ZA200607850B - Use of PPAR delta agonists for treating demyelinating diseases - Google Patents

Use of PPAR delta agonists for treating demyelinating diseases

Info

Publication number
ZA200607850B
ZA200607850B ZA200607850A ZA200607850A ZA200607850B ZA 200607850 B ZA200607850 B ZA 200607850B ZA 200607850 A ZA200607850 A ZA 200607850A ZA 200607850 A ZA200607850 A ZA 200607850A ZA 200607850 B ZA200607850 B ZA 200607850B
Authority
ZA
South Africa
Prior art keywords
demyelinating diseases
ppar delta
delta agonists
treating demyelinating
treating
Prior art date
Application number
ZA200607850A
Other languages
English (en)
Inventor
Chandross Karen
Minnich Anne
Khorkova Olga
Merrill Jean
Lee Lan
Liu Yun
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of ZA200607850B publication Critical patent/ZA200607850B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200607850A 2004-04-01 2006-09-19 Use of PPAR delta agonists for treating demyelinating diseases ZA200607850B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55853304P 2004-04-01 2004-04-01

Publications (1)

Publication Number Publication Date
ZA200607850B true ZA200607850B (en) 2008-10-29

Family

ID=34977094

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200607850A ZA200607850B (en) 2004-04-01 2006-09-19 Use of PPAR delta agonists for treating demyelinating diseases

Country Status (16)

Country Link
US (1) US20070149580A1 (xx)
EP (1) EP1737440A2 (xx)
JP (1) JP2007530703A (xx)
KR (1) KR20060134191A (xx)
CN (1) CN1950077A (xx)
AU (1) AU2005231358A1 (xx)
BR (1) BRPI0509540A (xx)
CA (1) CA2561159A1 (xx)
IL (1) IL178165A0 (xx)
MA (1) MA28561B1 (xx)
MX (1) MXPA06011218A (xx)
NO (1) NO20064985L (xx)
RU (1) RU2006138495A (xx)
SG (1) SG138623A1 (xx)
WO (1) WO2005097098A2 (xx)
ZA (1) ZA200607850B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486055T1 (de) 2004-05-05 2010-11-15 High Point Pharmaceuticals Llc Neue verbindungen, ihre herstellung und verwendung
JP4981662B2 (ja) 2004-05-05 2012-07-25 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 新規の化合物、その製法と使用
RU2412935C2 (ru) 2005-06-30 2011-02-27 Хай Пойнт Фармасьютикалс, ЛЛС Феноксиуксусные кислоты в качестве активаторов дельта рецепторов ppar
US8148389B2 (en) * 2005-11-28 2012-04-03 Senju Pharmaceutical Co., Ltd. Pharmaceutical comprising PPAR agonist
EP2386540A1 (en) 2005-12-22 2011-11-16 High Point Pharmaceuticals, LLC Novel compounds, their preparation and use
WO2007101864A2 (en) 2006-03-09 2007-09-13 High Point Pharmaceuticals, Llc Compounds that modulate ppar activity, their preparation and use
WO2010000353A1 (en) 2008-06-09 2010-01-07 Sanofi-Aventis Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
EP2288604B1 (en) 2008-06-09 2014-01-08 Sanofi Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
CN102639700A (zh) 2009-09-30 2012-08-15 哈佛大学校长及研究员协会 通过调节自噬增强基因产物调节自噬的方法
CA2784652A1 (en) 2009-12-17 2011-07-14 Sanofi Animal model expressing luciferase under control of the myelin basic protein promoter (mbp-luci) and use of the model for bioluminescence in vivo imaging
WO2012112933A1 (en) * 2011-02-18 2012-08-23 The Scripps Research Institute Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
CA2923422C (en) 2013-09-09 2021-09-07 Vtv Therapeutics Llc Use of a ppar-delta agonist for treating muscle atrophy
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1856997A (en) * 1996-02-02 1997-08-22 Merck & Co., Inc. Method for raising hdl cholesterol levels
GB9914977D0 (en) * 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
AU2001288271A1 (en) * 2000-08-17 2002-02-25 Harrihar A. Pershadsingh Methods for treating inflammatory diseases
GB0024362D0 (en) * 2000-10-05 2000-11-22 Glaxo Group Ltd Medicaments
GB0024361D0 (en) * 2000-10-05 2000-11-22 Glaxo Group Ltd Medicaments
US20050020654A1 (en) * 2003-03-15 2005-01-27 Pershadsingh Harrihar A. Novel PPAR agonists, pharmaceutical compositions and uses thereof
EP1637161A4 (en) * 2003-04-22 2007-06-27 Astellas Pharma Inc MEANS FOR THE TREATMENT OF NEURODEGENERATIVE ILLNESSES OF THE BRAIN WITH PPAR [delta] AGONIST

