AU2003264203A1 - Estrogen replacement regimen - Google Patents
Estrogen replacement regimen Download PDFInfo
- Publication number
- AU2003264203A1 AU2003264203A1 AU2003264203A AU2003264203A AU2003264203A1 AU 2003264203 A1 AU2003264203 A1 AU 2003264203A1 AU 2003264203 A AU2003264203 A AU 2003264203A AU 2003264203 A AU2003264203 A AU 2003264203A AU 2003264203 A1 AU2003264203 A1 AU 2003264203A1
- Authority
- AU
- Australia
- Prior art keywords
- unit doses
- daily unit
- dose estrogen
- substance exhibiting
- doses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229940011871 estrogen Drugs 0.000 title claims abstract description 430
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- 238000000034 method Methods 0.000 claims abstract description 45
- 230000001747 exhibiting effect Effects 0.000 claims description 219
- 239000000126 substance Substances 0.000 claims description 207
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- 230000001076 estrogenic effect Effects 0.000 claims description 125
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Endocrinology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| DE102009007771B4 (de) | 2009-02-05 | 2012-02-16 | Bayer Schering Pharma Aktiengesellschaft | Bukkales Applikationssystem, 17α-Estradiol enthaltend |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| CA2942345C (en) * | 2014-03-12 | 2020-12-01 | Warner Chilcott Company, Llc | Low-dose estradiol cream |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| MD3310333T2 (ro) | 2015-06-18 | 2020-06-30 | Estetra Sprl | Unitate de dozare orodispersabilă care conține un component estetrol |
| RS61777B1 (sr) | 2015-06-18 | 2021-06-30 | Estetra Sprl | Oralno-disperzibilna tableta koja sadrži estetrol |
| HUE054589T2 (hu) | 2015-06-18 | 2021-09-28 | Estetra Sprl | Szájban diszpergálódó esztetrol tartalmú tabletta |
| CN116077454A (zh) | 2015-06-18 | 2023-05-09 | 埃斯特拉有限责任公司 | 含雌四醇组分的口腔分散剂量单位 |
| CN107847506A (zh) | 2015-06-22 | 2018-03-27 | 来普卡公司 | 含17‑羟基孕酮酯的口服组合物和相关方法 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
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| US4826831A (en) * | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
| ES2054784T3 (es) | 1987-08-08 | 1994-08-16 | Akzo Nv | Un metodo para la fabricacion de un implante. |
| US4900734A (en) * | 1987-08-27 | 1990-02-13 | Maxson Wayne S | Novel pharmaceutical composition containing estradiol and progesterone for oral administration |
| AU630334B2 (en) * | 1987-09-24 | 1992-10-29 | Jencap Research Ltd. | Hormone preparations for hormone replacement therapy and contraceptive method |
| US5256421A (en) | 1987-09-24 | 1993-10-26 | Jencap Research Ltd. | Hormone preparation and method |
| US5422119A (en) | 1987-09-24 | 1995-06-06 | Jencap Research Ltd. | Transdermal hormone replacement therapy |
| US5276022A (en) | 1987-09-24 | 1994-01-04 | Jencap Research Ltd. | Hormone preparation and method |
| US5108995A (en) | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
| US5382873A (en) | 1991-12-04 | 1995-01-17 | U.S. Philips Corporation | High-pressure discharge lamp with incandescing metal droplets |
| US5521166A (en) * | 1994-12-19 | 1996-05-28 | Ortho Pharmaceitical Corporation | Antiprogestin cyclophasic hormonal regimen |
| DE19513662A1 (de) * | 1995-04-08 | 1996-10-10 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
| CA2222133C (en) * | 1995-06-07 | 2002-12-24 | Cygnus, Inc. | Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen |
| US6506390B2 (en) * | 1996-06-25 | 2003-01-14 | Akzo Nobel | Progestogen-anti-progestogen regimens |
| CA2267743C (en) * | 1999-03-30 | 2011-07-26 | Robert F. Casper | Low dose estrogen interrupted hormone replacement therapy |
| US6653298B2 (en) * | 2000-01-14 | 2003-11-25 | Sterix Limited | Composition |
| DE10100911A1 (de) * | 2001-01-11 | 2002-08-01 | Schering Ag | Verfahren zur Hormonersatztherapie und dessen Darreichungsform |
-
2003
- 2003-08-28 CN CNA038205157A patent/CN1678324A/zh active Pending
- 2003-08-28 RS YUP-2005/0184A patent/RS20050184A/sr unknown
- 2003-08-28 PT PT03790602T patent/PT1539184E/pt unknown
- 2003-08-28 DE DE60309895T patent/DE60309895T2/de not_active Expired - Lifetime
- 2003-08-28 HR HR20050291A patent/HRP20050291A2/xx not_active Application Discontinuation
- 2003-08-28 EP EP03790602A patent/EP1539184B1/en not_active Expired - Lifetime
- 2003-08-28 ES ES03790602T patent/ES2277139T3/es not_active Expired - Lifetime
- 2003-08-28 AU AU2003264203A patent/AU2003264203A1/en not_active Abandoned
- 2003-08-28 UA UAA200502488A patent/UA82851C2/uk unknown
- 2003-08-28 NZ NZ538342A patent/NZ538342A/en unknown
- 2003-08-28 DK DK03790602T patent/DK1539184T3/da active
- 2003-08-28 BR BR0313921-2A patent/BR0313921A/pt not_active IP Right Cessation
- 2003-08-28 US US10/526,064 patent/US8946198B2/en active Active
- 2003-08-28 PL PL03374762A patent/PL374762A1/xx not_active Application Discontinuation
- 2003-08-28 IL IL16658503A patent/IL166585A0/xx unknown
- 2003-08-28 WO PCT/CA2003/001325 patent/WO2004019954A1/en not_active Ceased
- 2003-08-28 AT AT03790602T patent/ATE345804T1/de not_active IP Right Cessation
- 2003-08-28 RU RU2005108977/15A patent/RU2340345C2/ru not_active IP Right Cessation
- 2003-08-28 CA CA002495330A patent/CA2495330A1/en not_active Abandoned
- 2003-08-28 KR KR1020057003209A patent/KR20050059092A/ko not_active Withdrawn
- 2003-08-28 JP JP2004531341A patent/JP2005538150A/ja active Pending
- 2003-08-28 MX MXPA05002294A patent/MXPA05002294A/es active IP Right Grant
-
2005
- 2005-02-11 ZA ZA200501274A patent/ZA200501274B/en unknown
- 2005-03-23 NO NO20051545A patent/NO20051545L/no not_active Application Discontinuation
-
2007
- 2007-02-14 CY CY20071100200T patent/CY1106019T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1539184A1 (en) | 2005-06-15 |
| RS20050184A (sr) | 2007-11-15 |
| CY1106019T1 (el) | 2011-04-06 |
| US20060089337A1 (en) | 2006-04-27 |
| DE60309895T2 (de) | 2007-10-18 |
| RU2005108977A (ru) | 2005-10-10 |
| BR0313921A (pt) | 2005-07-19 |
| UA82851C2 (en) | 2008-05-26 |
| HRP20050291A2 (en) | 2005-10-31 |
| MXPA05002294A (es) | 2005-09-12 |
| CA2495330A1 (en) | 2004-03-11 |
| NO20051545L (no) | 2005-03-23 |
| WO2004019954A1 (en) | 2004-03-11 |
| ES2277139T3 (es) | 2007-07-01 |
| DK1539184T3 (da) | 2007-03-19 |
| RU2340345C2 (ru) | 2008-12-10 |
| CN1678324A (zh) | 2005-10-05 |
| JP2005538150A (ja) | 2005-12-15 |
| PT1539184E (pt) | 2007-02-28 |
| DE60309895D1 (de) | 2007-01-04 |
| ATE345804T1 (de) | 2006-12-15 |
| EP1539184B1 (en) | 2006-11-22 |
| KR20050059092A (ko) | 2005-06-17 |
| NZ538342A (en) | 2007-08-31 |
| US8946198B2 (en) | 2015-02-03 |
| ZA200501274B (en) | 2006-08-30 |
| PL374762A1 (en) | 2005-10-31 |
| IL166585A0 (en) | 2006-01-15 |
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Legal Events
| Date | Code | Title | Description |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |