BR0212991A - Métodos de tratamento oftalmológico utilizando inibidores seletivos de inos - Google Patents

Métodos de tratamento oftalmológico utilizando inibidores seletivos de inos

Info

Publication number
BR0212991A
BR0212991A BR0212991-4A BR0212991A BR0212991A BR 0212991 A BR0212991 A BR 0212991A BR 0212991 A BR0212991 A BR 0212991A BR 0212991 A BR0212991 A BR 0212991A
Authority
BR
Brazil
Prior art keywords
treatment methods
inos inhibitors
ophthalmic treatment
selective inos
selective
Prior art date
Application number
BR0212991-4A
Other languages
English (en)
Inventor
Pamela T Manning
Jane R Connor
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0212991A publication Critical patent/BR0212991A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"MéTODOS DE TRATAMENTO OFTALMOLóGICO UTILIZANDO INIBIDORES SELETIVOS DE INOS". A presente invenção refere-se a métodos terapêuticos para a prevenção e tratamento de condições oftalmológicas, os métodos incluindo a administração ao indivíduo necessitando do mesmo de um inibidor seletivo de sintase de óxido nítrico induzível.
BR0212991-4A 2001-09-24 2002-09-24 Métodos de tratamento oftalmológico utilizando inibidores seletivos de inos BR0212991A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/961,816 US20030109522A1 (en) 2001-09-24 2001-09-24 Ophthalmologic treatment methods using selective iNOS inhibitors
PCT/US2002/030213 WO2003026668A1 (en) 2001-09-24 2002-09-24 Ophthalmologic treatment methods using selective inos inhibitors

Publications (1)

Publication Number Publication Date
BR0212991A true BR0212991A (pt) 2004-08-17

Family

ID=25505060

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212991-4A BR0212991A (pt) 2001-09-24 2002-09-24 Métodos de tratamento oftalmológico utilizando inibidores seletivos de inos

Country Status (13)

Country Link
US (1) US20030109522A1 (pt)
EP (1) EP1429777A4 (pt)
JP (1) JP2005506986A (pt)
KR (1) KR20040039393A (pt)
CN (1) CN1556707A (pt)
AU (1) AU2002327041A2 (pt)
BR (1) BR0212991A (pt)
CA (1) CA2455910A1 (pt)
IL (1) IL161004A0 (pt)
MX (1) MXPA04002711A (pt)
PL (1) PL369338A1 (pt)
WO (1) WO2003026668A1 (pt)
ZA (1) ZA200402285B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006018725D1 (de) * 2005-05-17 2011-01-20 Santen Pharmaceutical Co Ltd Amidin-derivate zur verwendung in der vorbeugung oder behandlung von glaukom
WO2017153023A1 (en) * 2016-03-07 2017-09-14 Cnic Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii In vitro method for identifying thoracic aortic aneurysms (taa) in a subject

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132453A (en) * 1991-03-22 1992-07-21 Cornell Research Foundation, Inc. N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
US5684008A (en) * 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US5830917A (en) * 1995-09-11 1998-11-03 G. D. Searle & Co. L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors
US5981511A (en) * 1996-03-06 1999-11-09 G.D. Searle & Co. Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
GB9811599D0 (en) * 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
AU2001247745B2 (en) * 2000-03-24 2006-08-31 Pharmacia Corporation Amidino compounds useful as nitric oxide synthase inhibitors
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa

Also Published As

Publication number Publication date
JP2005506986A (ja) 2005-03-10
IL161004A0 (en) 2004-08-31
PL369338A1 (en) 2005-04-18
AU2002327041A2 (en) 2003-04-07
WO2003026668A1 (en) 2003-04-03
ZA200402285B (en) 2005-06-13
EP1429777A1 (en) 2004-06-23
US20030109522A1 (en) 2003-06-12
EP1429777A4 (en) 2005-06-22
CA2455910A1 (en) 2003-04-03
KR20040039393A (ko) 2004-05-10
CN1556707A (zh) 2004-12-22
MXPA04002711A (es) 2004-07-05

Similar Documents

Publication Publication Date Title
TW200510349A (en) Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
WO2007062093A3 (en) Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor
HUP0401867A2 (hu) A valproinsav-amid és a 2-valproénsav-amid származékainak használata a fájdalommal és a fejfájással járó betegségek kezelésére vagy megelőzésére
BR0309095A (pt) Uso de osteoprotegerina para o tratamento e/ou prevenção de doença fibrótica
EA200300560A1 (ru) Улучшенный способ лечения
CY1106155T1 (el) Χρηση παραγωγων 3-βενζολοφαινυλοξικων οξεων για την αντιμετωπιση διαταραχων του αμφιβληστροειδους
BR0310061A (pt) Métodos para o tratamento de doenças e condições respiratórias com um inibidor seletivo da inos e um inibidor da pde e suas composições
BRPI0411864A (pt) combinação de inibidores de src quinase e agentes quimioterápicos para o tratamento de doenças proliferativas
WO2001068053A3 (en) Methods and compositions for treating and preventing posterior segment ophthalmic disorders
BR0212989A (pt) Métodos para tratamento neuroprotetor usando inibidores de inos seletivos
WO2004014367A3 (en) Use of an amyloid beta vaccination in combination with a selective cox-2 inhibitor for the treatment of alzheimer's disease
WO2002039994A3 (en) Methods for the treatment and prevention of urinary stone disease
BR0008443A (pt) Inibidores de aminotransferaseaminoácido-dependente de cadeia ramificada e seuuso no tratamento da retinopatia diabética
BR0311903A (pt) Tratamento para depressão e ansiedade pela combinação de um inibidor de pde iv e um agente antidepressivo ou ansiolìtico
EP1262197A3 (en) Combination treatment for sleep disorders including sleep apnea
GB0020504D0 (en) Therapeutic method
WO2005055956A3 (en) Method for improving insulin sensitivity by administering an inhibitor of antitrypsin
BR0212991A (pt) Métodos de tratamento oftalmológico utilizando inibidores seletivos de inos
HK1081862A1 (en) Synergistic combination comprising roflumilast and (r,r)-formoterol
EP1297849A4 (en) CURATIVE AGENT FOR OPTICAL AND SIMILAR NERVE DISEASES
BR0311180A (pt) Métodos para o tratamento de doenças e condições respiratórias utilizando um inibidor seletivo da inos
SE0102887D0 (sv) New formulation
BR0313204A (pt) Métodos para tratamento e prevenção de condições gastrointestinais
RU2006101150A (ru) Композиции нестероидных противовоспалительных средств для лечения патологического ангиогенеза глаз
WO2003045322A3 (en) Method for treating and preventing pancreatitis

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1971 DE 14/10/2008.