Also Published As

Publication number Publication date
KR20060134191A (ko) 2006-12-27
RU2006138495A (ru) 2008-05-10
WO2005097098A3 (en) 2005-12-22
WO2005097098A2 (en) 2005-10-20
CN1950077A (zh) 2007-04-18
US20070149580A1 (en) 2007-06-28
JP2007530703A (ja) 2007-11-01
CA2561159A1 (en) 2005-10-20
SG138623A1 (en) 2008-01-28
AU2005231358A1 (en) 2005-10-20
MXPA06011218A (es) 2007-01-16
MA28561B1 (fr) 2007-04-03
IL178165A0 (en) 2008-03-20
NO20064985L (no) 2006-10-31
BRPI0509540A (pt) 2007-09-18
EP1737440A2 (en) 2007-01-03

Similar Documents

Publication Publication Date Title
ZA200607850B (en) Use of PPAR delta agonists for treating demyelinating diseases
PL2001892T3 (pl) Imidazolotiazolowe związki do leczenia chorób proliferacyjnych
IL227841A0 (en) Dihydropyridinones for the treatment of cancer
HK1096083A1 (en) Sulfonamide derivatives for the treatment of diseases
AP2006003669A0 (en) Sulfonamide derivatives for the treatment of diseases
EP2063889A4 (en) SPIROPIPERIDINE BETA SEKRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER DISEASE
ZA200508427B (en) Methods for treating interleuking-6 related diseases
EP2063896A4 (en) KINASEHEMMER FOR THE TREATMENT OF PROLIFERATIVE DISEASES
PL1817282T3 (pl) Pochodne kwasu fenoksyoctowego użyteczne do leczenia chorób układu oddechowego
SI1706112T1 (sl) Postopki za zdravljenje vnetne bolezni
ATE542823T1 (de) 4,5-dihydro-ä1,2,4ütriazoloä4,3-füpteridine als plk1-proteinkinasehemmer zur behandlung proliferativer erkrankungen
IL187739A0 (en) New 2-azetidinone derivatives for the treatment of hyperlipidaemic diseases
EP1750513A4 (en) USE OF GPCR54 LIGANDS FOR THE TREATMENT OF INFERTILITY
PT2056804E (pt) Utilização de derivados de 2,5-di-hidroxibenzeno para o tratamento de doenças oculares
EP1701735A4 (en) METHODS AND COMPOSITIONS FOR USE IN THE TREATMENT OF DIABETES
EP1709155A4 (en) COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF DYSPROLIFERATIVE DISEASES AND METHODS OF THEIR USE
EP2039392A4 (en) DEVICE FOR PHYSIOTHERAPY TREATMENT OF DISEASES OF VARIOUS AITIOLOGIES
IL188894A0 (en) Compounds for treatment of lipase-mediated diseases
ZA200606780B (en) Compounds for the treatment of diseases
GB0428218D0 (en) Medicament for Treatment of Inflammatory Diseases
IL178990A0 (en) Methods of treating demyelinating disorders
IL175611A0 (en) Combinations for the treatment of proliferative diseases
AP2006003728A0 (en) Compounds for treatment of diseases
GB0420867D0 (en) Compounds for the treatment of diseases
GB0425064D0 (en) Compounds useful for the treatment of diseases