ATE425247T1 - Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen - Google Patents

Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen

Info

Publication number
ATE425247T1
ATE425247T1 AT03702506T AT03702506T ATE425247T1 AT E425247 T1 ATE425247 T1 AT E425247T1 AT 03702506 T AT03702506 T AT 03702506T AT 03702506 T AT03702506 T AT 03702506T AT E425247 T1 ATE425247 T1 AT E425247T1
Authority
AT
Austria
Prior art keywords
metastasis
cancer invasion
therapeutic use
preventive
synthetic peptides
Prior art date
Application number
AT03702506T
Other languages
English (en)
Inventor
Matthias Rath
Shrirang Netke
Aleksandra Niedzwiecki
Original Assignee
Matthias Rath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath filed Critical Matthias Rath
Application granted granted Critical
Publication of ATE425247T1 publication Critical patent/ATE425247T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03702506T 2002-01-23 2003-01-23 Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen ATE425247T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35131702P 2002-01-23 2002-01-23

Publications (1)

Publication Number Publication Date
ATE425247T1 true ATE425247T1 (de) 2009-03-15

Family

ID=27613485

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03702506T ATE425247T1 (de) 2002-01-23 2003-01-23 Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen

Country Status (22)

Country Link
US (1) US8012935B2 (de)
EP (1) EP1468085B1 (de)
JP (1) JP2005515262A (de)
KR (1) KR20040077764A (de)
CN (2) CN101007844A (de)
AT (1) ATE425247T1 (de)
BR (1) BR0302819A (de)
CA (1) CA2472775A1 (de)
DE (1) DE60326539D1 (de)
EE (1) EE200400030A (de)
ES (1) ES2324027T3 (de)
HR (1) HRP20040732A2 (de)
IL (1) IL162714A0 (de)
LV (2) LV13289B (de)
MX (1) MXPA04007170A (de)
NO (1) NO20034146L (de)
NZ (1) NZ533738A (de)
PL (1) PL209827B1 (de)
RU (1) RU2346043C2 (de)
WO (1) WO2003062413A1 (de)
YU (1) YU76403A (de)
ZA (1) ZA200405328B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856598B1 (fr) * 2003-06-25 2005-10-28 Inst Nat Sante Rech Med Peptides derives de la proteine mmp-2 et leur utilisation en immunotherapie antitumorale
JP4911950B2 (ja) * 2005-11-07 2012-04-04 晃 伊東 Ｍｍｐ−１の部分ペプチドを用いた癌浸潤・転移阻害薬
EP2403508B1 (de) * 2009-03-06 2015-10-28 Université Paris Descartes Verfahren zur krebsbehandlung mit konditioniertem kulturmedium aus zahnfleisch-fibroblasten
US8593732B1 (en) * 2010-01-23 2013-11-26 Lightsmyth Technologies, Inc. Partially metallized total internal reflection immersion grating
US8003110B1 (en) * 2011-01-24 2011-08-23 Matthias W. Rath Metalloproteinase oligopeptides and their therapeutic use
EP2649985A1 (de) * 2012-04-13 2013-10-16 Lipotec, S.A. Verbindungen zur Hemmung neuronaler Exozytose (III)
US20140017267A1 (en) * 2012-07-13 2014-01-16 Matthias W Rath Metalloproteinase oligopeptides and their therapeutic use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280106A (en) * 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
GB8817075D0 (en) * 1988-07-18 1988-08-24 Raychem Ltd Oscillation suppressor
US5646027A (en) * 1994-09-08 1997-07-08 Warner-Lambert Company Process for the production of gelatinase catalytic domain protein
RU2281956C2 (ru) 1999-10-29 2006-08-20 Чирон С.Р.Л. Антигенные пептиды neisseria

