ZA200306283B - Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as IP antagonists. - Google Patents

Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as IP antagonists.

Info

Publication number
ZA200306283B
ZA200306283B ZA200306283A ZA200306283A ZA200306283B ZA 200306283 B ZA200306283 B ZA 200306283B ZA 200306283 A ZA200306283 A ZA 200306283A ZA 200306283 A ZA200306283 A ZA 200306283A ZA 200306283 B ZA200306283 B ZA 200306283B
Authority
ZA
South Africa
Prior art keywords
alkoxycarbonylamino
antagonists
carboxylic acid
acid derivatives
heteroaryl carboxylic
Prior art date
Application number
ZA200306283A
Other languages
English (en)
Inventor
Lopez-Tapia Francisco J Counde
Dov Nitzan
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA200306283B publication Critical patent/ZA200306283B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200306283A 2001-03-02 2003-08-13 Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as IP antagonists. ZA200306283B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27284901P 2001-03-02 2001-03-02

Publications (1)

Publication Number Publication Date
ZA200306283B true ZA200306283B (en) 2004-11-15

Family

ID=23041569

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200306283A ZA200306283B (en) 2001-03-02 2003-08-13 Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as IP antagonists.

Country Status (14)

Country Link
US (1) US6569860B2 (da)
EP (1) EP1368345B1 (da)
JP (1) JP2004526721A (da)
KR (1) KR100589990B1 (da)
CN (1) CN1280289C (da)
AR (1) AR033429A1 (da)
AT (1) ATE321041T1 (da)
BR (1) BR0207730A (da)
CA (1) CA2438813C (da)
DE (1) DE60210058T2 (da)
ES (1) ES2260425T3 (da)
MX (1) MXPA03007864A (da)
WO (1) WO2002070514A1 (da)
ZA (1) ZA200306283B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040054008A1 (en) * 2002-09-13 2004-03-18 Tohru Araki Medicament for treatment of nocturia
US20060171945A1 (en) * 2003-02-14 2006-08-03 Critchley Hilary Octavia D Ip receptor antagonists for the treatment of pathological uterine conditions
WO2007046646A1 (en) * 2005-10-20 2007-04-26 Lg Chem, Ltd. Novel organic silane compound
KR100822142B1 (ko) * 2005-10-20 2008-04-14 주식회사 엘지화학 신규한 유기 실란 화합물
AR069650A1 (es) * 2007-12-14 2010-02-10 Actelion Pharmaceuticals Ltd Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
US9295665B2 (en) 2013-03-12 2016-03-29 Allergan, Inc. Inhibition of neovascularization by simultaneous inhibition of prostanoid IP and EP4 receptors
US9321745B2 (en) * 2013-03-12 2016-04-26 Allergan, Inc. Inhibition of neovascularization by inhibition of prostanoid IP receptors
MA54133B1 (fr) 2018-03-08 2022-01-31 Incyte Corp Composés d'aminopyrazine diol utilisés comme inhibiteurs de pi3k-y
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
EP4119138A1 (en) * 2021-07-12 2023-01-18 Universität Hamburg Dhodh inhibitors and their use as antiviral agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908842A (en) 1995-12-08 1999-06-01 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
WO1999026925A1 (fr) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Inhibiteurs de tryptase comprenant des composants d'amide heterocycliques
ATE287875T1 (de) * 1998-10-06 2005-02-15 Dainippon Pharmaceutical Co 2,3-disubstituierte pyridinderivate, verfahren zur derren herstellung, sie enthaltende wirkstoffzubereitungen und zwischenprodukte für die herstellung
US6335459B1 (en) * 1998-12-23 2002-01-01 Syntex (U.S.A.) Llc Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators
PL353455A1 (en) * 1999-08-12 2003-11-17 Pharmacia Italia S.P.A. 3(5)-amino-pyrazole derivatives, process for their preparation and their use as antitumor agents
KR100523119B1 (ko) * 2000-03-16 2005-10-20 에프. 호프만-라 로슈 아게 Ip 길항제로서의 카복실산 유도체

Also Published As

Publication number Publication date
WO2002070514A1 (en) 2002-09-12
CA2438813A1 (en) 2002-09-12
CN1280289C (zh) 2006-10-18
CA2438813C (en) 2008-07-29
KR100589990B1 (ko) 2006-06-15
MXPA03007864A (es) 2003-12-04
CN1494544A (zh) 2004-05-05
JP2004526721A (ja) 2004-09-02
KR20030078962A (ko) 2003-10-08
DE60210058T2 (de) 2006-11-09
EP1368345B1 (en) 2006-03-22
US20020169171A1 (en) 2002-11-14
US6569860B2 (en) 2003-05-27
ATE321041T1 (de) 2006-04-15
ES2260425T3 (es) 2006-11-01
AR033429A1 (es) 2003-12-17
BR0207730A (pt) 2004-03-23
DE60210058D1 (de) 2006-05-11
EP1368345A1 (en) 2003-12-10

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