ZA200600421B - Indol-4 sulfonamide derivatives, their preparation and their use as 5-HT-6 modulators - Google Patents
Indol-4 sulfonamide derivatives, their preparation and their use as 5-HT-6 modulators Download PDFInfo
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- ZA200600421B ZA200600421B ZA200600421A ZA200600421A ZA200600421B ZA 200600421 B ZA200600421 B ZA 200600421B ZA 200600421 A ZA200600421 A ZA 200600421A ZA 200600421 A ZA200600421 A ZA 200600421A ZA 200600421 B ZA200600421 B ZA 200600421B
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Classifications
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
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ES200301807A ES2222829B1 (es) | 2003-07-30 | 2003-07-30 | Derivados de 4-indolilsulfonamidas, su preparacion y su aplicacion como medicamentos. |
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ZA200600421A ZA200600421B (en) | 2003-07-30 | 2004-07-29 | Indol-4 sulfonamide derivatives, their preparation and their use as 5-HT-6 modulators |
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US (1) | US8097643B2 (zh) |
EP (1) | EP1648446B1 (zh) |
JP (1) | JP2007500166A (zh) |
KR (1) | KR20060123698A (zh) |
CN (1) | CN100518736C (zh) |
AT (1) | ATE432700T1 (zh) |
AU (1) | AU2004262486A1 (zh) |
BR (1) | BRPI0413068A (zh) |
CA (1) | CA2534098A1 (zh) |
DE (1) | DE602004021385D1 (zh) |
EC (2) | ECSP066324A (zh) |
ES (2) | ES2222829B1 (zh) |
IL (1) | IL172892A0 (zh) |
MX (1) | MXPA06001137A (zh) |
NO (1) | NO20060155L (zh) |
NZ (1) | NZ545300A (zh) |
PE (1) | PE20050333A1 (zh) |
PT (1) | PT1648446E (zh) |
RU (1) | RU2006105778A (zh) |
TW (1) | TW200505855A (zh) |
WO (1) | WO2005013978A1 (zh) |
ZA (1) | ZA200600421B (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2007373A4 (en) * | 2006-03-29 | 2012-12-19 | Foldrx Pharmaceuticals Inc | INHIBITION OF ALPHA SYNUCLEINE TOXICITY |
DE102007007751A1 (de) * | 2007-02-16 | 2008-08-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
DE102007012284A1 (de) | 2007-03-16 | 2008-09-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
EP2018861A1 (en) * | 2007-07-26 | 2009-01-28 | Laboratorios del Dr. Esteve S.A. | 5HT6-Ligands such as sulfonamide derivatives in drug-induced weight-gain |
DE102007035333A1 (de) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
DE102007035334A1 (de) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel |
ES2358288T3 (es) | 2007-08-01 | 2011-05-09 | Laboratorios Del Dr. Esteve S.A. | Combinación de al menos dos ligandos de 5ht6. |
DE102007042154A1 (de) | 2007-09-05 | 2009-03-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel |
EP2053052A1 (en) | 2007-10-23 | 2009-04-29 | Laboratorios del Dr. Esteve S.A. | Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide |
JP5709743B2 (ja) * | 2008-06-06 | 2015-04-30 | ハーバー セラピューティクス, インコーポレイテッド | 17−アルキニル−7−ヒドロキシステロイドおよび関連する化合物の調製方法 |
US20190336585A1 (en) * | 2018-05-03 | 2019-11-07 | John Lawrence Mee | Method for sustainable human cognitive enhancement |
US20190390193A1 (en) * | 2018-06-23 | 2019-12-26 | John Lawrence Mee | Reversible method for sustainable human cognitive enhancement |
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US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
GB9317764D0 (en) * | 1993-08-26 | 1993-10-13 | Pfizer Ltd | Therapeutic compound |
NZ305166A (en) | 1995-03-20 | 1998-12-23 | Lilly Co Eli | 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles; preparation and medicaments |
US5939451A (en) * | 1996-06-28 | 1999-08-17 | Hoffmann-La Roche Inc. | Use of sulfonamides |
US6043706A (en) | 1999-02-05 | 2000-03-28 | Ericsson Inc. | Methods and apparatus for controlling power amplifier quiescent current in a wireless communication device |
GB9902459D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
US6521658B1 (en) * | 1999-05-28 | 2003-02-18 | Abbott Laboratories | Cell proliferation inhibitors |
GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
AU2002236730B2 (en) * | 2001-01-30 | 2006-06-15 | Eli Lilly And Company | Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-HT6 receptor |
ES2187300B1 (es) * | 2001-11-14 | 2004-06-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos. |
CA2524682A1 (en) * | 2003-05-09 | 2004-11-18 | Laboratorios Del Dr. Esteve S.A. | Use of sulphonamide derivatives for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
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2004
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- 2004-07-29 JP JP2006521530A patent/JP2007500166A/ja active Pending
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BRPI0413068A (pt) | 2006-10-17 |
NZ545300A (en) | 2008-05-30 |
US8097643B2 (en) | 2012-01-17 |
US20070185158A1 (en) | 2007-08-09 |
NO20060155L (no) | 2006-01-10 |
ES2327848T3 (es) | 2009-11-04 |
EP1648446A1 (en) | 2006-04-26 |
KR20060123698A (ko) | 2006-12-04 |
CN100518736C (zh) | 2009-07-29 |
ECSP066322A (es) | 2006-08-30 |
AU2004262486A1 (en) | 2005-02-17 |
CN1829508A (zh) | 2006-09-06 |
MXPA06001137A (es) | 2006-04-24 |
ECSP066324A (es) | 2006-08-30 |
CA2534098A1 (en) | 2005-02-17 |
WO2005013978A1 (en) | 2005-02-17 |
ES2222829A1 (es) | 2005-02-01 |
JP2007500166A (ja) | 2007-01-11 |
RU2006105778A (ru) | 2007-09-20 |
TW200505855A (en) | 2005-02-16 |
PT1648446E (pt) | 2009-09-03 |
EP1648446B1 (en) | 2009-06-03 |
PE20050333A1 (es) | 2005-06-12 |
DE602004021385D1 (de) | 2009-07-16 |
ATE432700T1 (de) | 2009-06-15 |
ES2222829B1 (es) | 2006-03-01 |
IL172892A0 (en) | 2006-06-11 |
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