-02-04 Kyowa Hakko Kogyo Co Ltd エバーメクチン誘導体の製造法
EP1477563A3 (de) * 2003-05-16 2004-11-24 Wyeth Klonierung von Streptomyces cyaneogriseus subsp.noncyanogenus Genen zur Biosynthese von Antibiotika und Verfahren zu ihrer Verwendung

Also Published As

Publication number Publication date
EP1632569B1 (de) 2010-03-10
CN101372681B (zh) 2011-09-07
US7670827B2 (en) 2010-03-02
US20060234353A1 (en) 2006-10-19
JP4310750B2 (ja) 2009-08-12
AU2003244109B2 (en) 2006-05-11
CN1714149A (zh) 2005-12-28
CN100429308C (zh) 2008-10-29
WO2004111230A1 (ja) 2004-12-23
JPWO2004111230A1 (ja) 2006-07-27
EP1632569A1 (de) 2006-03-08
AU2003244109A1 (en) 2005-01-04
EP1632569A4 (de) 2006-08-23
CN101372681A (zh) 2009-02-25

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DE60331690D1 (de) Zur gattung streptomyces gehörender, zur produktion von nemadictin fähiger stamm und verfahren zur produktion von nemadictin unter verwendung des stamms
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Legal Events

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