ZA200506286B - Therapeutic agent for hemorrhoidal disease - Google Patents
Therapeutic agent for hemorrhoidal disease Download PDFInfo
- Publication number
- ZA200506286B ZA200506286B ZA200506286A ZA200506286A ZA200506286B ZA 200506286 B ZA200506286 B ZA 200506286B ZA 200506286 A ZA200506286 A ZA 200506286A ZA 200506286 A ZA200506286 A ZA 200506286A ZA 200506286 B ZA200506286 B ZA 200506286B
- Authority
- ZA
- South Africa
- Prior art keywords
- acetylsalicylic acid
- anal
- diseases
- external
- hemorrhoid
- Prior art date
Links
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- 208000028990 Skin injury Diseases 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- 235000005764 Theobroma cacao ssp. cacao Nutrition 0.000 description 1
- 235000005767 Theobroma cacao ssp. sphaerocarpum Nutrition 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
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- 239000008272 agar Substances 0.000 description 1
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- BWZOPYPOZJBVLQ-UHFFFAOYSA-K aluminium glycinate Chemical compound O[Al+]O.NCC([O-])=O BWZOPYPOZJBVLQ-UHFFFAOYSA-K 0.000 description 1
- DIZPMCHEQGEION-UHFFFAOYSA-H aluminium sulfate (anhydrous) Chemical compound [Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O DIZPMCHEQGEION-UHFFFAOYSA-H 0.000 description 1
- 229940103272 aluminum potassium sulfate Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000410 anti-febrile effect Effects 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000003356 anti-rheumatic effect Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- SDNYTAYICBFYFH-TUFLPTIASA-N antipain Chemical compound NC(N)=NCCC[C@@H](C=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 SDNYTAYICBFYFH-TUFLPTIASA-N 0.000 description 1
- 239000003907 antipyretic analgesic agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- 235000001046 cacaotero Nutrition 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 229940046978 chlorpheniramine maleate Drugs 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 description 1
- JAUGGEIKQIHSMF-UHFFFAOYSA-N dialuminum;dimagnesium;dioxido(oxo)silane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[Mg+2].[Mg+2].[Al+3].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O.[O-][Si]([O-])=O JAUGGEIKQIHSMF-UHFFFAOYSA-N 0.000 description 1
- 229940015826 dihydroxyaluminum aminoacetate Drugs 0.000 description 1
- 229940031569 diisopropyl sebacate Drugs 0.000 description 1
- XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002878 effect on pruritus Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 229940116364 hard fat Drugs 0.000 description 1
- SFFVATKALSIZGN-UHFFFAOYSA-N hexadecan-7-ol Chemical compound CCCCCCCCCC(O)CCCCCC SFFVATKALSIZGN-UHFFFAOYSA-N 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229940100463 hexyl laurate Drugs 0.000 description 1
- 229960001067 hydrocortisone acetate Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229960004760 naphazoline hydrochloride Drugs 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 239000003883 ointment base Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
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- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229920000346 polystyrene-polyisoprene block-polystyrene Polymers 0.000 description 1
- 229920006264 polyurethane film Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- QEVHRUUCFGRFIF-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C(C5=CC=C(OC)C=C5N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 QEVHRUUCFGRFIF-MDEJGZGSSA-N 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
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- 229960005078 sorbitan sesquioleate Drugs 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
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- 229940021790 tetrahydrozoline hydrochloride Drugs 0.000 description 1
- BJORNXNYWNIWEY-UHFFFAOYSA-N tetrahydrozoline hydrochloride Chemical compound Cl.N1CCN=C1C1C2=CC=CC=C2CCC1 BJORNXNYWNIWEY-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
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- 239000001993 wax Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003044384A JP4791682B2 (ja) | 2003-02-21 | 2003-02-21 | 痔疾患用治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200506286B true ZA200506286B (en) | 2006-05-31 |
Family
ID=32905450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200506286A ZA200506286B (en) | 2003-02-21 | 2005-08-05 | Therapeutic agent for hemorrhoidal disease |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8183232B2 (ja) |
| EP (1) | EP1609472A4 (ja) |
| JP (1) | JP4791682B2 (ja) |
