ZA200609008B - Methods for the preparation of (3R, 3aS, 6aR) hexahydrofuro[2,3-b]furan-3-ol - Google Patents

Methods for the preparation of (3R, 3aS, 6aR) hexahydrofuro[2,3-b]furan-3-ol

Info

Publication number
ZA200609008B
ZA200609008B ZA200609008A ZA200609008A ZA200609008B ZA 200609008 B ZA200609008 B ZA 200609008B ZA 200609008 A ZA200609008 A ZA 200609008A ZA 200609008 A ZA200609008 A ZA 200609008A ZA 200609008 B ZA200609008 B ZA 200609008B
Authority
ZA
South Africa
Prior art keywords
hexahydrofuro
furan
preparation
methods
Prior art date
Application number
ZA200609008A
Other languages
English (en)
Inventor
Quaedflieg Peter Jan Leonold Mario
Kesteleyn Bart Rudolf Romanie
Vijn Robert Jan
Liebregts Constantinus Simon Maria
Kooistra Jacob Hermanus Matheus Hero
Lommen Franciscus Alphons Marie
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34928933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200609008(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of ZA200609008B publication Critical patent/ZA200609008B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
ZA200609008A 2004-03-31 2006-10-30 Methods for the preparation of (3R, 3aS, 6aR) hexahydrofuro[2,3-b]furan-3-ol ZA200609008B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04101336 2004-03-31

Publications (1)

Publication Number Publication Date
ZA200609008B true ZA200609008B (en) 2008-07-30

Family

ID=34928933

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200609008A ZA200609008B (en) 2004-03-31 2006-10-30 Methods for the preparation of (3R, 3aS, 6aR) hexahydrofuro[2,3-b]furan-3-ol

Country Status (28)

Country Link
US (1) US7595408B2 (xx)
EP (1) EP1732931B1 (xx)
JP (1) JP4778955B2 (xx)
KR (1) KR101135156B1 (xx)
CN (1) CN1938316B (xx)
AP (1) AP2528A (xx)
AU (1) AU2005229435B2 (xx)
BR (1) BRPI0509514B1 (xx)
CA (1) CA2559959C (xx)
CY (1) CY1119150T1 (xx)
DK (1) DK1732931T3 (xx)
ES (1) ES2587571T3 (xx)
HR (1) HRP20161031T1 (xx)
HU (1) HUE029886T2 (xx)
IL (1) IL178019A (xx)
LT (1) LT1732931T (xx)
ME (1) ME02525B (xx)
NO (1) NO338175B1 (xx)
NZ (1) NZ549971A (xx)
PL (1) PL1732931T3 (xx)
PT (1) PT1732931T (xx)
RS (1) RS55011B1 (xx)
RU (1) RU2421458C2 (xx)
SI (1) SI1732931T1 (xx)
TW (1) TWI383975B (xx)
UA (1) UA100835C2 (xx)
WO (1) WO2005095410A1 (xx)
ZA (1) ZA200609008B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2089371T3 (da) 2006-11-09 2011-05-16 Tibotec Pharm Ltd Fremstillingsmåde til fremstilling af hexahydrofuro[2,3-b]furan-3-OL
CN101024646B (zh) * 2007-02-06 2010-07-14 启东东岳药业有限公司 4-甲氧基呋喃并呋喃-2-酮的纯化方法
PT2152667E (pt) 2007-04-27 2011-04-06 Tibotec Pharm Ltd Processos para a preparação de derivados de n-isobutil-n- (2-hidroxi-3-amino-4-fenilbutil)-p-nitrobenzenosulfonilamida
WO2009030733A1 (en) * 2007-09-04 2009-03-12 Dsm Ip Assets B.V. Method for the synthesis of 4-alkoxy-, 4-hydroxy- and 4-aryloxy-substituted tetrahydro-furo[3,4-b]furan-2(3h)-one compounds
CA2747168A1 (en) 2008-12-03 2010-10-21 Massachusetts Institute Of Technology Multifunctional composites based on coated nanostructures
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
WO2011051978A2 (en) 2009-10-30 2011-05-05 Lupin Limited A novel process for preparation of darunavir and darunavir ethanolate of fine particle size
WO2011092687A1 (en) 2010-01-28 2011-08-04 Mapi Pharma Hk Limited Process for the preparation of darunavir and darunavir intermediates
EP2877474B1 (en) 2012-07-24 2020-11-04 Laurus Labs Limited A process for preparation of darunavir
CN103864813B (zh) * 2012-12-18 2017-02-22 上海迪赛诺化学制药有限公司 一种合成六氢呋喃并[2,3‑b]呋喃‑3‑醇及其对映体的方法
CN104628552A (zh) * 2015-02-09 2015-05-20 许昌豪丰化学科技有限公司 一种新淬灭体系及其应用
WO2017041228A1 (zh) * 2015-09-08 2017-03-16 浙江九洲药业股份有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法
ES2881949T3 (es) 2016-10-27 2021-11-30 Gilead Sciences Inc Forma cristalina de base libre de darunavir
CN116103348A (zh) 2018-03-16 2023-05-12 江苏瑞科医药科技有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法
WO2020168348A1 (en) 2019-02-15 2020-08-20 Digilens Inc. Methods and apparatuses for providing a holographic waveguide display using integrated gratings
CN115557964A (zh) * 2022-10-18 2023-01-03 启东东岳药业有限公司 一种药物化合物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427693A1 (en) * 1989-10-11 1991-05-15 Monsanto Company Method for azide displacement of alpha-triflates of 1,5-lactones
EP0715618B1 (en) 1993-08-24 1998-12-16 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
US6127372A (en) 1994-03-07 2000-10-03 Vertex Pharmaceuticals, Incorporated Sulfonamide inhibitors of aspartyl protease
PT1086076E (pt) 1998-06-19 2005-05-31 Vertex Pharma Inibidores de sulfonamida de aspartil protease
EP2336134B1 (en) 1998-06-23 2016-08-31 The United States of America, represented by the Secretary, Department of Health and Human Services Fitness assay and methods for reducing resistance of HIV to therapy
WO2000047551A2 (en) 1999-02-12 2000-08-17 Vertex Pharmaceuticals Incorporated Inhibitors of aspartyl protease
AR031520A1 (es) 1999-06-11 2003-09-24 Vertex Pharma Un compuesto inhibidor de aspartilo proteasa, una composicion que lo comprende y un metodo para tratar un paciente con dicha composicion
PL204924B1 (pl) 1999-10-06 2010-02-26 Tibotec Pharm Ltd Heksahydrofuro [2,3-b] furanylo-3-N-{3(1,3-benzodioksolilo-5-sulfonylo) (izobutylo) amino] -1-benzylo-2-hydroksypropylo} karbaminian oraz jego zastosowanie
EP1448567B1 (en) * 2001-09-10 2009-12-30 Tibotec Pharmaceuticals Method for the preparation of hexahydro-furo 2,3-b furan-3-ol

