ZA200304635B - Hypoallergenic and non-irritant skin care formulations. - Google Patents
Hypoallergenic and non-irritant skin care formulations. Download PDFInfo
- Publication number
- ZA200304635B ZA200304635B ZA200304635A ZA200304635A ZA200304635B ZA 200304635 B ZA200304635 B ZA 200304635B ZA 200304635 A ZA200304635 A ZA 200304635A ZA 200304635 A ZA200304635 A ZA 200304635A ZA 200304635 B ZA200304635 B ZA 200304635B
- Authority
- ZA
- South Africa
- Prior art keywords
- skin care
- care formulation
- oil phase
- skin
- formulation according
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 76
- 238000009472 formulation Methods 0.000 title claims description 72
- 239000002085 irritant Substances 0.000 title claims description 21
- 231100000021 irritant Toxicity 0.000 title claims description 21
- 230000000774 hypoallergenic effect Effects 0.000 title claims description 15
- 239000004615 ingredient Substances 0.000 claims description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 15
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 14
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- 230000037307 sensitive skin Effects 0.000 claims description 9
- 238000002560 therapeutic procedure Methods 0.000 claims description 8
- 235000011187 glycerol Nutrition 0.000 claims description 7
- 239000004310 lactic acid Substances 0.000 claims description 7
- 235000014655 lactic acid Nutrition 0.000 claims description 7
- 235000019271 petrolatum Nutrition 0.000 claims description 7
- 238000011282 treatment Methods 0.000 claims description 7
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims description 6
- 229940100524 ethylhexylglycerin Drugs 0.000 claims description 6
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 6
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 239000008213 purified water Substances 0.000 claims description 6
- 229930003231 vitamin Chemical class 0.000 claims description 6
- 239000011782 vitamin Chemical class 0.000 claims description 6
- 229940088594 vitamin Drugs 0.000 claims description 6
- 235000013343 vitamin Nutrition 0.000 claims description 6
- NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 claims description 5
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims description 5
- 239000004264 Petrolatum Substances 0.000 claims description 5
- 235000019388 lanolin Nutrition 0.000 claims description 5
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 5
- 229940066842 petrolatum Drugs 0.000 claims description 5
- 229940048845 polyglyceryl-3 diisostearate Drugs 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 239000001540 sodium lactate Substances 0.000 claims description 5
- 229940005581 sodium lactate Drugs 0.000 claims description 5
- 235000011088 sodium lactate Nutrition 0.000 claims description 5
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 5
- 239000004166 Lanolin Substances 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 239000004202 carbamide Substances 0.000 claims description 4
- 239000007765 cera alba Substances 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 4
- 239000007762 w/o emulsion Substances 0.000 claims description 4
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 238000004040 coloring Methods 0.000 claims description 3
- -1 colorings Substances 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 229940039717 lanolin Drugs 0.000 claims description 3
- 239000000419 plant extract Substances 0.000 claims description 3
- 238000011321 prophylaxis Methods 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 230000001185 psoriatic effect Effects 0.000 claims description 3
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000000475 sunscreen effect Effects 0.000 claims description 2
- 239000000516 sunscreening agent Substances 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims 6
- 238000001816 cooling Methods 0.000 claims 4
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 claims 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 2
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 229930003448 Vitamin K Natural products 0.000 claims 1
- 239000003470 adrenal cortex hormone Substances 0.000 claims 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 1
- 230000001857 anti-mycotic effect Effects 0.000 claims 1
- 239000002543 antimycotic Substances 0.000 claims 1
- 150000001277 beta hydroxy acids Chemical class 0.000 claims 1
- LWQQLNNNIPYSNX-UROSTWAQSA-N calcipotriol Chemical compound C1([C@H](O)/C=C/[C@@H](C)[C@@H]2[C@]3(CCCC(/[C@@H]3CC2)=C\C=C\2C([C@@H](O)C[C@H](O)C/2)=C)C)CC1 LWQQLNNNIPYSNX-UROSTWAQSA-N 0.000 claims 1
