JP2005506986A5 - - Google Patents
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- Publication number
- JP2005506986A5 JP2005506986A5 JP2003530303A JP2003530303A JP2005506986A5 JP 2005506986 A5 JP2005506986 A5 JP 2005506986A5 JP 2003530303 A JP2003530303 A JP 2003530303A JP 2003530303 A JP2003530303 A JP 2003530303A JP 2005506986 A5 JP2005506986 A5 JP 2005506986A5
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- JP
- Japan
- Prior art keywords
- product
- added
- nmr
- mmol
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 0 CC(*C*=*CC([*+])(**)N)=N Chemical compound CC(*C*=*CC([*+])(**)N)=N 0.000 description 15
- NPWIISKQJVBXLO-NSHDSACASA-N CC(C)(C)OC(N([C@@H](CC=C)CCCC1)C1=O)=O Chemical compound CC(C)(C)OC(N([C@@H](CC=C)CCCC1)C1=O)=O NPWIISKQJVBXLO-NSHDSACASA-N 0.000 description 1
- VQGCWTDMOOOHCH-PFPYCLJUSA-N CC(NC/C(/F)=C/CC[C@@H](C(O)=O)N)=N Chemical compound CC(NC/C(/F)=C/CC[C@@H](C(O)=O)N)=N VQGCWTDMOOOHCH-PFPYCLJUSA-N 0.000 description 1
- VQGCWTDMOOOHCH-DKCNVOGISA-N CC(NC/C(/F)=C\CC[C@@H](C(O)=O)N)=N Chemical compound CC(NC/C(/F)=C\CC[C@@H](C(O)=O)N)=N VQGCWTDMOOOHCH-DKCNVOGISA-N 0.000 description 1
- NGISQCDLIMTOPW-SSDOTTSWSA-N O=C1ON=C2N1[C@@H](CCBr)CCCC2 Chemical compound O=C1ON=C2N1[C@@H](CCBr)CCCC2 NGISQCDLIMTOPW-SSDOTTSWSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/961,816 US20030109522A1 (en) | 2001-09-24 | 2001-09-24 | Ophthalmologic treatment methods using selective iNOS inhibitors |
| PCT/US2002/030213 WO2003026668A1 (en) | 2001-09-24 | 2002-09-24 | Ophthalmologic treatment methods using selective inos inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005506986A JP2005506986A (ja) | 2005-03-10 |
| JP2005506986A5 true JP2005506986A5 (https=) | 2006-01-12 |
Family
ID=25505060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003530303A Withdrawn JP2005506986A (ja) | 2001-09-24 | 2002-09-24 | 選択的ｉｎｏｓ阻害剤を用いる眼科治療方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030109522A1 (https=) |
| EP (1) | EP1429777A4 (https=) |
| JP (1) | JP2005506986A (https=) |
| KR (1) | KR20040039393A (https=) |
| CN (1) | CN1556707A (https=) |
| AU (1) | AU2002327041A2 (https=) |
| BR (1) | BR0212991A (https=) |
| CA (1) | CA2455910A1 (https=) |
| IL (1) | IL161004A0 (https=) |
| MX (1) | MXPA04002711A (https=) |
| PL (1) | PL369338A1 (https=) |
| WO (1) | WO2003026668A1 (https=) |
| ZA (1) | ZA200402285B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1884237B1 (en) * | 2005-05-17 | 2010-12-08 | Santen Pharmaceutical Co., Ltd. | Amidino derivatives for use in the prevention or treatment of glaucoma |
| ES2965961T3 (es) | 2016-03-07 | 2024-04-17 | Centro Nac De Investigaciones Cardiovasculares Carlos Iii F S P | Uso de inhibidores selectivos de INOS para el tratamiento de aneurismas de la aorta torácica (TAA) en un sujeto |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5132453A (en) * | 1991-03-22 | 1992-07-21 | Cornell Research Foundation, Inc. | N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body |
| GB9127376D0 (en) * | 1991-12-24 | 1992-02-19 | Wellcome Found | Amidino derivatives |
| US5684008A (en) * | 1994-11-09 | 1997-11-04 | G. D. Searle & Co. | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors |
| US5830917A (en) * | 1995-09-11 | 1998-11-03 | G. D. Searle & Co. | L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors |
| US5945408A (en) * | 1996-03-06 | 1999-08-31 | G.D. Searle & Co. | Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors |
| US5981511A (en) * | 1996-03-06 | 1999-11-09 | G.D. Searle & Co. | Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors |
| GB9811599D0 (en) * | 1998-05-30 | 1998-07-29 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
| DK1265859T3 (da) * | 2000-03-24 | 2006-05-01 | Pharmacia Corp | Amidinoforbindelser der er nyttige som nitrogenoxidsyntaseinhibitorer |
| AR032318A1 (es) * | 2000-04-13 | 2003-11-05 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa |
-
2001
- 2001-09-24 US US09/961,816 patent/US20030109522A1/en not_active Abandoned
-
2002
- 2002-09-24 AU AU2002327041A patent/AU2002327041A2/en not_active Abandoned
- 2002-09-24 EP EP02761803A patent/EP1429777A4/en not_active Withdrawn
- 2002-09-24 IL IL16100402A patent/IL161004A0/xx unknown
- 2002-09-24 MX MXPA04002711A patent/MXPA04002711A/es unknown
- 2002-09-24 CN CNA028185854A patent/CN1556707A/zh active Pending
- 2002-09-24 KR KR10-2004-7004169A patent/KR20040039393A/ko not_active Withdrawn
- 2002-09-24 CA CA002455910A patent/CA2455910A1/en not_active Abandoned
- 2002-09-24 JP JP2003530303A patent/JP2005506986A/ja not_active Withdrawn
- 2002-09-24 WO PCT/US2002/030213 patent/WO2003026668A1/en not_active Ceased
- 2002-09-24 BR BR0212991-4A patent/BR0212991A/pt not_active IP Right Cessation
- 2002-09-24 PL PL02369338A patent/PL369338A1/xx not_active Application Discontinuation
-
2004
- 2004-03-23 ZA ZA200402285A patent/ZA200402285B/xx unknown
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| JP2005506986A5 (https=) | ||
| JP2005506986A (ja) | 選択的ｉｎｏｓ阻害剤を用いる眼科治療方法 | |
| US20040127569A1 (en) | Methods for treatment and prevention of gastrointestinal conditions | |
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