ZA200505077B - Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives - Google Patents
Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives Download PDFInfo
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- ZA200505077B ZA200505077B ZA200505077A ZA200505077A ZA200505077B ZA 200505077 B ZA200505077 B ZA 200505077B ZA 200505077 A ZA200505077 A ZA 200505077A ZA 200505077 A ZA200505077 A ZA 200505077A ZA 200505077 B ZA200505077 B ZA 200505077B
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- South Africa
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- compound
- atropisomer
- composition
- chloro
- trifluoromethyl
- Prior art date
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Classifications
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43616002P | 2002-12-23 | 2002-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200505077B true ZA200505077B (en) | 2006-09-27 |
Family
ID=32682352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200505077A ZA200505077B (en) | 2002-12-23 | 2005-06-22 | Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6939968B2 (de) |
| EP (1) | EP1575589B1 (de) |
| JP (1) | JP2006512378A (de) |
| KR (1) | KR20050102081A (de) |
| CN (1) | CN1750821A (de) |
| AT (1) | ATE472328T1 (de) |
| AU (1) | AU2003300425A1 (de) |
| BR (1) | BR0317679A (de) |
| CZ (1) | CZ2005407A3 (de) |
| DE (1) | DE60333226D1 (de) |
| IL (1) | IL169294A (de) |
| MX (1) | MXPA05006814A (de) |
| NO (1) | NO20053078L (de) |
| NZ (1) | NZ541237A (de) |
| PL (1) | PL377492A1 (de) |
| RU (1) | RU2352563C2 (de) |
| TR (1) | TR200502440T2 (de) |
| WO (1) | WO2004058260A1 (de) |
| ZA (1) | ZA200505077B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140048337A (ko) * | 2007-04-09 | 2014-04-23 | 다이이찌 산쿄 가부시키가이샤 | 피롤 유도체의 아트로프 이성체 |
| US8680116B2 (en) | 2009-07-22 | 2014-03-25 | Merck Sharp & Dohme Corp. | Quinolinone PDE2 inhibitors |
| BR112015025729B1 (pt) * | 2013-04-10 | 2023-04-25 | Daiichi Sankyo Company, Limited | Métodos para resolver e para produzir um composto |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW504504B (en) | 1996-11-26 | 2002-10-01 | Bristol Myers Squibb Co | 4-aryl-3-hydroxyquinolin-2-one derivatives as ion channel modulators |
| SK113299A3 (en) * | 1997-02-28 | 2001-05-10 | Pfizer Prod Inc | Atropisomers of 3-aryl-4(3h)-quinazolinones and their use as ampa-receptor antagonists |
| AU755202B2 (en) * | 1998-12-04 | 2002-12-05 | Bristol-Myers Squibb Company | 3-substituted-4-arylquinolin-2-one derivatives as potassium channel modulators |
| TW562799B (en) * | 1999-12-01 | 2003-11-21 | Bristol Myers Squibb Co | Preparation of 3-substituted-4-arylquinolin-2-one derivatives |
| EP1345603A4 (de) * | 2000-12-20 | 2004-09-08 | Merck & Co Inc | (halo-benzo-carbonyl)heterocyclo-kondensierte phenyl-p38-kinase hemmende mittel |
-
2003
- 2003-12-17 US US10/739,449 patent/US6939968B2/en not_active Expired - Fee Related
- 2003-12-18 MX MXPA05006814A patent/MXPA05006814A/es active IP Right Grant
- 2003-12-18 CZ CZ2005407A patent/CZ2005407A3/cs unknown
- 2003-12-18 JP JP2004562595A patent/JP2006512378A/ja active Pending
- 2003-12-18 WO PCT/US2003/041548 patent/WO2004058260A1/en active Application Filing
- 2003-12-18 AT AT03814399T patent/ATE472328T1/de not_active IP Right Cessation
- 2003-12-18 EP EP03814399A patent/EP1575589B1/de not_active Expired - Lifetime
- 2003-12-18 DE DE60333226T patent/DE60333226D1/de not_active Expired - Lifetime
- 2003-12-18 PL PL377492A patent/PL377492A1/pl not_active Application Discontinuation
- 2003-12-18 BR BR0317679-7A patent/BR0317679A/pt not_active IP Right Cessation
- 2003-12-18 NZ NZ541237A patent/NZ541237A/en unknown
- 2003-12-18 RU RU2005123046/04A patent/RU2352563C2/ru not_active IP Right Cessation
- 2003-12-18 KR KR1020057011916A patent/KR20050102081A/ko not_active Application Discontinuation
- 2003-12-18 CN CNA2003801098331A patent/CN1750821A/zh active Pending
- 2003-12-18 TR TR2005/02440T patent/TR200502440T2/xx unknown
- 2003-12-18 AU AU2003300425A patent/AU2003300425A1/en not_active Abandoned
-
2005
- 2005-06-20 IL IL169294A patent/IL169294A/en not_active IP Right Cessation
- 2005-06-22 ZA ZA200505077A patent/ZA200505077B/en unknown
- 2005-06-23 NO NO20053078A patent/NO20053078L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6939968B2 (en) | 2005-09-06 |
| AU2003300425A1 (en) | 2004-07-22 |
| CN1750821A (zh) | 2006-03-22 |
| IL169294A (en) | 2010-11-30 |
| MXPA05006814A (es) | 2005-09-08 |
| NO20053078L (no) | 2005-08-29 |
| NO20053078D0 (no) | 2005-06-23 |
| WO2004058260A1 (en) | 2004-07-15 |
| KR20050102081A (ko) | 2005-10-25 |
| DE60333226D1 (de) | 2010-08-12 |
| JP2006512378A (ja) | 2006-04-13 |
| EP1575589A4 (de) | 2008-05-21 |
| ATE472328T1 (de) | 2010-07-15 |
| RU2005123046A (ru) | 2006-01-20 |
| RU2352563C2 (ru) | 2009-04-20 |
| US20040147749A1 (en) | 2004-07-29 |
| CZ2005407A3 (cs) | 2005-10-12 |
| TR200502440T2 (tr) | 2005-10-21 |
| BR0317679A (pt) | 2005-11-29 |
| EP1575589B1 (de) | 2010-06-30 |
| NZ541237A (en) | 2008-09-26 |
| PL377492A1 (pl) | 2006-02-06 |
| EP1575589A1 (de) | 2005-09-21 |
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