ZA200402059B - Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same. - Google Patents
Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same. Download PDFInfo
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- ZA200402059B ZA200402059B ZA200402059A ZA200402059A ZA200402059B ZA 200402059 B ZA200402059 B ZA 200402059B ZA 200402059 A ZA200402059 A ZA 200402059A ZA 200402059 A ZA200402059 A ZA 200402059A ZA 200402059 B ZA200402059 B ZA 200402059B
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- ZA
- South Africa
- Prior art keywords
- formula
- compound
- tetrahydropyridine
- trifluoromethylphenyl
- ethyl
- Prior art date
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- 239000008194 pharmaceutical composition Substances 0.000 title claims description 4
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0113469A FR2831166B1 (fr) | 2001-10-18 | 2001-10-18 | Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200402059B true ZA200402059B (en) | 2005-03-15 |
Family
ID=8868455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200402059A ZA200402059B (en) | 2001-10-18 | 2004-03-15 | Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same. |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7326723B2 (de) |
| EP (1) | EP1438291B1 (de) |
| JP (2) | JP4524107B2 (de) |
| KR (1) | KR100935787B1 (de) |
| CN (2) | CN100335464C (de) |
| AT (1) | ATE303991T1 (de) |
| AU (1) | AU2002360117B2 (de) |
| BR (1) | BR0213359A (de) |
| CA (1) | CA2460822C (de) |
| DE (1) | DE60206068T2 (de) |
| EA (1) | EA007324B1 (de) |
| FR (1) | FR2831166B1 (de) |
| HK (1) | HK1065543A1 (de) |
| HU (1) | HUP0401713A3 (de) |
| IL (2) | IL160820A0 (de) |
| IS (1) | IS2486B (de) |
| MX (1) | MXPA04003568A (de) |
| NO (1) | NO326490B1 (de) |
| NZ (1) | NZ531846A (de) |
| PL (1) | PL368802A1 (de) |
| WO (1) | WO2003033466A1 (de) |
| ZA (1) | ZA200402059B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL370371A1 (en) | 2001-10-15 | 2005-05-16 | Janssen Pharmaceutica N.V. | Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage |
| US20060276465A1 (en) * | 2003-12-26 | 2006-12-07 | Eisai R&D Management Co., Ltd. | 1,2-di(cyclic) substituted benzene compounds |
| MY140489A (en) * | 2003-12-26 | 2009-12-31 | Eisai R&D Man Co Ltd | 1,2-di (cyclic) substituted benzene compounds |
| KR101274879B1 (ko) | 2004-12-20 | 2013-06-14 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 1-시클로프로필메틸-4-[2-(3,3,5,5-테트라메틸시클로헥실)페닐]피페라진의 염 및 결정 |
| US7410971B2 (en) | 2004-12-24 | 2008-08-12 | Eisai R&D Management Co., Ltd. | 1,2-di(cyclic)substituted benzene compounds |
| MY144974A (en) * | 2005-06-14 | 2011-11-30 | Eisai R&D Man Co Ltd | 1,2-di(cyclic) substituted benzene derivatives |
| US9493383B2 (en) | 2005-09-15 | 2016-11-15 | Lg Chem, Ltd. | Organic compound and organic light emitting device using the same |
| US8298683B2 (en) * | 2005-09-15 | 2012-10-30 | Lg Chem, Ltd. | Organic compound and organic light emitting device using the same |
| US9608205B2 (en) | 2005-09-15 | 2017-03-28 | Lg Chem, Ltd. | Organic compound and organic light emitting device using the same |
| CN107267384B (zh) * | 2008-06-05 | 2020-11-27 | 因维沃科学有限公司 | 用于高通量试验的三维组织 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3804878A (en) * | 1969-09-08 | 1974-04-16 | Ciba Geigy Corp | Hydrogenated araliphatic acids |
| DE69105786T2 (de) * | 1990-03-12 | 1995-04-27 | Yamanouchi Pharma Co Ltd | Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen. |
| FR2662442A1 (fr) * | 1990-05-23 | 1991-11-29 | Midy Spa | Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant. |
| ATE199721T1 (de) * | 1994-07-04 | 2001-03-15 | Takeda Chemical Industries Ltd | Phosphonsäure verbindungen imre herstellung und verwendung |
| FR2734819B1 (fr) * | 1995-05-31 | 1997-07-04 | Adir | Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant |
| FR2762514B1 (fr) * | 1997-04-29 | 1999-10-22 | Sanofi Sa | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation |
| FR2763847B1 (fr) * | 1997-05-28 | 2003-06-06 | Sanofi Sa | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 |
| US6070784A (en) * | 1998-07-08 | 2000-06-06 | The Boeing Company | Contact backup roller approach to FSW process |
| EP1226137B8 (de) * | 1999-10-22 | 2004-12-15 | Sanofi-Aventis | Phenyl- und pyridyl-tetrahydro-pyridine mit tnf inhibitorischer wirkung |
| DE60038911D1 (de) * | 1999-12-30 | 2008-06-26 | Lundbeck & Co As H | 4-Phenylpiperazinyl, -piperidinyl und -tetrahydropyridyl-Derivate als Dopamin D4-Antagonisten |
| FR2803593B1 (fr) * | 2000-01-06 | 2002-02-15 | Sanofi Synthelabo | Nouvelles tetrahydropyridines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| DE60220779T2 (de) * | 2001-04-20 | 2008-03-06 | Sanofi-Aventis | Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten |
| FR2823749B1 (fr) * | 2001-04-20 | 2004-02-20 | Sanofi Synthelabo | Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| JP3687912B2 (ja) * | 2002-08-29 | 2005-08-24 | 東芝テック株式会社 | プリンタユニット |
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2001
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2002
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- 2002-10-14 CN CNB028207548A patent/CN100335464C/zh not_active Expired - Fee Related
- 2002-10-14 WO PCT/FR2002/003508 patent/WO2003033466A1/fr active IP Right Grant
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- 2002-10-14 CN CNA2007101368627A patent/CN101096337A/zh active Pending
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2004
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-
2007
- 2007-12-18 US US11/958,476 patent/US7858824B2/en not_active Expired - Fee Related
-
2010
- 2010-02-18 JP JP2010033642A patent/JP2010120961A/ja not_active Withdrawn
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