ZA200509708B - Selective R-cadherin antagonists and methods - Google Patents

Selective R-cadherin antagonists and methods Download PDF

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Publication number
ZA200509708B
ZA200509708B ZA200509708A ZA200509708A ZA200509708B ZA 200509708 B ZA200509708 B ZA 200509708B ZA 200509708 A ZA200509708 A ZA 200509708A ZA 200509708 A ZA200509708 A ZA 200509708A ZA 200509708 B ZA200509708 B ZA 200509708B
Authority
ZA
South Africa
Prior art keywords
amino acid
xaa
peptide
cadherin
ser
Prior art date
Application number
ZA200509708A
Other languages
English (en)
Inventor
Friedlander Martin
Michael I Dorrell
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of ZA200509708B publication Critical patent/ZA200509708B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200509708A 2003-05-01 2005-11-30 Selective R-cadherin antagonists and methods ZA200509708B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46718803P 2003-05-01 2003-05-01

Publications (1)

Publication Number Publication Date
ZA200509708B true ZA200509708B (en) 2006-12-27

Family

ID=33435033

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200509708A ZA200509708B (en) 2003-05-01 2005-11-30 Selective R-cadherin antagonists and methods

Country Status (18)

Country Link
US (2) US7419953B2 (ko)
EP (1) EP1635855B1 (ko)
JP (1) JP4613300B2 (ko)
KR (2) KR101120419B1 (ko)
CN (2) CN103272219A (ko)
AT (1) ATE491718T1 (ko)
AU (1) AU2004236208B2 (ko)
BR (1) BRPI0409850A (ko)
CA (1) CA2523932A1 (ko)
DE (1) DE602004030565D1 (ko)
DK (1) DK1635855T3 (ko)
ES (1) ES2355260T3 (ko)
MX (1) MXPA05011751A (ko)
PL (1) PL1635855T3 (ko)
PT (1) PT1635855E (ko)
RU (1) RU2349598C2 (ko)
WO (1) WO2004099232A2 (ko)
ZA (1) ZA200509708B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277824B1 (en) * 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803904B2 (en) * 1995-09-01 2010-09-28 Millennium Pharmaceuticals, Inc. Mucosal vascular addressing and uses thereof
DE69637155T2 (de) * 1995-02-10 2008-02-07 Millennium Pharmaceuticals, Inc., Cambridge Addressine der schleimhaut und der blutgefässe und ihre verwendung
AU759144B2 (en) * 1998-05-05 2003-04-03 Adherex Technologies Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US6277824B1 (en) * 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
US20020151681A1 (en) * 1999-03-12 2002-10-17 Rosen Craig A. Nucleic acids, proteins and antibodies
WO2004085455A1 (en) * 2003-03-24 2004-10-07 The University Of Hong Kong A diagnostic assay for the human virus causing severe acute respiratory syndrome (sars)

Also Published As

Publication number Publication date
JP2006525344A (ja) 2006-11-09
US7419953B2 (en) 2008-09-02
BRPI0409850A (pt) 2006-05-09
CN1812804A (zh) 2006-08-02
EP1635855A4 (en) 2007-10-10
MXPA05011751A (es) 2006-02-17
EP1635855B1 (en) 2010-12-15
EP1635855A2 (en) 2006-03-22
CN1812804B (zh) 2013-06-12
WO2004099232A2 (en) 2004-11-18
ES2355260T3 (es) 2011-03-24
RU2005137322A (ru) 2006-06-10
US20050004013A1 (en) 2005-01-06
DE602004030565D1 (de) 2011-01-27
US8163697B2 (en) 2012-04-24
PL1635855T3 (pl) 2011-04-29
ATE491718T1 (de) 2011-01-15
US20090124538A1 (en) 2009-05-14
RU2349598C2 (ru) 2009-03-20
CN103272219A (zh) 2013-09-04
JP4613300B2 (ja) 2011-01-12
CA2523932A1 (en) 2004-11-18
PT1635855E (pt) 2011-02-23
DK1635855T3 (da) 2011-02-14
KR101138633B1 (ko) 2012-07-04
AU2004236208B2 (en) 2009-10-29
KR20110099065A (ko) 2011-09-05
WO2004099232A3 (en) 2005-05-19
KR101120419B1 (ko) 2012-03-16
AU2004236208A1 (en) 2004-11-18
KR20060009283A (ko) 2006-01-31

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