ZA200403184B - Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. - Google Patents
Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. Download PDFInfo
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- ZA200403184B ZA200403184B ZA200403184A ZA200403184A ZA200403184B ZA 200403184 B ZA200403184 B ZA 200403184B ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 B ZA200403184 B ZA 200403184B
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- South Africa
- Prior art keywords
- vascular
- arterial graft
- venous
- methyl
- shunt
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
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| US34373201P | 2001-10-25 | 2001-10-25 |
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| ZA200403184B true ZA200403184B (en) | 2005-05-12 |
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| ZA200403184A ZA200403184B (en) | 2001-10-25 | 2004-04-28 | Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. |
Country Status (18)
Families Citing this family (29)
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| JP2005533019A (ja) * | 2002-05-13 | 2005-11-04 | ベス・イスラエル・ディーコニス・メディカル・センター | 移植不全を治療するための方法および組成物 |
| ATE533433T1 (de) | 2002-06-26 | 2011-12-15 | Cook Medical Technologies Llc | Stent-graft befestigung |
| US20050214343A1 (en) * | 2002-07-18 | 2005-09-29 | Patrice Tremble | Medical devices comprising a protein-tyrosine kinase inhibitor to inhibit restonosis |
| JP2006526652A (ja) * | 2003-06-03 | 2006-11-24 | ベス・イスラエル・ディーコニス・メディカル・センター | 血管狭窄を治療するための方法及び化合物 |
| WO2005095641A1 (en) * | 2004-03-03 | 2005-10-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 11 (map3k11) |
| US8399609B2 (en) | 2004-03-05 | 2013-03-19 | Regenerx Biopharmaceuticals, Inc. | Treating or preventing extracellular matrix build-up |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| WO2007033152A2 (en) * | 2005-09-12 | 2007-03-22 | Conor Medsystems, Inc. | Composition, system and method for modulating release kinetics in implantable drug delivery devices by modifying drug solubility |
| US20070196428A1 (en) | 2006-02-17 | 2007-08-23 | Thierry Glauser | Nitric oxide generating medical devices |
| JP5110559B2 (ja) * | 2006-11-24 | 2012-12-26 | 学校法人近畿大学 | 被覆ステント |
| WO2009076200A2 (en) | 2007-12-07 | 2009-06-18 | Vertex Pharmaceuticals Incorporated | Solid forms of 1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1h-benzo[d]imidazol-2-yl)urea |
| WO2009135125A2 (en) * | 2008-05-01 | 2009-11-05 | Bayer Schering Pharma Ag | Catheter balloon drug adherence techniques and methods |
| WO2010093889A2 (en) | 2009-02-13 | 2010-08-19 | Vertex Pharmaceuticals Incorporated | Solid forms of 2-(2, 4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide |
| US9265633B2 (en) | 2009-05-20 | 2016-02-23 | 480 Biomedical, Inc. | Drug-eluting medical implants |
| US8888840B2 (en) * | 2009-05-20 | 2014-11-18 | Boston Scientific Scimed, Inc. | Drug eluting medical implant |
| US9309347B2 (en) | 2009-05-20 | 2016-04-12 | Biomedical, Inc. | Bioresorbable thermoset polyester/urethane elastomers |
| US8992601B2 (en) | 2009-05-20 | 2015-03-31 | 480 Biomedical, Inc. | Medical implants |
| US20110319987A1 (en) | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
| CA3186201A1 (en) * | 2009-05-20 | 2010-11-25 | Lyra Therapeutics, Inc. | Self-expandable medical device comprising polymeric strands and coatings thereon |
| US8372133B2 (en) * | 2009-10-05 | 2013-02-12 | 480 Biomedical, Inc. | Polymeric implant delivery system |
| MX341342B (es) | 2011-01-14 | 2016-08-17 | Vertex Pharma | Formas solidas del inhibidor de girasa (r)-1-etil-3-[6-fluoro-5-[2 -(1-hidroxi-1-metil-etil) pirimidin-5-il]-7-(tetrahidrofuran-2-il) -1h-benzimidazol-2-il]urea. |
| KR101897952B1 (ko) | 2011-01-14 | 2018-09-12 | 스페로 트리넴, 인코포레이티드 | 피리미딘 자이라제 및 토포이소머라제 ｉｖ 억제제 |
| US9187953B2 (en) | 2011-03-23 | 2015-11-17 | Rytec Corporation | Side column configuration for overhead roll-up door assemblies |
| KR101941420B1 (ko) | 2011-06-20 | 2019-01-23 | 스페로 트리넴, 인코포레이티드 | 자이라제 및 토포이소머라제 억제제의 인산에스테르 |
| US9326951B2 (en) | 2011-06-28 | 2016-05-03 | Yale University | Cell-free tissue engineered vascular grafts |
