KR20040039393A - 선택적 ｉｎｏｓ 억제제를 사용한 안과적 치료 방법 - Google Patents

선택적 ｉｎｏｓ 억제제를 사용한 안과적 치료 방법 Download PDF

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Publication number
KR20040039393A
KR20040039393A KR10-2004-7004169A KR20047004169A KR20040039393A KR 20040039393 A KR20040039393 A KR 20040039393A KR 20047004169 A KR20047004169 A KR 20047004169A KR 20040039393 A KR20040039393 A KR 20040039393A
Authority
KR
South Korea
Prior art keywords
alkyl
halo
alkoxy
product
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR10-2004-7004169A
Other languages
English (en)
Korean (ko)
Inventor
매닝파멜라티
코너제인알
Original Assignee
파마시아 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 파마시아 코포레이션 filed Critical 파마시아 코포레이션
Publication of KR20040039393A publication Critical patent/KR20040039393A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-7004169A 2001-09-24 2002-09-24 선택적 ｉｎｏｓ 억제제를 사용한 안과적 치료 방법 Withdrawn KR20040039393A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/961,816 2001-09-24
US09/961,816 US20030109522A1 (en) 2001-09-24 2001-09-24 Ophthalmologic treatment methods using selective iNOS inhibitors
PCT/US2002/030213 WO2003026668A1 (en) 2001-09-24 2002-09-24 Ophthalmologic treatment methods using selective inos inhibitors

Publications (1)

Publication Number Publication Date
KR20040039393A true KR20040039393A (ko) 2004-05-10

Family

ID=25505060

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7004169A Withdrawn KR20040039393A (ko) 2001-09-24 2002-09-24 선택적 ｉｎｏｓ 억제제를 사용한 안과적 치료 방법

Country Status (13)

Country Link
US (1) US20030109522A1 (https=)
EP (1) EP1429777A4 (https=)
JP (1) JP2005506986A (https=)
KR (1) KR20040039393A (https=)
CN (1) CN1556707A (https=)
AU (1) AU2002327041A2 (https=)
BR (1) BR0212991A (https=)
CA (1) CA2455910A1 (https=)
IL (1) IL161004A0 (https=)
MX (1) MXPA04002711A (https=)
PL (1) PL369338A1 (https=)
WO (1) WO2003026668A1 (https=)
ZA (1) ZA200402285B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1884237B1 (en) * 2005-05-17 2010-12-08 Santen Pharmaceutical Co., Ltd. Amidino derivatives for use in the prevention or treatment of glaucoma
ES2965961T3 (es) 2016-03-07 2024-04-17 Centro Nac De Investigaciones Cardiovasculares Carlos Iii F S P Uso de inhibidores selectivos de INOS para el tratamiento de aneurismas de la aorta torácica (TAA) en un sujeto

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132453A (en) * 1991-03-22 1992-07-21 Cornell Research Foundation, Inc. N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
US5684008A (en) * 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US5830917A (en) * 1995-09-11 1998-11-03 G. D. Searle & Co. L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
US5981511A (en) * 1996-03-06 1999-11-09 G.D. Searle & Co. Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors
GB9811599D0 (en) * 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
DK1265859T3 (da) * 2000-03-24 2006-05-01 Pharmacia Corp Amidinoforbindelser der er nyttige som nitrogenoxidsyntaseinhibitorer
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa

Also Published As

Publication number Publication date
BR0212991A (pt) 2004-08-17
CA2455910A1 (en) 2003-04-03
ZA200402285B (en) 2005-06-13
WO2003026668A1 (en) 2003-04-03
AU2002327041A2 (en) 2003-04-07
IL161004A0 (en) 2004-08-31
EP1429777A4 (en) 2005-06-22
PL369338A1 (en) 2005-04-18
EP1429777A1 (en) 2004-06-23
MXPA04002711A (es) 2004-07-05
CN1556707A (zh) 2004-12-22
US20030109522A1 (en) 2003-06-12
JP2005506986A (ja) 2005-03-10

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20040322

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid