DE60309895D1 - Estrogenersatztherapie - Google Patents

Estrogenersatztherapie

Info

Publication number
DE60309895D1
DE60309895D1 DE60309895T DE60309895T DE60309895D1 DE 60309895 D1 DE60309895 D1 DE 60309895D1 DE 60309895 T DE60309895 T DE 60309895T DE 60309895 T DE60309895 T DE 60309895T DE 60309895 D1 DE60309895 D1 DE 60309895D1
Authority
DE
Germany
Prior art keywords
replacement therapy
estrogen replacement
estrogen
dose estradiol
alternating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60309895T
Other languages
English (en)
Other versions
DE60309895T2 (de
Inventor
Robert Casper
Gideon Kopernik
Zeev Shoham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60309895D1 publication Critical patent/DE60309895D1/de
Publication of DE60309895T2 publication Critical patent/DE60309895T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60309895T 2002-08-28 2003-08-28 Estrogenersatztherapie Expired - Lifetime DE60309895T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40633102P 2002-08-28 2002-08-28
US406331P 2002-08-28
PCT/CA2003/001325 WO2004019954A1 (en) 2002-08-28 2003-08-28 Estrogen replacement regimen

Publications (2)

Publication Number Publication Date
DE60309895D1 true DE60309895D1 (de) 2007-01-04
DE60309895T2 DE60309895T2 (de) 2007-10-18

Family

ID=31978284

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60309895T Expired - Lifetime DE60309895T2 (de) 2002-08-28 2003-08-28 Estrogenersatztherapie

Country Status (25)

Country Link
US (1) US8946198B2 (de)
EP (1) EP1539184B1 (de)
JP (1) JP2005538150A (de)
KR (1) KR20050059092A (de)
CN (1) CN1678324A (de)
AT (1) ATE345804T1 (de)
AU (1) AU2003264203A1 (de)
BR (1) BR0313921A (de)
CA (1) CA2495330A1 (de)
CY (1) CY1106019T1 (de)
DE (1) DE60309895T2 (de)
DK (1) DK1539184T3 (de)
ES (1) ES2277139T3 (de)
HR (1) HRP20050291A2 (de)
IL (1) IL166585A0 (de)
MX (1) MXPA05002294A (de)
NO (1) NO20051545L (de)
NZ (1) NZ538342A (de)
PL (1) PL374762A1 (de)
PT (1) PT1539184E (de)
RS (1) RS20050184A (de)
RU (1) RU2340345C2 (de)
UA (1) UA82851C2 (de)
WO (1) WO2004019954A1 (de)
ZA (1) ZA200501274B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
DE102009007771B4 (de) 2009-02-05 2012-02-16 Bayer Schering Pharma Aktiengesellschaft Bukkales Applikationssystem, 17α-Estradiol enthaltend
EP2383279A1 (de) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Herstellungsverfahren für Esterol
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
EP3116474A1 (de) * 2014-03-12 2017-01-18 Warner Chilcott Company, LLC Niedrigdosierte estradiolcreme
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
UA123098C2 (uk) 2015-06-18 2021-02-17 Естетра Спрл Диспергована у порожнині рота одиниця дозування, що містить естетрольний компонент
EA035687B1 (ru) 2015-06-18 2020-07-27 Эстетра Спрл Диспергируемая в полости рта единица дозирования, содержащая эстетрольный компонент
DK3310345T3 (da) 2015-06-18 2021-05-25 Estetra Sprl Orodispersibel tablet indeholdende estetrol
EP3310346B1 (de) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablette enthaltend estetrol
JP2018522854A (ja) 2015-06-22 2018-08-16 リポカイン インコーポレーテッド １７−ヒドロキシプロゲステロンエステル含有経口組成物及び関連方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
DE19975054I2 (de) 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
US4900734A (en) * 1987-08-27 1990-02-13 Maxson Wayne S Novel pharmaceutical composition containing estradiol and progesterone for oral administration
US5276022A (en) 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
US5108995A (en) 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
NO301689B1 (no) * 1987-09-24 1997-12-01 Jencap Research Ltd Kontraseptivt preparat i form av en forpakning
US5256421A (en) 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
US5422119A (en) 1987-09-24 1995-06-06 Jencap Research Ltd. Transdermal hormone replacement therapy
US5382873A (en) 1991-12-04 1995-01-17 U.S. Philips Corporation High-pressure discharge lamp with incandescing metal droplets
US5521166A (en) * 1994-12-19 1996-05-28 Ortho Pharmaceitical Corporation Antiprogestin cyclophasic hormonal regimen
US6506390B2 (en) * 1996-06-25 2003-01-14 Akzo Nobel Progestogen-anti-progestogen regimens
US6653298B2 (en) * 2000-01-14 2003-11-25 Sterix Limited Composition
DE10100911A1 (de) * 2001-01-11 2002-08-01 Schering Ag Verfahren zur Hormonersatztherapie und dessen Darreichungsform

Also Published As

Publication number Publication date
AU2003264203A1 (en) 2004-03-19
RU2340345C2 (ru) 2008-12-10
NO20051545L (no) 2005-03-23
HRP20050291A2 (en) 2005-10-31
PT1539184E (pt) 2007-02-28
NZ538342A (en) 2007-08-31
DE60309895T2 (de) 2007-10-18
RU2005108977A (ru) 2005-10-10
DK1539184T3 (da) 2007-03-19
ATE345804T1 (de) 2006-12-15
UA82851C2 (en) 2008-05-26
ES2277139T3 (es) 2007-07-01
ZA200501274B (en) 2006-08-30
WO2004019954A1 (en) 2004-03-11
KR20050059092A (ko) 2005-06-17
CA2495330A1 (en) 2004-03-11
MXPA05002294A (es) 2005-09-12
EP1539184A1 (de) 2005-06-15
EP1539184B1 (de) 2006-11-22
PL374762A1 (en) 2005-10-31
CN1678324A (zh) 2005-10-05
RS20050184A (en) 2007-11-15
JP2005538150A (ja) 2005-12-15
BR0313921A (pt) 2005-07-19
CY1106019T1 (el) 2011-04-06
IL166585A0 (en) 2006-01-15
US20060089337A1 (en) 2006-04-27
US8946198B2 (en) 2015-02-03

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Legal Events

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