ZA200500047B - Tumor-lysing virus growing selectively in tumor cells - Google Patents

Tumor-lysing virus growing selectively in tumor cells Download PDF

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Publication number
ZA200500047B
ZA200500047B ZA200500047A ZA200500047A ZA200500047B ZA 200500047 B ZA200500047 B ZA 200500047B ZA 200500047 A ZA200500047 A ZA 200500047A ZA 200500047 A ZA200500047 A ZA 200500047A ZA 200500047 B ZA200500047 B ZA 200500047B
Authority
ZA
South Africa
Prior art keywords
cancer
gene
virus
cells
tumor
Prior art date
Application number
ZA200500047A
Other languages
English (en)
Inventor
Toshiyoshi Fujiwara
Noriaki Tanaka
Satoru Kyo
Yoshiko Shirakiya
Takeshi Kawashima
Original Assignee
Kansai Tech Licensing Org Co
Toshiyoshi Fujiwara
Noriaki Tanaka
Satoru Kyo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kansai Tech Licensing Org Co, Toshiyoshi Fujiwara, Noriaki Tanaka, Satoru Kyo filed Critical Kansai Tech Licensing Org Co
Publication of ZA200500047B publication Critical patent/ZA200500047B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200500047A 2002-07-08 2005-01-04 Tumor-lysing virus growing selectively in tumor cells ZA200500047B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002198941A JP3867968B2 (ja) 2002-07-08 2002-07-08 腫瘍細胞において選択的に増殖する腫瘍融解ウイルス

Publications (1)

Publication Number Publication Date
ZA200500047B true ZA200500047B (en) 2006-05-31

Family

ID=30112441

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500047A ZA200500047B (en) 2002-07-08 2005-01-04 Tumor-lysing virus growing selectively in tumor cells

Country Status (15)

Country Link
US (1) US20060239967A1 (da)
EP (1) EP1553178B1 (da)
JP (1) JP3867968B2 (da)
KR (2) KR100947194B1 (da)
CN (1) CN100430476C (da)
AU (1) AU2003281310B2 (da)
CA (1) CA2491907C (da)
DK (1) DK1553178T3 (da)
ES (1) ES2455127T3 (da)
HK (1) HK1082958A1 (da)
NZ (1) NZ537631A (da)
PL (1) PL374644A1 (da)
PT (1) PT1553178E (da)
WO (1) WO2004005511A1 (da)
ZA (1) ZA200500047B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473418B2 (en) 2004-03-25 2009-01-06 Cell Genesys, Inc. Pan cancer oncolytic vectors and methods of use thereof
EP1745801A1 (en) * 2004-05-13 2007-01-24 Daiichi Pharmaceutical Co., Ltd. Method of inhibiting telomerase activity and inhibitor
CN100361710C (zh) * 2004-06-07 2008-01-16 成都康弘生物科技有限公司 肿瘤细胞专一表达免疫调节因子gm-csf的溶瘤性腺病毒重组体的构建及其应用
US7943373B2 (en) * 2004-09-29 2011-05-17 Oncolys Biopharma, Inc. Telomelysin/GFP-expressing recombinant virus
WO2006085689A1 (ja) * 2005-02-10 2006-08-17 Oncolys Biopharma, Inc. テロメライシン併用抗癌剤
JP5069871B2 (ja) * 2006-05-30 2012-11-07 シスメックス株式会社 新規な癌細胞検出試料調製用キット及びそれを用いた癌細胞検出用キット
WO2008065726A1 (fr) * 2006-11-29 2008-06-05 Oncolys Biopharma Inc. Agent contenant du télomelysin destiné à rompre la tolérance anti-tumorale
WO2008136213A1 (ja) * 2007-04-27 2008-11-13 Oncolys Biopharma Inc. 放射線増感増強剤
US20090181931A1 (en) * 2008-01-16 2009-07-16 Oncolys Biopharma, Inc. Antiviral activity of cidofovir against oncolytic viruses
CN102257156A (zh) 2008-12-18 2011-11-23 希森美康株式会社 血样中癌细胞的检测方法
JP6323978B2 (ja) 2010-12-24 2018-05-16 アークレイ株式会社 癌細胞の検出方法
CN106591368A (zh) * 2016-10-12 2017-04-26 郑州大学 携带il‑15r/il‑15融合基因的b亚群腺病毒11载体及其构建和用途
US11617765B2 (en) 2017-10-10 2023-04-04 Yamaguchi University Enhancer for T-cells or B-cells having memory function, malignant tumor recurrence inhibitor, and inducer for inducing memory function in T-cells or B-cells
JPWO2020230838A1 (da) * 2019-05-14 2020-11-19
BR112022007952A2 (pt) 2019-10-28 2022-10-04 Noile Immune Biotech Inc Medicamento para tratar câncer, medicamento de combinação, composição de medicamento, célula imunorresponsiva, veículo de entrega de ácido nucleico e produto

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999020108A1 (en) * 1997-10-23 1999-04-29 Uab Research Foundation Human papillomavirus vectors for the episomal transduction of host cells and method of making same
CA2362367C (en) * 1999-02-04 2004-08-03 Geron Corporation Telomerase reverse transcriptase transcriptional regulatory sequences
US6692736B2 (en) * 2000-03-24 2004-02-17 Cell Genesys, Inc. Cell-specific adenovirus vectors comprising an internal ribosome entry site
ATE412058T1 (de) 2000-03-24 2008-11-15 Cell Genesys Inc Interne ribosomenzugangsstelle-enthaltende zell- spezifische adenovirale vektoren
IL152420A0 (en) * 2001-02-23 2003-05-29 Novartis Ag Novel oncolytic adenoviral vectors
CN1177042C (zh) * 2001-04-12 2004-11-24 上海华康生物技术有限公司 共表达人p53基因和人细胞因子基因的重组腺病毒及其制法和用途
CN1195056C (zh) * 2001-07-12 2005-03-30 钱其军 一种在肿瘤细胞中特异性增殖及高效表达抗癌基因的重组病毒及其构建方法

Also Published As

Publication number Publication date
CA2491907A1 (en) 2004-01-15
DK1553178T3 (da) 2014-05-19
PL374644A1 (en) 2005-10-31
KR100947194B1 (ko) 2010-03-11
JP2004033186A (ja) 2004-02-05
AU2003281310A1 (en) 2004-01-23
KR20050075867A (ko) 2005-07-22
WO2004005511A1 (ja) 2004-01-15
JP3867968B2 (ja) 2007-01-17
ES2455127T3 (es) 2014-04-14
US20060239967A1 (en) 2006-10-26
HK1082958A1 (en) 2006-06-23
KR20090043589A (ko) 2009-05-06
CN1665927A (zh) 2005-09-07
EP1553178B1 (en) 2014-03-05
PT1553178E (pt) 2014-06-12
CN100430476C (zh) 2008-11-05
AU2003281310B2 (en) 2008-02-21
CA2491907C (en) 2013-03-19
EP1553178A1 (en) 2005-07-13
NZ537631A (en) 2007-05-31
EP1553178A4 (en) 2006-03-29

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