| KR (1) | KR101167317B1 (ja) |
| CN (1) | CN100594909C (ja) |
| AU (1) | AU2004212813B2 (ja) |
| CA (1) | CA2515259C (ja) |
| IL (1) | IL170151A (ja) |
| MX (1) | MXPA05008883A (ja) |
| NO (1) | NO20054320L (ja) |
| NZ (1) | NZ541931A (ja) |
| TW (1) | TWI315984B (ja) |
| WO (1) | WO2004073718A1 (ja) |
| ZA (1) | ZA200506286B (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100178255A1 (en) * | 2009-01-15 | 2010-07-15 | Madhavi Sekharam Kotha | Composition and method to treat otitis media and ventilator- associated pneumonia |
| KR101067443B1 (ko) | 2009-06-23 | 2011-09-27 | 여오영 | 하이드록시클로로퀸을 함유하는 치핵 치료를 위한 국소투여용 주사제 조성물 |
| WO2013070236A1 (en) * | 2011-11-11 | 2013-05-16 | Ventrus Biosciences, Inc. | Methods and compositions for treating hemorrhoids while providing local anesthetic and anti-inflammatory effects |
| JP6992057B2 (ja) | 2016-06-10 | 2022-01-13 | クラリティ コスメティックス インコーポレイテッド | 非面皰形成性の毛髪および頭皮ケア製剤ならびにその使用方法 |
| EP3834831A1 (en) | 2019-12-12 | 2021-06-16 | Hendrik de Keulenaer | Treatment of hemorrhoids with anticoagulant drugs |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3740420A (en) * | 1967-11-28 | 1973-06-19 | Crown Zellerbach Corp | Pharmaceutical compositions with dimethyl sulfoxide |
| US4126681A (en) * | 1975-12-08 | 1978-11-21 | The Procter & Gamble Company | Topical composition containing acetyl salicylic acid |
| US4383986A (en) * | 1981-08-17 | 1983-05-17 | Ortho Pharmaceutical Corporation | Hemorrhoidal compositions |
| US4613498A (en) * | 1984-10-24 | 1986-09-23 | Frank Crosby | Hemorrhoid medication |
| JPS635018A (ja) * | 1986-06-26 | 1988-01-11 | Kao Corp | 坐剤 |
| AU1778088A (en) | 1987-03-17 | 1989-12-21 | Mahmood Ali Dr. Khan | Use of analgesic anti-inflammatory drugs in treating haemorrhoidal bleeding |
| JPH08245369A (ja) * | 1995-03-08 | 1996-09-24 | Tendou Seiyaku Kk | 粘膜保護剤 |
| US5932230A (en) * | 1997-05-20 | 1999-08-03 | Degrate; Frenchell | Topical analgesic formulation containing fruits, oils and aspirin |
| JP4729149B2 (ja) * | 1997-06-25 | 2011-07-20 | 帝國製薬株式会社 | 安定なアスピリン軟膏製剤 |
| JPH1112177A (ja) * | 1997-06-25 | 1999-01-19 | Teikoku Seiyaku Co Ltd | 安定なアスピリン含有外用製剤 |
| JP4449213B2 (ja) * | 1997-10-08 | 2010-04-14 | 大正製薬株式会社 | 坐剤用組成物 |
| HU228233B1 (en) * | 1999-12-28 | 2013-02-28 | Teikoku Seiyaku Co | Antipruritic agents for external use |
| JP2001187739A (ja) | 1999-12-28 | 2001-07-10 | Teikoku Seiyaku Co Ltd | アレルギー性皮膚疾患治療用外用剤 |
| US7238680B2 (en) * | 2001-06-01 | 2007-07-03 | Rosen Steven E | Topical compositions for veterinary uses |
| CN1205951C (zh) * | 2002-06-10 | 2005-06-15 | 王兴泉 | 一种治疗腋臭和癣类及肛门外痔的药物组合物 |
| US20040062778A1 (en) * | 2002-09-26 | 2004-04-01 | Adi Shefer | Surface dissolution and/or bulk erosion controlled release compositions and devices |
-
2003
- 2003-02-21 JP JP2003044384A patent/JP4791682B2/ja not_active Expired - Fee Related
-
2004
- 2004-02-17 MX MXPA05008883A patent/MXPA05008883A/es active IP Right Grant
- 2004-02-17 EP EP04711719A patent/EP1609472A4/en not_active Ceased
- 2004-02-17 WO PCT/JP2004/001701 patent/WO2004073718A1/ja active Application Filing
- 2004-02-17 AU AU2004212813A patent/AU2004212813B2/en not_active Ceased
- 2004-02-17 US US10/545,910 patent/US8183232B2/en not_active Expired - Fee Related
- 2004-02-17 CA CA2515259A patent/CA2515259C/en not_active Expired - Fee Related
- 2004-02-17 NZ NZ541931A patent/NZ541931A/en not_active IP Right Cessation
- 2004-02-17 CN CN200480004668A patent/CN100594909C/zh not_active Expired - Fee Related
- 2004-02-17 TW TW093103794A patent/TWI315984B/zh not_active IP Right Cessation
- 2004-02-17 KR KR1020057015363A patent/KR101167317B1/ko active IP Right Grant
-
2005
- 2005-08-05 ZA ZA200506286A patent/ZA200506286B/en unknown
- 2005-08-08 IL IL170151A patent/IL170151A/en active IP Right Grant
- 2005-09-20 NO NO20054320A patent/NO20054320L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004073718A1 (ja) | 2004-09-02 |
| MXPA05008883A (es) | 2005-10-05 |
| KR20050102663A (ko) | 2005-10-26 |
| NO20054320D0 (no) | 2005-09-20 |
| US8183232B2 (en) | 2012-05-22 |
| CN1750831A (zh) | 2006-03-22 |
| CA2515259C (en) | 2012-09-18 |
| CA2515259A1 (en) | 2004-09-02 |
| NO20054320L (no) | 2005-11-18 |
| JP2004262775A (ja) | 2004-09-24 |
| EP1609472A4 (en) | 2007-10-24 |
| TW200509945A (en) | 2005-03-16 |
| CN100594909C (zh) | 2010-03-24 |
| KR101167317B1 (ko) | 2012-07-19 |
| TWI315984B (en) | 2009-10-21 |
| EP1609472A1 (en) | 2005-12-28 |
| AU2004212813A1 (en) | 2004-09-02 |
| NZ541931A (en) | 2010-10-29 |
| AU2004212813B2 (en) | 2009-02-26 |
| JP4791682B2 (ja) | 2011-10-12 |
| US20060159711A1 (en) | 2006-07-20 |
| IL170151A (en) | 2015-04-30 |
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