ZA200405328B - Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis - Google Patents

Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis Download PDF

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Publication number
ZA200405328B
ZA200405328B ZA200405328A ZA200405328A ZA200405328B ZA 200405328 B ZA200405328 B ZA 200405328B ZA 200405328 A ZA200405328 A ZA 200405328A ZA 200405328 A ZA200405328 A ZA 200405328A ZA 200405328 B ZA200405328 B ZA 200405328B
Authority
ZA
South Africa
Prior art keywords
synthetic
oligopeptides
mmp
oligopeptide
metastasis
Prior art date
Application number
ZA200405328A
Other languages
English (en)
Inventor
Rath Matthias
Shirang Netke
Aleksandra Niedzwiecki
Original Assignee
Rath Matthias
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rath Matthias filed Critical Rath Matthias
Publication of ZA200405328B publication Critical patent/ZA200405328B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200405328A 2002-01-23 2004-07-05 Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis ZA200405328B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35131702P 2002-01-23 2002-01-23

Publications (1)

Publication Number Publication Date
ZA200405328B true ZA200405328B (en) 2006-03-29

Family

ID=27613485

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200405328A ZA200405328B (en) 2002-01-23 2004-07-05 Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis

Country Status (22)

Country Link
US (1) US8012935B2 (lv)
EP (1) EP1468085B1 (lv)
JP (1) JP2005515262A (lv)
KR (1) KR20040077764A (lv)
CN (2) CN1622992A (lv)
AT (1) ATE425247T1 (lv)
BR (1) BR0302819A (lv)
CA (1) CA2472775A1 (lv)
DE (1) DE60326539D1 (lv)
EE (1) EE200400030A (lv)
ES (1) ES2324027T3 (lv)
HR (1) HRP20040732A2 (lv)
IL (1) IL162714A0 (lv)
LV (2) LV13289B (lv)
MX (1) MXPA04007170A (lv)
NO (1) NO20034146L (lv)
NZ (1) NZ533738A (lv)
PL (1) PL209827B1 (lv)
RU (1) RU2346043C2 (lv)
WO (1) WO2003062413A1 (lv)
YU (1) YU76403A (lv)
ZA (1) ZA200405328B (lv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856598B1 (fr) * 2003-06-25 2005-10-28 Inst Nat Sante Rech Med Peptides derives de la proteine mmp-2 et leur utilisation en immunotherapie antitumorale
JP4911950B2 (ja) * 2005-11-07 2012-04-04 晃 伊東 Mmp−1の部分ペプチドを用いた癌浸潤・転移阻害薬
US20120100111A1 (en) * 2009-03-06 2012-04-26 Universite Paris Descartes Method for treating cancer
US8593732B1 (en) * 2010-01-23 2013-11-26 Lightsmyth Technologies, Inc. Partially metallized total internal reflection immersion grating
US8003110B1 (en) * 2011-01-24 2011-08-23 Matthias W. Rath Metalloproteinase oligopeptides and their therapeutic use
EP2649985A1 (en) * 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (III)
US20140017267A1 (en) * 2012-07-13 2014-01-16 Matthias W Rath Metalloproteinase oligopeptides and their therapeutic use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280106A (en) 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
GB8817075D0 (en) * 1988-07-18 1988-08-24 Raychem Ltd Oscillation suppressor
US5646027A (en) * 1994-09-08 1997-07-08 Warner-Lambert Company Process for the production of gelatinase catalytic domain protein
EP2275552B1 (en) 1999-10-29 2015-09-09 GlaxoSmithKline Biologicals SA Neisserial antigenic peptides

Also Published As

Publication number Publication date
NO20034146D0 (no) 2003-09-17
EP1468085A1 (en) 2004-10-20
EP1468085B1 (en) 2009-03-11
IL162714A0 (en) 2005-11-20
CA2472775A1 (en) 2003-07-31
WO2003062413A1 (en) 2003-07-31
MXPA04007170A (es) 2004-10-29
CN101007844A (zh) 2007-08-01
EE200400030A (et) 2004-04-15
US20030139345A1 (en) 2003-07-24
JP2005515262A (ja) 2005-05-26
RU2346043C2 (ru) 2009-02-10
LV13419B (en) 2006-09-20
ATE425247T1 (de) 2009-03-15
NZ533738A (en) 2006-03-31
HRP20040732A2 (en) 2005-06-30
LV13289B (en) 2005-11-20
DE60326539D1 (de) 2009-04-23
KR20040077764A (ko) 2004-09-06
CN1622992A (zh) 2005-06-01
PL371254A1 (en) 2005-06-13
ES2324027T3 (es) 2009-07-29
YU76403A (sh) 2006-05-25
RU2004125599A (ru) 2005-07-10
BR0302819A (pt) 2004-04-27
NO20034146L (no) 2003-10-28
US8012935B2 (en) 2011-09-06
PL209827B1 (pl) 2011-10-31

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