ZA200500478B - Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors - Google Patents

Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors

Info

Publication number
ZA200500478B
ZA200500478B ZA200500478A ZA200500478A ZA200500478B ZA 200500478 B ZA200500478 B ZA 200500478B ZA 200500478 A ZA200500478 A ZA 200500478A ZA 200500478 A ZA200500478 A ZA 200500478A ZA 200500478 B ZA200500478 B ZA 200500478B
Authority
ZA
South Africa
Prior art keywords
ligands
receptors
acyloxypyrrolidine
derivatives
acyloxypyrrolidine derivatives
Prior art date
Application number
ZA200500478A
Other languages
English (en)
Inventor
Alain Aulombard
Georges Garcia
Antoine Pradines
Claudine Serradeil-Le Gal
Jean Wagnon
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ZA200500478B publication Critical patent/ZA200500478B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200500478A 2002-07-19 2005-01-18 Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors ZA200500478B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0209242A FR2842527B1 (fr) 2002-07-19 2002-07-19 Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA200500478B true ZA200500478B (en) 2006-07-26

Family

ID=29797610

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500478A ZA200500478B (en) 2002-07-19 2005-01-18 Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors

Country Status (28)

Country Link
US (1) US7202267B2 (ru)
EP (1) EP1525198B1 (ru)
JP (1) JP4264414B2 (ru)
CN (1) CN100425608C (ru)
AR (1) AR040571A1 (ru)
AT (1) ATE312092T1 (ru)
AU (1) AU2003271815B8 (ru)
BR (1) BR0312800A (ru)
CA (1) CA2492224A1 (ru)
DE (1) DE60302670T2 (ru)
DK (1) DK1525198T3 (ru)
EA (1) EA008444B1 (ru)
ES (1) ES2254962T3 (ru)
FR (1) FR2842527B1 (ru)
HK (1) HK1074444A1 (ru)
HR (1) HRP20041231A2 (ru)
IL (1) IL165942A (ru)
IS (1) IS2487B (ru)
ME (1) MEP12408A (ru)
MX (1) MXPA05000822A (ru)
NO (1) NO20050292L (ru)
NZ (1) NZ537615A (ru)
PL (1) PL375309A1 (ru)
RS (1) RS20050018A (ru)
TW (1) TWI274751B (ru)
UA (1) UA78805C2 (ru)
WO (1) WO2004009585A2 (ru)
ZA (1) ZA200500478B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7528124B2 (en) 2003-08-28 2009-05-05 Taisho Pharmaceutical Co., Ltd. 1,3-dihydro-2H-indol-2-one derivative
TW200643015A (en) 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
DE102005015957A1 (de) * 2005-03-31 2006-10-05 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
US8350043B2 (en) 2005-06-07 2013-01-08 Pharmacopeia, Inc. Azinone and diazinone V3 inhibitors for depression and stress disorders
EP2069315B1 (en) 2006-09-11 2011-09-07 N.V. Organon Quinazolinone and isoquinolinone acetamide derivatives
CN103864658B (zh) * 2014-03-06 2016-06-15 南京工业大学 氮杂环丁酮衍生物及其制备方法与应用
CN104447489B (zh) * 2014-12-29 2017-01-11 南京工业大学 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804114B1 (fr) * 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
MEP12408A (en) 2010-06-10
DE60302670D1 (de) 2006-01-12
NZ537615A (en) 2006-11-30
AR040571A1 (es) 2005-04-13
JP4264414B2 (ja) 2009-05-20
IL165942A (en) 2010-04-15
NO20050292L (no) 2005-04-19
EA008444B1 (ru) 2007-06-29
IS2487B (is) 2008-12-15
ES2254962T3 (es) 2006-06-16
UA78805C2 (en) 2007-04-25
IL165942A0 (en) 2006-01-15
IS7641A (is) 2005-01-12
CN100425608C (zh) 2008-10-15
ATE312092T1 (de) 2005-12-15
FR2842527B1 (fr) 2005-01-28
DE60302670T2 (de) 2006-09-07
DK1525198T3 (da) 2006-04-18
US20050192335A1 (en) 2005-09-01
TWI274751B (en) 2007-03-01
CN1681806A (zh) 2005-10-12
HRP20041231A2 (en) 2005-02-28
US7202267B2 (en) 2007-04-10
AU2003271815A1 (en) 2004-02-09
WO2004009585A2 (fr) 2004-01-29
HK1074444A1 (en) 2005-11-11
CA2492224A1 (en) 2004-01-29
BR0312800A (pt) 2005-04-19
JP2005537271A (ja) 2005-12-08
WO2004009585A3 (fr) 2004-05-06
AU2003271815B8 (en) 2009-04-30
EP1525198A2 (fr) 2005-04-27
FR2842527A1 (fr) 2004-01-23
MXPA05000822A (es) 2005-08-29
EA200500032A1 (ru) 2005-08-25
AU2003271815B2 (en) 2009-03-12
PL375309A1 (en) 2005-11-28
RS20050018A (en) 2007-06-04
TW200410957A (en) 2004-07-01
EP1525198B1 (fr) 2005-12-07

Similar Documents

Publication Publication Date Title
EP1558615B8 (en) Purine compounds and use thereof as cannabinoid receptor ligands
AU2003286263A1 (en) Complexes of receptors
HK1074439A1 (en) Quinoline derivatives and their use as 5-ht6 ligands
IL169112A0 (en) Phosphonooxy quinazoline derivatives and their pharmaceuitical use
AU2002232768A1 (en) Benzimidazole and pyridylimidazole derivatives as ligands for GABA receptors
IL162105A0 (en) New indole derivatives as factor xainhibitors
IL158807A0 (en) 5-ht receptor ligands and uses thereof
PL377215A1 (pl) Pochodne benzimidazolu oraz ich zastosowanie w charakterze ligandów receptora waniloidowego
IL139835A (en) Imidazolyl derivatives and their use as somatostatin receptor ligands
AU2003261974A1 (en) Amine compounds and use thereof
AU2167002A (en) Indoline derivatives and their use as 5-ht2 receptor ligands
SI1255751T1 (en) 1,3-dihydro-2h-indol-2-one derivatives and their use as ligands for v1b or v1b and v1a arginine-vasopressin receptors
IL162242A0 (en) Azaindolylalkylamine derivatives as5-hydroxytryptamine-6 ligands
ZA200500478B (en) Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors
AU2002362586A1 (en) Receptors and membrane-associated proteins
AU2003292508A1 (en) N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands
AU2002364699A1 (en) Receptors and membrane-associated proteins
AU2003222225A1 (en) Receptors and membrane-associated proteins
AU2002309970A1 (en) Receptors and membrane-associated proteins
AU2002346507A1 (en) Benzazepine derivatives and their use as 5-ht ligands
AU2002326910A1 (en) Receptors and membrane-associated proteins
AU2003224149A1 (en) N'-cyano-n-methyl-imidamide derivatives
AU2003272799A1 (en) Receptors and membrane-associated proteins
AU2003259007A1 (en) Use of urea variants as affinity ligands
AU2003205767A1 (en) Cyclic compounds and their use as complex ligands