ZA200702066B - Halogenated benzmide derivatives - Google Patents
Halogenated benzmide derivativesInfo
- Publication number
- ZA200702066B ZA200702066B ZA200702066A ZA200702066A ZA200702066B ZA 200702066 B ZA200702066 B ZA 200702066B ZA 200702066 A ZA200702066 A ZA 200702066A ZA 200702066 A ZA200702066 A ZA 200702066A ZA 200702066 B ZA200702066 B ZA 200702066B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzmide
- halogenated
- derivatives
- halogenated benzmide
- benzmide derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60835404P | 2004-09-09 | 2004-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200702066B true ZA200702066B (en) | 2008-08-27 |
Family
ID=36060542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200702066A ZA200702066B (en) | 2004-09-09 | 2005-09-06 | Halogenated benzmide derivatives |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US7285567B2 (ja) |
| EP (1) | EP1789040B1 (ja) |
| JP (1) | JP4998852B2 (ja) |
| KR (1) | KR101344984B1 (ja) |
| CN (1) | CN101035531B (ja) |
| AP (1) | AP2451A (ja) |
| AU (1) | AU2005285157B2 (ja) |
| BR (1) | BRPI0515089B8 (ja) |
| CA (1) | CA2580347C (ja) |
| CY (1) | CY1118689T1 (ja) |
| DK (1) | DK1789040T3 (ja) |
| EA (1) | EA012606B1 (ja) |
| ES (1) | ES2559672T3 (ja) |
| HK (1) | HK1106139A1 (ja) |
| HR (1) | HRP20151439T1 (ja) |
| HU (1) | HUE026613T2 (ja) |
| IL (2) | IL181849A (ja) |
| ME (1) | ME02370B (ja) |
| MX (1) | MX2007002969A (ja) |
| PL (1) | PL1789040T3 (ja) |
| PT (1) | PT1789040E (ja) |
| RS (1) | RS54453B1 (ja) |
| SI (1) | SI1789040T1 (ja) |
| UA (1) | UA90864C2 (ja) |
| WO (1) | WO2006031566A2 (ja) |
| ZA (1) | ZA200702066B (ja) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ533865A (en) * | 2002-02-12 | 2006-02-24 | Smithkline Beecham Corp | Nicotinamide derivates useful as p38 inhibitors |
| UA90864C2 (en) * | 2004-09-09 | 2010-06-10 | Ромарк Лебораториз, Л.К. | Halogenated benzamide derivatives |
| US20070015803A1 (en) * | 2005-04-12 | 2007-01-18 | Romark Laboratories L.C. | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents |
| MX2008008723A (es) * | 2006-01-09 | 2008-09-26 | Romark Lab Lc | Tratamiento de la hepatitis viral. |
| JP5676258B2 (ja) | 2007-08-03 | 2015-02-25 | ロマーク ラボラトリース，エル．シー． | アルキルスルホニル置換チアゾリド化合物 |
| US8524278B2 (en) | 2009-02-13 | 2013-09-03 | Romark Laboratories L.C. | Controlled release pharmaceutical formulations of nitazoxanide |
| JP5918124B2 (ja) | 2009-05-12 | 2016-05-18 | ロマーク ラボラトリーズ エル．シー． | ハロアルキルヘテロアリールベンズアミド化合物 |
| MX341877B (es) | 2009-06-26 | 2016-09-06 | Romark Laboratories L C * | Compuestos y métodos para tratar influenza. |
| CN102335171B (zh) * | 2010-07-27 | 2013-09-11 | 中国农业科学院上海兽医研究所 | 一类n-(2-噻唑)苯甲酰胺衍生物的应用 |
| BR112013029505A2 (pt) | 2011-05-16 | 2020-01-07 | Romark Laboratories L.C. | Composição farmacêutica, e, uso de um composto |
| US9650369B2 (en) * | 2012-09-28 | 2017-05-16 | Xavier University Of Louisiana | Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease |
| JP6633092B2 (ja) | 2014-11-11 | 2020-01-22 | ロマーク ラボラトリーズ，リミティド カンパニー | チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法 |
| PT3436074T (pt) | 2016-03-31 | 2020-08-21 | Romark Laboratories Lc | Compostos tiazolida para tratamento de infeções virais |
| SI3442580T1 (sl) | 2016-04-11 | 2021-01-29 | Genfit | Metode zdravljenja holestatičnih in fibrotičnih bolezni |
| US11173149B2 (en) | 2017-04-18 | 2021-11-16 | Romark Laboratories L.C. | Inhibition of protein disulfide-isomerase A3 |
| WO2022020243A1 (en) | 2020-07-20 | 2022-01-27 | Romark Laboratories L.C. | Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine |
| AU2021333566A1 (en) | 2020-08-24 | 2023-03-16 | Romark Laboratories L.C. | Use of thiazolides against coronaviruses |
| WO2022218239A1 (zh) * | 2021-04-12 | 2022-10-20 | 杜心赟 | 新型噻唑类化合物及其制备方法和用途 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1276663A (en) * | 1968-12-24 | 1972-06-07 | Ici Ltd | Stimulation of plant growth |
| ZA712295B (en) * | 1970-04-15 | 1972-01-26 | Shell Int Research | Fungicidal compounds |
| GB1437800A (en) | 1973-08-08 | 1976-06-03 | Phavic Sprl | Derivatives of 2-benzamido-5-nitro-thiazoles |
| US4315018A (en) | 1978-12-07 | 1982-02-09 | Rossignol Jean F | Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives |
| JPS60205454A (ja) * | 1984-03-29 | 1985-10-17 | Mitsubishi Paper Mills Ltd | 電子写真感光体 |
| US5169846A (en) | 1989-10-12 | 1992-12-08 | Crooks Michael J | Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators |
| US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
| SK281949B6 (sk) * | 1994-04-13 | 2001-09-11 | Jean-Francois Rossignol | Derivát benzamidu, farmaceutický prostriedok, ktorý ho obsahuje, a použitie |
| US5578621A (en) | 1994-09-08 | 1996-11-26 | Romark Lab Lc | Benzamide derivatives |
| US5387598A (en) | 1994-04-13 | 1995-02-07 | Rossignol; Jean-Francois | Composition and galenic formulation suitable for combatting affections of the lower abdomen |
| US5965590A (en) | 1994-09-08 | 1999-10-12 | Romark Lab Lc | Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide |
| US5859038A (en) | 1994-09-08 | 1999-01-12 | Romark Laboratories, L.C. | Method for treatment of helicobacter pylori infections |
| US5968961A (en) | 1997-05-07 | 1999-10-19 | Romark Laboratories, L.C. | Pharmaceutical compositions of tizoxanide and nitazoxanide |
| MX9604483A (es) | 1994-09-08 | 1998-02-28 | Jean-Francois Rossignol | Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas. |
| US5856348A (en) | 1994-09-08 | 1999-01-05 | Romark Laboratories, L.C. | Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide |
| DE19528046A1 (de) * | 1994-11-21 | 1996-05-23 | Bayer Ag | Triazolyl-Derivate |
| US5935591A (en) * | 1998-01-15 | 1999-08-10 | Romark Laboratories, L.C. | Method for treatment of equine protozoal myeloencephalitis with thiazolides |
| GB9823871D0 (en) * | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
| IL152451A0 (en) * | 2000-04-28 | 2003-05-29 | Sankyo Co | 2-chloro-2-nitrophenylcarboxamide derivatives and pharmaceutical compositions containing the same |
| EP1301378A1 (en) * | 2000-07-14 | 2003-04-16 | Breed Automotive Technology, Inc. | Energy absorbing seat belt retractor |
| EP1844766B1 (en) | 2000-12-18 | 2012-04-18 | Institute of Medicinal Molecular Design, Inc. | Inhibitors against the production and release of inflammatory cytokines |
| JP2003064056A (ja) * | 2001-08-27 | 2003-03-05 | Sankyo Co Ltd | アミド誘導体 |
| WO2003035602A1 (fr) * | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Modulateurs lipidiques |
| WO2003103665A1 (ja) * | 2002-06-06 | 2003-12-18 | 株式会社医薬分子設計研究所 | 抗アレルギー薬 |
| US6737382B1 (en) * | 2002-10-23 | 2004-05-18 | Nippon Soda Co. Ltd. | Insecticidal aminothiazole derivatives |