- 229960002882 calcipotriol Drugs 0.000 claims 1
- RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical compound C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 claims 1
- 238000007599 discharging Methods 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 229960004488 linolenic acid Drugs 0.000 claims 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 229960004889 salicylic acid Drugs 0.000 claims 1
- BJYLYJCXYAMOFT-RSFVBTMBSA-N tacalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CC[C@@H](O)C(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C BJYLYJCXYAMOFT-RSFVBTMBSA-N 0.000 claims 1
- 229960004907 tacalcitol Drugs 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 235000019168 vitamin K Nutrition 0.000 claims 1
- 239000011712 vitamin K Substances 0.000 claims 1
- 150000003721 vitamin K derivatives Chemical class 0.000 claims 1
- 229940046010 vitamin k Drugs 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 45
- 206010013786 Dry skin Diseases 0.000 description 9
- 230000037336 dry skin Effects 0.000 description 9
- 210000000434 stratum corneum Anatomy 0.000 description 8
- 230000002009 allergenic effect Effects 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 201000004681 Psoriasis Diseases 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000002349 favourable effect Effects 0.000 description 5
- 239000004909 Moisturizer Substances 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000002906 microbiologic effect Effects 0.000 description 4
- 230000001333 moisturizer Effects 0.000 description 4
- 239000007764 o/w emulsion Substances 0.000 description 4
- 239000002304 perfume Substances 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- 206010012442 Dermatitis contact Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000013566 allergen Substances 0.000 description 2
- 208000002029 allergic contact dermatitis Diseases 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000003974 emollient agent Substances 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 206010021198 ichthyosis Diseases 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- XRMDCWJNPDVAFI-UHFFFAOYSA-N 2,2,6,6-tetramethyl-1-oxopiperidin-1-ium-4-ol Chemical compound CC1(C)CC(O)CC(C)(C)[N+]1=O XRMDCWJNPDVAFI-UHFFFAOYSA-N 0.000 description 1
- KVZLHPXEUGJPAH-UHFFFAOYSA-N 2-oxidanylpropanoic acid Chemical compound CC(O)C(O)=O.CC(O)C(O)=O KVZLHPXEUGJPAH-UHFFFAOYSA-N 0.000 description 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000011360 adjunctive therapy Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- 150000001783 ceramides Chemical class 0.000 description 1
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 1
- 229940073507 cocamidopropyl betaine Drugs 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 230000009097 homeostatic mechanism Effects 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 229940099367 lanolin alcohols Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 208000002440 photoallergic dermatitis Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000036620 skin dryness Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00127555A EP1214930B1 (de) | 2000-12-15 | 2000-12-15 | Hypoallergenes nichtreizendes Hautpflegemittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200304635B true ZA200304635B (en) | 2004-02-17 |
Family
ID=8170678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200304635A ZA200304635B (en) | 2000-12-15 | 2003-06-13 | Hypoallergenic and non-irritant skin care formulations. |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1214930B1 (de) |
| JP (1) | JP4398641B2 (de) |
| AT (2) | ATE262887T1 (de) |
| AU (2) | AU3458102A (de) |
| BR (1) | BRPI0116215B8 (de) |
| CA (1) | CA2433177C (de) |
| DE (2) | DE60009521T2 (de) |
| DK (1) | DK1214930T3 (de) |
| ES (2) | ES2218055T3 (de) |
| HU (1) | HU230039B1 (de) |
| MX (1) | MXPA03005330A (de) |
| NZ (1) | NZ526343A (de) |
| PT (2) | PT1214930E (de) |
| TR (1) | TR200401156T4 (de) |
| WO (1) | WO2002047642A1 (de) |
| ZA (1) | ZA200304635B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7595378B2 (en) | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
| US7959935B2 (en) | 2002-05-03 | 2011-06-14 | Children's Hospital Medical Center | Simulated vernix compositions for skin cleansing and other applications |
| CA2595023A1 (en) * | 2005-01-19 | 2006-07-27 | Children's Hospital Medical Center | Simulated vernix compositions for skin cleansing and other applications |
