ZA200402288B - Neuroprotective treatment methods using selective iNOS inhibitors - Google Patents
Neuroprotective treatment methods using selective iNOS inhibitors Download PDFInfo
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- ZA200402288B ZA200402288B ZA200402288A ZA200402288A ZA200402288B ZA 200402288 B ZA200402288 B ZA 200402288B ZA 200402288 A ZA200402288 A ZA 200402288A ZA 200402288 A ZA200402288 A ZA 200402288A ZA 200402288 B ZA200402288 B ZA 200402288B
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- 125000001422 pyrrolinyl group Chemical group 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000024875 regulation of vasodilation Effects 0.000 description 1
- 210000003994 retinal ganglion cell Anatomy 0.000 description 1
- 125000003003 spiro group Chemical group 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 125000004213 tert-butoxy group Chemical group [H]C([H])([H])C(O*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000001984 thiazolidinyl group Chemical group 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/961,521 US20030119826A1 (en) | 2001-09-24 | 2001-09-24 | Neuroprotective treatment methods using selective iNOS inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200402288B true ZA200402288B (en) | 2006-12-27 |
Family
ID=25504581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200402288A ZA200402288B (en) | 2001-09-24 | 2004-03-23 | Neuroprotective treatment methods using selective iNOS inhibitors |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030119826A1 (https=) |
| EP (1) | EP1429752A1 (https=) |
| JP (1) | JP2005508910A (https=) |
| KR (1) | KR20040039394A (https=) |
| CN (1) | CN1556698A (https=) |
| AU (1) | AU2002327042A2 (https=) |
| BR (1) | BR0212989A (https=) |
| CA (1) | CA2455989A1 (https=) |
| IL (1) | IL161005A0 (https=) |
| MX (1) | MXPA04002710A (https=) |
| PL (1) | PL371774A1 (https=) |
| WO (1) | WO2003026638A1 (https=) |
| ZA (1) | ZA200402288B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8314124B2 (en) | 2004-02-06 | 2012-11-20 | Active Biotech Ab | Crystalline salts of quinoline compounds and methods for preparing them |
| US7884208B2 (en) * | 2005-10-19 | 2011-02-08 | Teva Pharmaceutical Industries, Ltd. | Crystals of laquinimod sodium, and process for the manufacture thereof |
| RS52169B (sr) * | 2006-06-12 | 2012-08-31 | Teva Pharmaceutical Industries Limited | Stabilni preparati lakvinimoda |
| ES2445451T3 (es) | 2007-12-20 | 2014-03-03 | Teva Pharmaceutical Industries, Ltd. | Preparaciones estables de laquinimod |
| KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 ２―옥소―１,２―다이하이드로―퀴놀린 조절제 |
| ME02414B (me) * | 2009-07-30 | 2016-09-20 | Teva Pharma | Tretman kronove bolesti lakvinimodom |
| PT2467372T (pt) * | 2009-08-10 | 2016-08-23 | Teva Pharma | Tratamento de distúrbios relacionados com bdnf usando laquinimod |
| CN106344576A (zh) | 2011-10-12 | 2017-01-25 | 泰华制药工业有限公司 | 以拉喹莫德和芬戈莫德的组合治疗多发性硬化症 |
| CN106063787A (zh) | 2012-02-03 | 2016-11-02 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| JP2015535287A (ja) | 2012-11-07 | 2015-12-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドのアミン塩 |
| NZ630427A (en) | 2013-03-14 | 2017-06-30 | Teva Pharma | Crystals of laquinimod sodium and improved process for the manufacture thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1265859T3 (da) * | 2000-03-24 | 2006-05-01 | Pharmacia Corp | Amidinoforbindelser der er nyttige som nitrogenoxidsyntaseinhibitorer |
| AR032318A1 (es) * | 2000-04-13 | 2003-11-05 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa |
-
2001
- 2001-09-24 US US09/961,521 patent/US20030119826A1/en not_active Abandoned
-
2002
- 2002-09-24 PL PL02371774A patent/PL371774A1/xx not_active Application Discontinuation
- 2002-09-24 MX MXPA04002710A patent/MXPA04002710A/es unknown
- 2002-09-24 EP EP02761804A patent/EP1429752A1/en not_active Withdrawn
- 2002-09-24 AU AU2002327042A patent/AU2002327042A2/en not_active Abandoned
- 2002-09-24 CN CNA028185935A patent/CN1556698A/zh active Pending
- 2002-09-24 JP JP2003530275A patent/JP2005508910A/ja active Pending
- 2002-09-24 BR BR0212989-2A patent/BR0212989A/pt not_active IP Right Cessation
- 2002-09-24 CA CA002455989A patent/CA2455989A1/en not_active Abandoned
- 2002-09-24 WO PCT/US2002/030214 patent/WO2003026638A1/en not_active Ceased
- 2002-09-24 KR KR10-2004-7004170A patent/KR20040039394A/ko not_active Withdrawn
- 2002-09-24 IL IL16100502A patent/IL161005A0/xx unknown
-
2004
- 2004-03-23 ZA ZA200402288A patent/ZA200402288B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL371774A1 (en) | 2005-06-27 |
| IL161005A0 (en) | 2004-08-31 |
| WO2003026638A1 (en) | 2003-04-03 |
| MXPA04002710A (es) | 2004-07-05 |
| BR0212989A (pt) | 2005-04-26 |
| EP1429752A1 (en) | 2004-06-23 |
| CN1556698A (zh) | 2004-12-22 |
| AU2002327042A2 (en) | 2003-04-07 |
| US20030119826A1 (en) | 2003-06-26 |
| CA2455989A1 (en) | 2003-04-03 |
| JP2005508910A (ja) | 2005-04-07 |
| KR20040039394A (ko) | 2004-05-10 |
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