| AU2005206571B8 (en) * | 2004-01-23 | 2010-09-02 | Amgen Inc. | Compounds and methods of use |
| UA90864C2 (en) * | 2004-09-09 | 2010-06-10 | Ромарк Лебораториз, Л.К. | Halogenated benzamide derivatives |
-
2005
- 2005-06-09 UA UAA200702713A patent/UA90864C2/ru unknown
- 2005-09-06 CA CA2580347A patent/CA2580347C/en not_active Expired - Fee Related
- 2005-09-06 PL PL05800142T patent/PL1789040T3/pl unknown
- 2005-09-06 WO PCT/US2005/031868 patent/WO2006031566A2/en active Application Filing
- 2005-09-06 CN CN2005800338784A patent/CN101035531B/zh not_active Expired - Fee Related
- 2005-09-06 PT PT58001421T patent/PT1789040E/pt unknown
- 2005-09-06 AU AU2005285157A patent/AU2005285157B2/en not_active Ceased
- 2005-09-06 DK DK05800142.1T patent/DK1789040T3/en active
- 2005-09-06 EA EA200700432A patent/EA012606B1/ru not_active IP Right Cessation
- 2005-09-06 ES ES05800142.1T patent/ES2559672T3/es active Active
- 2005-09-06 MX MX2007002969A patent/MX2007002969A/es active IP Right Grant
- 2005-09-06 SI SI200532034T patent/SI1789040T1/sl unknown
- 2005-09-06 US US11/221,256 patent/US7285567B2/en active Active
- 2005-09-06 AP AP2007003950A patent/AP2451A/xx active
- 2005-09-06 EP EP05800142.1A patent/EP1789040B1/en active Active
- 2005-09-06 ZA ZA200702066A patent/ZA200702066B/xx unknown
- 2005-09-06 RS RS20160058A patent/RS54453B1/en unknown
- 2005-09-06 JP JP2007531304A patent/JP4998852B2/ja not_active Expired - Fee Related
- 2005-09-06 BR BRPI0515089A patent/BRPI0515089B8/pt not_active IP Right Cessation
- 2005-09-06 ME MEP-2016-7A patent/ME02370B/me unknown
- 2005-09-06 HU HUE05800142A patent/HUE026613T2/hu unknown
-
2007
- 2007-03-11 IL IL181849A patent/IL181849A/en not_active IP Right Cessation
- 2007-03-29 KR KR1020077007159A patent/KR101344984B1/ko active IP Right Grant
- 2007-10-01 US US11/865,541 patent/US7550493B2/en active Active
- 2007-10-01 US US11/865,532 patent/US7645783B2/en active Active
- 2007-10-24 HK HK07111470.9A patent/HK1106139A1/zh not_active IP Right Cessation
-
2009
- 2009-12-29 IL IL203061A patent/IL203061A/en active IP Right Grant
-
2015
- 2015-12-30 HR HRP20151439TT patent/HRP20151439T1/hr unknown
-
2016
- 2016-01-20 CY CY20161100061T patent/CY1118689T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA200702066B (en) | Halogenated benzmide derivatives | |
| TWI369356B (en) | Tetrahydropyridoindole derivatives | |
| IL180481A0 (en) | Aryl-pyridine derivatives | |
| HK1105971A1 (en) | Pyrrazolo-pyrimidine derivatives | |
| IL179603A0 (en) | Pyrrolopyridine derivatives | |
| AP2074A (en) | New 4-benzylidene-piperidin derivatives | |
| IL183140A0 (en) | Substituted benzoquinolizine derivatives | |
| ZA200703172B (en) | Imidazo-benzodiazepine derivatives | |
| IL177204A0 (en) | Novel 4-benzimidazol -2-ylpyridazin -3- one derivatives | |
| HK1101638A1 (en) | New pyridothienopyrimidine derivatives | |
| HK1100002A1 (en) | 4-phenyl-pyrimidine-2-carbonitrile derivatives | |
| HK1100775A1 (en) | 4-Amino-5-cyanopyrimidine derivatives | |
| GB0414272D0 (en) | OsK1 derivatives | |
| IL182001A0 (en) | 2-acylaminothiazole derivatives | |
| ZA200609864B (en) | Pyrrolopyridine derivatives | |
| GB0405905D0 (en) | Azaquinazoline derivatives | |
| GB0422397D0 (en) | 3-Cyano-Quinoline derivatives | |
| HUP0402371A2 (en) | Novel 125-i-labeled amino-quinoline derivatives |