ZA200502572B - Multimeric protein engineering - Google Patents

Multimeric protein engineering Download PDF

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Publication number
ZA200502572B
ZA200502572B ZA200502572A ZA200502572A ZA200502572B ZA 200502572 B ZA200502572 B ZA 200502572B ZA 200502572 A ZA200502572 A ZA 200502572A ZA 200502572 A ZA200502572 A ZA 200502572A ZA 200502572 B ZA200502572 B ZA 200502572B
Authority
ZA
South Africa
Prior art keywords
peptide
antibody
heavy chain
light chain
sequence
Prior art date
Application number
ZA200502572A
Other languages
English (en)
Inventor
Stephen J Reinl
Edwards Patricia
Original Assignee
Large Scale Biology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Large Scale Biology Corp filed Critical Large Scale Biology Corp
Publication of ZA200502572B publication Critical patent/ZA200502572B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/13Immunoglobulins specific features characterized by their source of isolation or production isolated from plants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
ZA200502572A 2002-10-03 2005-03-30 Multimeric protein engineering ZA200502572B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41594002P 2002-10-03 2002-10-03

Publications (1)

Publication Number Publication Date
ZA200502572B true ZA200502572B (en) 2006-11-29

Family

ID=32069923

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200502572A ZA200502572B (en) 2002-10-03 2005-03-30 Multimeric protein engineering

Country Status (7)

Country Link
US (2) US20040110930A1 (ja)
EP (1) EP1556403A4 (ja)
JP (1) JP2006506056A (ja)
AU (1) AU2003282667A1 (ja)
CA (1) CA2499891A1 (ja)
WO (1) WO2004031362A2 (ja)
ZA (1) ZA200502572B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100447530B1 (ko) * 2001-08-14 2004-09-08 한국과학기술원 OmpF를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법
WO2006065273A2 (en) * 2004-05-24 2006-06-22 The Regents Of The University Of California New human parvovirus
CN100460508C (zh) * 2004-11-03 2009-02-11 马延高 人胰岛素基因在甲醇酵母中的分泌表达方法
US20110038854A1 (en) * 2006-03-30 2011-02-17 University Of Medicine And Dentistry Of New Jersey Strategy for homo- or hetero-dimerization of various proteins in solution and in cell
EP1997830A1 (en) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
RU2595409C2 (ru) * 2009-09-03 2016-08-27 Мерк Шарп И Доум Корп., Анти-gitr-антитела
KR102159109B1 (ko) * 2011-11-16 2020-09-23 베링거 인겔하임 인터내셔날 게엠베하 항 il-36r 항체
EA031715B1 (ru) 2011-12-19 2019-02-28 Дзе Рокфеллер Юниверсити ПРОТИВОВОСПАЛИТЕЛЬНЫЙ НЕСИАЛИРОВАННЫЙ ПОЛИПЕПТИД МОДИФИЦИРОВАННОГО Fc-УЧАСТКА hIgG1, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ
EP2906599B1 (en) * 2012-10-12 2019-07-17 Agency For Science, Technology And Research Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics
WO2014124457A1 (en) * 2013-02-11 2014-08-14 University Of Louisville Research Foundation, Inc. Methods for producing antibodies
US11155615B2 (en) 2015-05-18 2021-10-26 Eureka Therapeutics, Inc. Anti-ROR1 antibodies
DK3344287T3 (da) * 2015-09-04 2021-07-19 Health Research Inc Anti-survivin-antistoffer til cancerterapi
EP3455630A4 (en) 2016-05-13 2020-01-08 MBL International Corp. PEPTIDE EXCHANGE SYSTEM AND METHOD
BR112020004764A2 (pt) 2017-09-11 2020-09-24 R.J. Reynolds Tobacco Company métodos e composições para aumentar a expressão de genes de interesse em uma planta por coexpressão com p21
CN113543772A (zh) 2019-03-08 2021-10-22 勃林格殷格翰国际有限公司 抗il-36r抗体制剂

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5959177A (en) * 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US7005560B1 (en) * 1989-10-27 2006-02-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5202422A (en) * 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
US6046037A (en) * 1994-12-30 2000-04-04 Hiatt; Andrew C. Method for producing immunoglobulins containing protection proteins in plants and their use
CA2246242A1 (en) * 1996-02-08 1997-08-14 Institut Fur Pflanzengenetik Und Kulturpflanzenforschung Cassettes for the expression of storable proteins in plants
US6045774A (en) * 1997-01-10 2000-04-04 Epicyte Pharmaceutical Inc. J chain polypeptide targeting molecule linked to an imaging agent
US6251392B1 (en) * 1997-10-20 2001-06-26 Epicyte Pharmaceuticals, Inc. Epithelial cell targeting agent

Also Published As

Publication number Publication date
AU2003282667A1 (en) 2004-04-23
WO2004031362A2 (en) 2004-04-15
JP2006506056A (ja) 2006-02-23
WO2004031362A8 (en) 2004-06-10
EP1556403A2 (en) 2005-07-27
US20050207977A1 (en) 2005-09-22
US20040110930A1 (en) 2004-06-10
WO2004031362A3 (en) 2004-12-02
EP1556403A4 (en) 2006-06-28
CA2499891A1 (en) 2004-04-15

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