| DE602006019074D1 (de) | 2005-04-15 | 2011-02-03 | Einstein Coll Med | Vitamin k zur vorbeugung und behandlung von hautausschlag infolge einer anti-egfr-therapie |
| FR2885491B1 (fr) * | 2005-05-16 | 2020-03-06 | Nutricos Technologies | Traitement de la secheresse keratinique par des glycerides |
| WO2007132439A1 (en) * | 2006-05-14 | 2007-11-22 | Hlavin Industries Ltd. | Long acting deodorant composition |
| EP2043685B1 (de) | 2006-07-03 | 2015-12-23 | Genmab A/S | Prävention von hautausschlag bei patienten in anti-egfr-therapie |
| US7758901B2 (en) | 2007-02-16 | 2010-07-20 | Betty Bellman | Compositions and methods for alleviating skin disorders |
| US9011943B2 (en) | 2007-02-16 | 2015-04-21 | Skin Evolution LLC | Compositions and methods for alleviating skin disorders |
| WO2008101239A1 (en) * | 2007-02-16 | 2008-08-21 | Betty Bellman | Compositions and methods for alleviating skin disorders |
| US7488500B2 (en) | 2007-02-16 | 2009-02-10 | Betty Bellman | Compositions and methods for alleviating skin disorders |
| FR2917609B1 (fr) * | 2007-06-22 | 2012-11-16 | Oreal | Composition de maquillage comprenant un compose hydroxyle. |
| US8815953B2 (en) | 2008-03-13 | 2014-08-26 | Spectrum Pharmaceuticals, Inc. | Formulations of vitamin K analogs for topical use |
| DE102010063585A1 (de) * | 2010-12-20 | 2012-06-21 | Henkel Ag & Co. Kgaa | W/O-Emulsionen |
| JP7281261B2 (ja) * | 2018-09-20 | 2023-05-25 | 花王株式会社 | 物質の感覚刺激性の解析方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19651478A1 (de) * | 1996-12-11 | 1998-06-18 | Beiersdorf Ag | Lichtschutzzubereitungen mit einem Gehalt an oberflächenaktiven Mono- bzw. Oligoglycerylverbindungen, wasselöslichen UV-Filtersubstanzen und ggf. anorganischen Mikropigmenten |
| DE19843876A1 (de) * | 1998-09-25 | 2000-04-13 | Cognis Deutschland Gmbh | Selbstemulgierende W/O-Emulsionsgrundlagen |
-
2000
- 2000-12-15 TR TR2004/01156T patent/TR200401156T4/xx unknown
- 2000-12-15 AT AT00127555T patent/ATE262887T1/de active
- 2000-12-15 ES ES00127555T patent/ES2218055T3/es not_active Expired - Lifetime
- 2000-12-15 PT PT00127555T patent/PT1214930E/pt unknown
- 2000-12-15 DK DK00127555T patent/DK1214930T3/da active
- 2000-12-15 DE DE60009521T patent/DE60009521T2/de not_active Expired - Lifetime
- 2000-12-15 EP EP00127555A patent/EP1214930B1/de not_active Expired - Lifetime
-
2001
- 2001-12-14 DE DE60133038T patent/DE60133038T2/de not_active Expired - Lifetime
- 2001-12-14 MX MXPA03005330A patent/MXPA03005330A/es active IP Right Grant
- 2001-12-14 AU AU3458102A patent/AU3458102A/xx active Pending
- 2001-12-14 AT AT01985412T patent/ATE387180T1/de not_active IP Right Cessation
- 2001-12-14 NZ NZ526343A patent/NZ526343A/en not_active IP Right Cessation
- 2001-12-14 ES ES01985412T patent/ES2302756T3/es not_active Expired - Lifetime
- 2001-12-14 AU AU2002234581A patent/AU2002234581B2/en not_active Ceased
- 2001-12-14 WO PCT/EP2001/014825 patent/WO2002047642A1/en active IP Right Grant
- 2001-12-14 JP JP2002549217A patent/JP4398641B2/ja not_active Expired - Fee Related
- 2001-12-14 BR BRPI0116215A patent/BRPI0116215B8/pt not_active IP Right Cessation
- 2001-12-14 EP EP01985412A patent/EP1343469B1/de not_active Expired - Lifetime
- 2001-12-14 PT PT01985412T patent/PT1343469E/pt unknown
- 2001-12-14 HU HU0302155A patent/HU230039B1/hu not_active IP Right Cessation
- 2001-12-14 CA CA002433177A patent/CA2433177C/en not_active Expired - Fee Related
-
2003
- 2003-06-13 ZA ZA200304635A patent/ZA200304635B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2218055T3 (es) | 2004-11-16 |
| MXPA03005330A (es) | 2004-12-03 |
| ES2302756T3 (es) | 2008-08-01 |
| EP1343469B1 (de) | 2008-02-27 |
| EP1214930A1 (de) | 2002-06-19 |
| EP1343469A1 (de) | 2003-09-17 |
| ATE387180T1 (de) | 2008-03-15 |
| ATE262887T1 (de) | 2004-04-15 |
| WO2002047642A1 (en) | 2002-06-20 |
| DE60133038T2 (de) | 2009-02-26 |
| AU3458102A (en) | 2002-06-24 |
| PT1343469E (pt) | 2008-06-04 |
| HUP0302155A3 (en) | 2012-09-28 |
| DE60133038D1 (de) | 2008-04-10 |
| PT1214930E (pt) | 2004-08-31 |
| CA2433177C (en) | 2007-07-03 |
| TR200401156T4 (tr) | 2004-07-21 |
| NZ526343A (en) | 2003-10-31 |
| HUP0302155A2 (hu) | 2003-09-29 |
| BR0116215A (pt) | 2004-08-17 |
| CA2433177A1 (en) | 2002-06-20 |
| EP1214930B1 (de) | 2004-03-31 |
| JP2004515521A (ja) | 2004-05-27 |
| DK1214930T3 (da) | 2004-07-26 |
| DE60009521T2 (de) | 2005-03-03 |
| DE60009521D1 (de) | 2004-05-06 |
| JP4398641B2 (ja) | 2010-01-13 |
| AU2002234581B2 (en) | 2004-09-23 |
| BRPI0116215B1 (pt) | 2015-06-02 |
| BRPI0116215B8 (pt) | 2021-05-25 |
| HU230039B1 (hu) | 2015-05-28 |
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