ZA200501274B - Estrogen replacement regimen - Google Patents

Estrogen replacement regimen Download PDF

Info

Publication number
ZA200501274B
ZA200501274B ZA200501274A ZA200501274A ZA200501274B ZA 200501274 B ZA200501274 B ZA 200501274B ZA 200501274 A ZA200501274 A ZA 200501274A ZA 200501274 A ZA200501274 A ZA 200501274A ZA 200501274 B ZA200501274 B ZA 200501274B
Authority
ZA
South Africa
Prior art keywords
unit doses
daily unit
dose estrogen
substance exhibiting
doses
Prior art date
Application number
ZA200501274A
Other languages
English (en)
Inventor
Robert Casper
Zeev Shoham
Gideon Kopernik
Original Assignee
Robert Casper
Gideon Kopernik
Zeev Shoham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Casper, Gideon Kopernik, Zeev Shoham filed Critical Robert Casper
Publication of ZA200501274B publication Critical patent/ZA200501274B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200501274A 2002-08-28 2005-02-11 Estrogen replacement regimen ZA200501274B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40633102P 2002-08-28 2002-08-28

Publications (1)

Publication Number Publication Date
ZA200501274B true ZA200501274B (en) 2006-08-30

Family

ID=31978284

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200501274A ZA200501274B (en) 2002-08-28 2005-02-11 Estrogen replacement regimen

Country Status (25)

Country Link
US (1) US8946198B2 (https=)
EP (1) EP1539184B1 (https=)
JP (1) JP2005538150A (https=)
KR (1) KR20050059092A (https=)
CN (1) CN1678324A (https=)
AT (1) ATE345804T1 (https=)
AU (1) AU2003264203A1 (https=)
BR (1) BR0313921A (https=)
CA (1) CA2495330A1 (https=)
CY (1) CY1106019T1 (https=)
DE (1) DE60309895T2 (https=)
DK (1) DK1539184T3 (https=)
ES (1) ES2277139T3 (https=)
HR (1) HRP20050291A2 (https=)
IL (1) IL166585A0 (https=)
MX (1) MXPA05002294A (https=)
NO (1) NO20051545L (https=)
NZ (1) NZ538342A (https=)
PL (1) PL374762A1 (https=)
PT (1) PT1539184E (https=)
RS (1) RS20050184A (https=)
RU (1) RU2340345C2 (https=)
UA (1) UA82851C2 (https=)
WO (1) WO2004019954A1 (https=)
ZA (1) ZA200501274B (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
DE102009007771B4 (de) 2009-02-05 2012-02-16 Bayer Schering Pharma Aktiengesellschaft Bukkales Applikationssystem, 17α-Estradiol enthaltend
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
MX2016011801A (es) * 2014-03-12 2017-07-14 Warner Chilcott Co Llc Crema de estradiol de dosis baja.
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
LT3310345T (lt) 2015-06-18 2021-06-25 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
CR20180042A (es) 2015-06-18 2018-05-03 Mithra Pharmaceuticals S A Unidad de dosificación orodispersable que contiene un componente estetrol.
DK3701944T3 (da) 2015-06-18 2022-03-14 Estetra Srl Oro-dispergerbar doseringsenhed indeholdende en estetrolkomponent
LT3310346T (lt) 2015-06-18 2021-06-10 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
AU2016284459B2 (en) 2015-06-22 2021-12-23 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
CN111989105B (zh) 2018-04-19 2024-07-19 埃斯特拉私人有限责任公司 化合物以及它们在缓解绝经相关症状中的用途
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
EP0303306B1 (en) * 1987-08-08 1993-03-10 Akzo N.V. Contraceptive implant
US4900734A (en) * 1987-08-27 1990-02-13 Maxson Wayne S Novel pharmaceutical composition containing estradiol and progesterone for oral administration
US5108995A (en) * 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
US5256421A (en) * 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
US5422119A (en) * 1987-09-24 1995-06-06 Jencap Research Ltd. Transdermal hormone replacement therapy
US5276022A (en) * 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
DE3888269T2 (de) * 1987-09-24 1994-07-07 Jencap Research Ltd Hormon-Zusammensetzung und -Anwendung.
US5382873A (en) * 1991-12-04 1995-01-17 U.S. Philips Corporation High-pressure discharge lamp with incandescing metal droplets
US5521166A (en) * 1994-12-19 1996-05-28 Ortho Pharmaceitical Corporation Antiprogestin cyclophasic hormonal regimen
DE19513662A1 (de) * 1995-04-08 1996-10-10 Schering Ag Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption
CN1188189C (zh) * 1995-06-07 2005-02-09 奥瑟-麦内尔制药公司 基质层含有17-脱乙酰基诺孕酯的经皮贴片及基质的用途
US6506390B2 (en) * 1996-06-25 2003-01-14 Akzo Nobel Progestogen-anti-progestogen regimens
CA2267743C (en) * 1999-03-30 2011-07-26 Robert F. Casper Low dose estrogen interrupted hormone replacement therapy
US6653298B2 (en) * 2000-01-14 2003-11-25 Sterix Limited Composition
DE10100911A1 (de) * 2001-01-11 2002-08-01 Schering Ag Verfahren zur Hormonersatztherapie und dessen Darreichungsform

Also Published As

Publication number Publication date
AU2003264203A1 (en) 2004-03-19
MXPA05002294A (es) 2005-09-12
JP2005538150A (ja) 2005-12-15
NZ538342A (en) 2007-08-31
RS20050184A (sr) 2007-11-15
DE60309895D1 (de) 2007-01-04
ATE345804T1 (de) 2006-12-15
US8946198B2 (en) 2015-02-03
HRP20050291A2 (en) 2005-10-31
WO2004019954A1 (en) 2004-03-11
EP1539184B1 (en) 2006-11-22
DE60309895T2 (de) 2007-10-18
UA82851C2 (en) 2008-05-26
PT1539184E (pt) 2007-02-28
RU2340345C2 (ru) 2008-12-10
US20060089337A1 (en) 2006-04-27
ES2277139T3 (es) 2007-07-01
NO20051545L (no) 2005-03-23
RU2005108977A (ru) 2005-10-10
IL166585A0 (en) 2006-01-15
DK1539184T3 (da) 2007-03-19
CN1678324A (zh) 2005-10-05
CY1106019T1 (el) 2011-04-06
BR0313921A (pt) 2005-07-19
EP1539184A1 (en) 2005-06-15
CA2495330A1 (en) 2004-03-11
KR20050059092A (ko) 2005-06-17
PL374762A1 (en) 2005-10-31

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