ZA200409396B - Transdermal analgesic systems with reduced abuse potential - Google Patents
Transdermal analgesic systems with reduced abuse potential Download PDFInfo
- Publication number
- ZA200409396B ZA200409396B ZA200409396A ZA200409396A ZA200409396B ZA 200409396 B ZA200409396 B ZA 200409396B ZA 200409396 A ZA200409396 A ZA 200409396A ZA 200409396 A ZA200409396 A ZA 200409396A ZA 200409396 B ZA200409396 B ZA 200409396B
- Authority
- ZA
- South Africa
- Prior art keywords
- antagonist
- analgesic
- reservoir
- fentanyl
- release rate
- Prior art date
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- 229940066690 talwin Drugs 0.000 description 1
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- 229920001897 terpolymer Polymers 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
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- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37511002P | 2002-04-23 | 2002-04-23 |
Publications (1)
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| ZA200409396B true ZA200409396B (en) | 2006-07-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200409396A ZA200409396B (en) | 2002-04-23 | 2004-11-22 | Transdermal analgesic systems with reduced abuse potential |
Country Status (20)
| Country | Link |
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| US (2) | US8440220B2 (zh) |
| EP (1) | EP1513507B1 (zh) |
| JP (2) | JP2005526839A (zh) |
| KR (1) | KR20050050615A (zh) |
| CN (2) | CN101406703A (zh) |
| AR (1) | AR039336A1 (zh) |
| AT (1) | ATE501712T1 (zh) |
| AU (2) | AU2003221752A1 (zh) |
| CA (1) | CA2496454A1 (zh) |
| DE (1) | DE60336394D1 (zh) |
| ES (1) | ES2361068T3 (zh) |
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| MX (1) | MXPA04010612A (zh) |
| NO (1) | NO20045034L (zh) |
| NZ (1) | NZ535971A (zh) |
| PE (1) | PE20031016A1 (zh) |
| TW (1) | TW200404581A (zh) |
| UY (1) | UY27773A1 (zh) |
| WO (1) | WO2003090729A1 (zh) |
| ZA (1) | ZA200409396B (zh) |
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| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| CA2440884C (en) * | 2001-03-16 | 2012-05-22 | Alza Corporation | Transdermal patch for administering fentanyl |
| AR039336A1 (es) * | 2002-04-23 | 2005-02-16 | Alza Corp | Sistemas analgesicos transdermicos con potencial de abuso reducido |
| EP2422775A3 (en) * | 2002-09-20 | 2012-04-18 | Alpharma, Inc. | Sequestering subunit and related compositions and methods |
| KR101159828B1 (ko) * | 2003-04-30 | 2012-07-04 | 퍼듀 퍼머 엘피 | 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형 |
| US7182955B2 (en) | 2003-04-30 | 2007-02-27 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
| US20040219195A1 (en) * | 2003-04-30 | 2004-11-04 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
| US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| KR20060120678A (ko) * | 2003-10-30 | 2006-11-27 | 알자 코포레이션 | 남용될 가능성이 감소된 경피용 진통제 시스템 |
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| HUE030128T2 (en) * | 2004-02-23 | 2017-04-28 | Euro Celtique Sa | Anti-abuse device for transdermal opioid administration |
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| US8195287B2 (en) * | 2007-12-05 | 2012-06-05 | The Invention Science Fund I, Llc | Method for electrical modulation of neural conduction |
| US8233976B2 (en) | 2007-12-05 | 2012-07-31 | The Invention Science Fund I, Llc | System for transdermal chemical modulation of neural activity |
| US8170660B2 (en) | 2007-12-05 | 2012-05-01 | The Invention Science Fund I, Llc | System for thermal modulation of neural activity |