Also Published As

Publication number Publication date
YU76403A (sh) 2006-05-25
CN1622992A (zh) 2005-06-01
NO20034146D0 (no) 2003-09-17
RU2346043C2 (ru) 2009-02-10
JP2005515262A (ja) 2005-05-26
ZA200405328B (en) 2006-03-29
PL371254A1 (en) 2005-06-13
ES2324027T3 (es) 2009-07-29
LV13419B (en) 2006-09-20
BR0302819A (pt) 2004-04-27
NO20034146L (no) 2003-10-28
LV13289B (en) 2005-11-20
DE60326539D1 (de) 2009-04-23
EP1468085A1 (de) 2004-10-20
WO2003062413A1 (en) 2003-07-31
NZ533738A (en) 2006-03-31
EE200400030A (et) 2004-04-15
CA2472775A1 (en) 2003-07-31
CN101007844A (zh) 2007-08-01
IL162714A0 (en) 2005-11-20
PL209827B1 (pl) 2011-10-31
KR20040077764A (ko) 2004-09-06
US8012935B2 (en) 2011-09-06
HRP20040732A2 (en) 2005-06-30
EP1468085B1 (de) 2009-03-11
MXPA04007170A (es) 2004-10-29
RU2004125599A (ru) 2005-07-10
US20030139345A1 (en) 2003-07-24

Similar Documents

Publication Publication Date Title
TW200501976A (en) Compositions containing peptide copper complexes and metalloproteinase inhibitors, and methods related thereto
MXPA04001033A (es) Compuesto de sanado para heridas y anti-cancer.
ATE333467T1 (de) Peptide zum einsatz in der behandlung von tumoren und anderen zuständen, die das entfernen oder zerstören von zellen erfordern
DK1140969T3 (da) Bindevævsvækstfaktorfragmenter og fremgangsmåder og anvendelser deraf
DE60217507D1 (de) Peptide für die behandlung von tumoren und anderen zuständen, die das entfernen oder zerstören von zellen erfordern
MX2009008270A (es) Polipeptido novedoso que tiene actividad anti-tumoral.
DK1483290T3 (da) Peptider og peptidmimetika, der har anti-proliferativ aktivitet og/eller forstærker nukleinsyrebeskadigende midler eller behandlinger
NO20041700L (no) Human koagulasjonsfaktor VII-polypeptider
HRP20050585A2 (en) Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof
ATE459644T1 (de) Verwendung von aspartic proteasen in den bereichen kosmetik und behandlung
ATE489462T1 (de) Antimikrobielles polypeptid und nutzung davon
ATE425247T1 (de) Synthetische peptide und ihre vorbeugende oder therapeutische anwendung für krebsinvasion und metastasen
DE60040089D1 (de) Menschliches homolog aus der familie der metalloproteasen
ATE531384T1 (de) Peptide aus dem plasminogenaktivator-hemmer 1 und ihre verwendung
ATE361914T1 (de) Cathepsincysteinproteaseinhibitoren und deren verwendung zur behandlung von entzündungen und immunerkrankungen
RU2014134287A (ru) Бифункциональный пептид
BR0113147A (pt) Proteìnas e peptìdeos do estresse e métodos de uso dos mesmos
BR0107458A (pt) Codificação de (poli)peptìdeos que tem atividades chips por meio de ácidos nucleicos
LT2004079A (en) Sythetic peptides and uses therof for the prevention and therapy of cancer invasion and metastasis
FR2858234B1 (fr) Nouvel agent anti-angiogenique et son utilisation, notamment dans le cadre du traitement des cancers
IL169256A (en) Polypeptide having metalloprotease activity, nucleic acid encoding it and pharmaceutical composition comprising it
NO20016341L (no) Inhibitorer for integrinet <alfa>v<beta>6
ATE544779T1 (de) Neue, die migration dendritischer zellen induzierende polypeptide, sowie medikamente und pharmazeutische zusammensetzungen, die diese enthalten
WO2002053172A3 (en) Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover
DE10293089D2 (de) Phosphinat-peptidanaloga als Inhibitoren der Procollagen-C-Proteinase (PCP) zur Behandlung von fibrotischen Erkrankungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1468085

Country of ref document: EP