ZA200308592B - Benzamidoacetonitriles and their use as antiparasitics. - Google Patents
Benzamidoacetonitriles and their use as antiparasitics. Download PDFInfo
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- ZA200308592B ZA200308592B ZA200308592A ZA200308592A ZA200308592B ZA 200308592 B ZA200308592 B ZA 200308592B ZA 200308592 A ZA200308592 A ZA 200308592A ZA 200308592 A ZA200308592 A ZA 200308592A ZA 200308592 B ZA200308592 B ZA 200308592B
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- South Africa
- Prior art keywords
- halo
- alkyl
- alkoxy
- alkylthio
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- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- IUBQJLUDMLPAGT-UHFFFAOYSA-N potassium bis(trimethylsilyl)amide Chemical compound C[Si](C)(C)N([K])[Si](C)(C)C IUBQJLUDMLPAGT-UHFFFAOYSA-N 0.000 description 1
- LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 description 1
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- 239000002244 precipitate Substances 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
- C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D335/16—Oxygen atoms, e.g. thioxanthones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH9192001 | 2001-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200308592B true ZA200308592B (en) | 2004-09-03 |
Family
ID=4548043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200308592A ZA200308592B (en) | 2001-05-15 | 2003-11-04 | Benzamidoacetonitriles and their use as antiparasitics. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7705044B2 (ko) |
| EP (1) | EP1390344B1 (ko) |
| JP (1) | JP4124661B2 (ko) |
| KR (1) | KR100628842B1 (ko) |
| CN (1) | CN1241907C (ko) |
| AT (1) | ATE349421T1 (ko) |
| AU (1) | AU2002316903B2 (ko) |
| BR (1) | BR0209828A (ko) |
| CA (1) | CA2447084A1 (ko) |
| CO (1) | CO5540291A2 (ko) |
| DE (1) | DE60217099T2 (ko) |
| MX (1) | MXPA03010404A (ko) |
| NZ (1) | NZ529368A (ko) |
| RU (1) | RU2284990C2 (ko) |
| WO (1) | WO2002092552A2 (ko) |
| ZA (1) | ZA200308592B (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1392281T3 (da) | 2000-12-20 | 2007-06-11 | Novartis Ag | Anti-endoparasitiske amidoacetonitriler |
| AR039020A1 (es) * | 2002-03-21 | 2005-02-02 | Novartis Ag | Compuestos de aminoacetonitrilo |
| GB0402677D0 (en) * | 2003-11-06 | 2004-03-10 | Novartis Ag | Organic compounds |
| ES2714578T3 (es) * | 2007-05-15 | 2019-05-29 | Merial Inc | Compuestos de ariloazol-2-il cianoetilamino, procedimiento de fabricación y procedimiento de utilización de los mismos |
| KR101782311B1 (ko) | 2008-10-21 | 2017-09-27 | 메리얼 인코포레이티드 | 티오아미드 화합물, 이의 제조 방법 및 사용 방법 |
| ME03409B (me) | 2008-11-14 | 2020-01-20 | Merial Inc | ENANTIOMERNO OBOGAĆENA PARAZITICIDALNA JEDINJENJA ARILOAZOL-2-il CIJANOETILAMINO |
| US8822689B2 (en) | 2012-09-19 | 2014-09-02 | Merial Limited | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873224A (en) * | 1988-05-23 | 1989-10-10 | Merck & Co., Inc. | Avermectin derivatives |
| NZ231773A (en) * | 1988-12-23 | 1992-09-25 | Merck & Co Inc | Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof |
| US6239077B1 (en) | 1998-05-01 | 2001-05-29 | Nihon Nohyaku Co., Ltd. | Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof |
| TWI261053B (en) * | 2001-12-06 | 2006-09-01 | Novartis Ag | Amidoacetonitrile compounds, their preparation, compositions and use as pesticides |
| TW200400932A (en) * | 2002-06-19 | 2004-01-16 | Novartis Ag | Organic compounds |
-
2002
- 2002-05-14 BR BR0209828-8A patent/BR0209828A/pt not_active IP Right Cessation
- 2002-05-14 US US10/477,289 patent/US7705044B2/en not_active Expired - Fee Related
- 2002-05-14 EP EP02745292A patent/EP1390344B1/en not_active Expired - Lifetime
- 2002-05-14 NZ NZ529368A patent/NZ529368A/en not_active IP Right Cessation
- 2002-05-14 KR KR1020037014727A patent/KR100628842B1/ko not_active IP Right Cessation
- 2002-05-14 AT AT02745292T patent/ATE349421T1/de not_active IP Right Cessation
- 2002-05-14 CA CA002447084A patent/CA2447084A1/en not_active Abandoned
- 2002-05-14 MX MXPA03010404A patent/MXPA03010404A/es unknown
- 2002-05-14 AU AU2002316903A patent/AU2002316903B2/en not_active Ceased
- 2002-05-14 JP JP2002589438A patent/JP4124661B2/ja not_active Expired - Fee Related
- 2002-05-14 CN CNB028119355A patent/CN1241907C/zh not_active Expired - Fee Related
- 2002-05-14 WO PCT/EP2002/005294 patent/WO2002092552A2/en active IP Right Grant
- 2002-05-14 DE DE60217099T patent/DE60217099T2/de not_active Expired - Lifetime
- 2002-05-14 RU RU2003134179/04A patent/RU2284990C2/ru not_active IP Right Cessation
-
2003
- 2003-11-04 ZA ZA200308592A patent/ZA200308592B/en unknown
- 2003-12-12 CO CO03108977A patent/CO5540291A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2003134179A (ru) | 2005-06-10 |
| RU2284990C2 (ru) | 2006-10-10 |
| JP2004533451A (ja) | 2004-11-04 |
| US20040220055A1 (en) | 2004-11-04 |
| CA2447084A1 (en) | 2002-11-21 |
| DE60217099T2 (de) | 2007-08-09 |
| BR0209828A (pt) | 2004-06-15 |
| CN1531525A (zh) | 2004-09-22 |
| ATE349421T1 (de) | 2007-01-15 |
| WO2002092552A3 (en) | 2003-12-11 |
| AU2002316903B2 (en) | 2006-01-12 |
| WO2002092552A2 (en) | 2002-11-21 |
| EP1390344A2 (en) | 2004-02-25 |
| JP4124661B2 (ja) | 2008-07-23 |
| MXPA03010404A (es) | 2004-03-09 |
| CN1241907C (zh) | 2006-02-15 |
| NZ529368A (en) | 2005-06-24 |
| KR100628842B1 (ko) | 2006-09-29 |
| KR20030094406A (ko) | 2003-12-11 |
| DE60217099D1 (de) | 2007-02-08 |
| CO5540291A2 (es) | 2005-07-29 |
| EP1390344B1 (en) | 2006-12-27 |
| US7705044B2 (en) | 2010-04-27 |
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