| US8165668B2 (en) * | 2007-12-05 | 2012-04-24 | The Invention Science Fund I, Llc | Method for magnetic modulation of neural conduction |
| US8165669B2 (en) * | 2007-12-05 | 2012-04-24 | The Invention Science Fund I, Llc | System for magnetic modulation of neural conduction |
| US8170658B2 (en) | 2007-12-05 | 2012-05-01 | The Invention Science Fund I, Llc | System for electrical modulation of neural conduction |
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| US8180446B2 (en) * | 2007-12-05 | 2012-05-15 | The Invention Science Fund I, Llc | Method and system for cyclical neural modulation based on activity state |
| US8160695B2 (en) * | 2007-12-05 | 2012-04-17 | The Invention Science Fund I, Llc | System for chemical modulation of neural activity |
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-
2003
- 2003-04-22 AR ARP030101384A patent/AR039336A1/es not_active Application Discontinuation
- 2003-04-22 CA CA002496454A patent/CA2496454A1/en not_active Abandoned
- 2003-04-22 EP EP03718492A patent/EP1513507B1/en not_active Expired - Lifetime
- 2003-04-22 CN CNA2008101709946A patent/CN101406703A/zh active Pending
- 2003-04-22 TW TW092109405A patent/TW200404581A/zh unknown
- 2003-04-22 JP JP2003587366A patent/JP2005526839A/ja active Pending
- 2003-04-22 NZ NZ535971A patent/NZ535971A/en not_active IP Right Cessation
- 2003-04-22 AT AT03718492T patent/ATE501712T1/de not_active IP Right Cessation
- 2003-04-22 AU AU2003221752A patent/AU2003221752A1/en not_active Abandoned
- 2003-04-22 ES ES03718492T patent/ES2361068T3/es not_active Expired - Lifetime
- 2003-04-22 US US10/420,428 patent/US8440220B2/en not_active Expired - Fee Related
- 2003-04-22 CN CNA038146495A patent/CN1720028A/zh active Pending
- 2003-04-22 KR KR1020047017089A patent/KR20050050615A/ko active IP Right Grant
- 2003-04-22 DE DE60336394T patent/DE60336394D1/de not_active Expired - Lifetime
- 2003-04-22 WO PCT/US2003/012418 patent/WO2003090729A1/en active Application Filing
- 2003-04-22 MX MXPA04010612A patent/MXPA04010612A/es unknown
- 2003-04-23 PE PE2003000405A patent/PE20031016A1/es not_active Application Discontinuation
- 2003-04-23 UY UY27773A patent/UY27773A1/es not_active Application Discontinuation
-
2004
- 2004-10-21 IL IL16476004A patent/IL164760A0/xx unknown
- 2004-11-19 NO NO20045034A patent/NO20045034L/no not_active Application Discontinuation
- 2004-11-22 ZA ZA200409396A patent/ZA200409396B/en unknown
-
2009
- 2009-06-16 AU AU2009202407A patent/AU2009202407A1/en not_active Abandoned
-
2010
- 2010-10-18 JP JP2010233859A patent/JP5453211B2/ja not_active Expired - Fee Related
-
2013
- 2013-03-07 US US13/789,587 patent/US8747889B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050050615A (ko) | 2005-05-31 |
| US20130251760A1 (en) | 2013-09-26 |
| PE20031016A1 (es) | 2003-11-29 |
| UY27773A1 (es) | 2003-09-30 |
| US20040013716A1 (en) | 2004-01-22 |
| DE60336394D1 (de) | 2011-04-28 |
| AU2009202407A1 (en) | 2009-07-09 |
| TW200404581A (en) | 2004-04-01 |
| US8440220B2 (en) | 2013-05-14 |
| MXPA04010612A (es) | 2005-07-14 |
| NO20045034L (no) | 2005-01-19 |
| CN1720028A (zh) | 2006-01-11 |
| EP1513507A1 (en) | 2005-03-16 |
| JP2005526839A (ja) | 2005-09-08 |
| IL164760A0 (en) | 2005-12-18 |
| EP1513507B1 (en) | 2011-03-16 |
| AR039336A1 (es) | 2005-02-16 |
| AU2003221752A1 (en) | 2003-11-10 |
| ATE501712T1 (de) | 2011-04-15 |
| CN101406703A (zh) | 2009-04-15 |
| US8747889B2 (en) | 2014-06-10 |
| ES2361068T3 (es) | 2011-06-13 |
| JP5453211B2 (ja) | 2014-03-26 |
| JP2011057684A (ja) | 2011-03-24 |
| CA2496454A1 (en) | 2003-11-06 |
| NZ535971A (en) | 2007-07-27 |
| WO2003090729A1 (en) | 2003-11-06 |
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