Also Published As

Publication number Publication date
DK1732931T3 (en) 2016-08-29
PL1732931T3 (pl) 2016-11-30
PT1732931T (pt) 2016-07-14
NO20064977L (no) 2006-10-31
ES2587571T3 (es) 2016-10-25
BRPI0509514A8 (pt) 2016-02-10
ME02525B (me) 2017-02-20
AU2005229435B2 (en) 2011-07-07
CA2559959A1 (en) 2005-10-13
KR101135156B1 (ko) 2012-04-23
AP2528A (en) 2012-12-10
BRPI0509514A (pt) 2007-09-11
NO338175B1 (no) 2016-08-01
RU2006138228A (ru) 2008-05-10
RS55011B1 (sr) 2016-11-30
EP1732931A1 (en) 2006-12-20
AP2006003748A0 (en) 2006-10-31
IL178019A0 (en) 2006-12-31
AU2005229435A1 (en) 2005-10-13
US7595408B2 (en) 2009-09-29
UA100835C2 (ru) 2013-02-11
NZ549971A (en) 2010-12-24
JP4778955B2 (ja) 2011-09-21
RU2421458C2 (ru) 2011-06-20
JP2007530638A (ja) 2007-11-01
KR20070026479A (ko) 2007-03-08
HUE029886T2 (en) 2017-04-28
TW200602346A (en) 2006-01-16
CN1938316A (zh) 2007-03-28
US20070208184A1 (en) 2007-09-06
IL178019A (en) 2014-02-27
BRPI0509514B1 (pt) 2022-09-27
HRP20161031T1 (hr) 2016-10-21
CA2559959C (en) 2013-11-19
TWI383975B (zh) 2013-02-01
EP1732931B1 (en) 2016-05-18
CN1938316B (zh) 2012-12-12
LT1732931T (lt) 2016-09-12
WO2005095410A1 (en) 2005-10-13
SI1732931T1 (sl) 2016-10-28
CY1119150T1 (el) 2018-01-10

Similar Documents

Publication Publication Date Title
ZA200609008B (en) Methods for the preparation of (3R, 3aS, 6aR) hexahydrofuro[2,3-b]furan-3-ol
IL194122A (en) Process for making (6ar, 3as, 3r) hexahydroporo [3,2– b] furan – 3 – val
WO2008055970A3 (en) Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol
IL160166A0 (en) Method for the preparation of hexahydro-furo[2,3-b] furan-3-ol
IL211191A (en) Oxalate salt of (3as, 4r, 6s, 6ar) –6– (2– hydroxyethoxy) –2,2 – dimethyl tetrahydro –3 ah– cyclopenta [d] [1,3] dioxol – 4 – amine
ZA201202025B (en) INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLO[2,3-b] PYRIDINE DERIVATIVES
ME01059B (me) Proces za pripremanje (3r,3as,6ar)-heksahidrofuro [2,3-b] furan-3-il (1s,2r)-3-[[(4-aminofenil) sulfonil] (izobutil) amino]-1-benzil-2- hidroksipropilkarbamata
ZA200708490B (en) Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a, 12b-tetrahydro-1H-dibenz[2,3:6,7] oxepino[4,5-c]pyrrole
AU2003287038A8 (en) Method of preparing (3r, 3as, 6ar) -3- hydroxyhexahydrofuro (2, 3-b) furan and related compounds
PL1678182T3 (pl) Sposób wytwarzania podstawionych 5-aminopirazolo[4,3-e]-1,2,4-triazolo-[1,5-c]pirymidyn
DK1784403T3 (da) Pyrrolo[3,2-b]pyridinderivater samt fremgangsmåder til deres fremstilling
PT2643326T (pt) Processo para a preparação de (3r,3as,6ar)-hexa-hidrofuro[2,3-b]furan-3-ol