| WO2014015105A1 (en) | 2012-07-18 | 2014-01-23 | Vertex Pharmaceuticals Incorporated | Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| PL3424920T3 (pl) | 2013-10-17 | 2020-11-16 | Vertex Pharmaceuticals Incorporated | Kokryształy (S)-N-metylo-8-(1-((2'-metylo-4’,6'-dideutero-[4,5'-bipirymidyn]-6-ylo)amino)propan-2-ylo)chinolino-4-karboksyamidu i ich deuterowane pochodne jako inhibitory DNA-PK |
| US11541149B2 (en) | 2015-12-11 | 2023-01-03 | Research Institute At Nationwide Children's Hospital | Systems and methods for optimized patient specific tissue engineering vascular grafts |
| US11628239B2 (en) | 2016-11-04 | 2023-04-18 | University Of Delaware | Method for protecting skeletonized blood vessels |
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|---|---|---|---|---|
| US4824436A (en) * | 1985-04-09 | 1989-04-25 | Harvey Wolinsky | Method for the prevention of restenosis |
| US5171217A (en) * | 1991-02-28 | 1992-12-15 | Indiana University Foundation | Method for delivery of smooth muscle cell inhibitors |
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US6306421B1 (en) * | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5354774A (en) * | 1992-12-24 | 1994-10-11 | Yale University | Inhibition of smooth muscle cell proliferation by 8-methoxypsoralen photoactivated by visible light |
| US5279565A (en) * | 1993-02-03 | 1994-01-18 | Localmed, Inc. | Intravascular treatment apparatus and method |
| US5788687A (en) * | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
| US5788979A (en) * | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
| US6306165B1 (en) * | 1996-09-13 | 2001-10-23 | Meadox Medicals | ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin |
| US6245760B1 (en) * | 1997-05-28 | 2001-06-12 | Aventis Pharmaceuticals Products, Inc | Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases |
| CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| EP1085880A2 (en) * | 1998-06-11 | 2001-03-28 | Cerus Corporation | Use of alkylating compounds for inhibiting proliferation of arterial smooth muscle cells |
| CN1429222A (zh) * | 2000-02-17 | 2003-07-09 | 安姆根有限公司 | 激酶抑制剂 |
| US20020156023A1 (en) * | 2000-12-06 | 2002-10-24 | Tularik Inc. | Lometrexol combination therapy |
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
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- 2002-10-25 IL IL16158302A patent/IL161583A0/xx unknown
- 2002-10-25 CN CNA028211502A patent/CN1635858A/zh active Pending
- 2002-10-25 EP EP02784295A patent/EP1441749A4/en not_active Withdrawn
- 2002-10-25 US US10/280,576 patent/US20040044405A1/en not_active Abandoned
- 2002-10-25 WO PCT/US2002/034344 patent/WO2003034938A2/en active Application Filing
- 2002-10-25 MX MXPA04003906A patent/MXPA04003906A/es not_active Application Discontinuation
- 2002-10-25 BR BRPI0213497-7A patent/BR0213497A/pt not_active IP Right Cessation
- 2002-10-25 CA CA002464093A patent/CA2464093A1/en not_active Abandoned
- 2002-10-25 JP JP2003537510A patent/JP2006519623A/ja active Pending
- 2002-10-25 HU HU0402036A patent/HUP0402036A3/hu unknown
- 2002-10-25 KR KR10-2004-7006059A patent/KR20040051618A/ko not_active Application Discontinuation
-
2004
- 2004-04-23 EC EC2004005085A patent/ECSP045085A/es unknown
- 2004-04-28 ZA ZA200403184A patent/ZA200403184B/en unknown
- 2004-05-24 NO NO20042133A patent/NO20042133L/no not_active Application Discontinuation
- 2004-05-25 CO CO04048129A patent/CO5580792A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003034938A3 (en) | 2003-11-13 |
| IL161583A0 (en) | 2004-09-27 |
| BR0213497A (pt) | 2006-05-23 |
| MXPA04003906A (es) | 2005-02-17 |
| NZ532593A (en) | 2007-11-30 |
| HUP0402036A2 (hu) | 2005-02-28 |
| US20040044405A1 (en) | 2004-03-04 |
| WO2003034938A2 (en) | 2003-05-01 |
| HUP0402036A3 (en) | 2008-04-28 |
| CO5580792A2 (es) | 2005-11-30 |
| EP1441749A4 (en) | 2010-05-19 |
| NO20042133L (no) | 2004-07-09 |
| CA2464093A1 (en) | 2003-05-01 |
| JP2006519623A (ja) | 2006-08-31 |
| KR20040051618A (ko) | 2004-06-18 |
| ECSP045085A (es) | 2004-07-23 |
| EP1441749A2 (en) | 2004-08-04 |
| RU2004116068A (ru) | 2005-03-20 |
| CN1635858A (zh) | 2005-07-06 |
| PL374315A1 (en) | 2005-10-03 |
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