ZA200304557B - Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. - Google Patents
Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. Download PDFInfo
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- ZA200304557B ZA200304557B ZA200304557A ZA200304557A ZA200304557B ZA 200304557 B ZA200304557 B ZA 200304557B ZA 200304557 A ZA200304557 A ZA 200304557A ZA 200304557 A ZA200304557 A ZA 200304557A ZA 200304557 B ZA200304557 B ZA 200304557B
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Classifications
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00128329 | 2000-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200304557B true ZA200304557B (en) | 2004-09-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200304557A ZA200304557B (en) | 2000-12-22 | 2003-06-11 | Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. |
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|---|---|
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| EP (1) | EP1345609B1 (enExample) |
| JP (1) | JP4077319B2 (enExample) |
| KR (1) | KR100545906B1 (enExample) |
| CN (1) | CN1260226C (enExample) |
| AR (1) | AR032379A1 (enExample) |
| AT (1) | ATE297734T1 (enExample) |
| AU (1) | AU2002216095B2 (enExample) |
| BR (1) | BR0116378A (enExample) |
| CA (1) | CA2432077C (enExample) |
| DE (1) | DE60111568T2 (enExample) |
| DK (1) | DK1345609T3 (enExample) |
| ES (1) | ES2243400T3 (enExample) |
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| PT (1) | PT1345609E (enExample) |
| WO (1) | WO2002051418A1 (enExample) |
| ZA (1) | ZA200304557B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275096A3 (en) | 2005-08-26 | 2011-07-13 | Braincells, Inc. | Neurogenesis via modulation of the muscarinic receptors |
| WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| EP2314289A1 (en) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| EP1981337B1 (en) * | 2006-01-19 | 2015-09-02 | Athersys, Inc. | Thiophenyl azepines as serotonin 5-ht2c receptor ligands and uses thereof |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| WO2008030651A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| KR101100864B1 (ko) * | 2009-06-12 | 2012-01-02 | 양준호 | 자동차 광택기용 광택패드 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3136654A1 (de) | 1981-09-16 | 1983-03-31 | Zahnradfabrik Friedrichshafen Ag, 7990 Friedrichshafen | Linearverschieblicher arbeitsarm, insbesondere fuer handhabungsgeraete |
| WO1999044639A1 (en) * | 1998-03-03 | 1999-09-10 | Yamanouchi Pharmaceutical Co., Ltd. | Remedies for brain infarction |
| ID29095A (id) * | 1998-10-02 | 2001-07-26 | Novartis Ag Cs | Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan |
| GB9823847D0 (en) * | 1998-11-02 | 1998-12-23 | Lilly Co Eli | Pharmaceutical compounds |
| ES2209728T3 (es) * | 1999-08-06 | 2004-07-01 | F. Hoffmann-La Roche Ag | Tetrahidro-benzo(d)azepinas y su uso como antagonistas de receptores de glutamato metabotropico. |
| EP1074549B1 (en) * | 1999-08-06 | 2003-11-19 | F. Hoffmann-La Roche Ag | Tetrahydro-benzo(d)azepines and their use as antagonists at metabotropic glutamate receptors |
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2001
- 2001-12-11 AT AT01271999T patent/ATE297734T1/de active
- 2001-12-11 BR BR0116378-7A patent/BR0116378A/pt not_active IP Right Cessation
- 2001-12-11 EP EP01271999A patent/EP1345609B1/en not_active Expired - Lifetime
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- 2001-12-11 MX MXPA03005515A patent/MXPA03005515A/es active IP Right Grant
- 2001-12-11 DK DK01271999T patent/DK1345609T3/da active
- 2001-12-11 DE DE60111568T patent/DE60111568T2/de not_active Expired - Lifetime
- 2001-12-11 PT PT01271999T patent/PT1345609E/pt unknown
- 2001-12-11 ES ES01271999T patent/ES2243400T3/es not_active Expired - Lifetime
- 2001-12-11 CA CA2432077A patent/CA2432077C/en not_active Expired - Fee Related
- 2001-12-11 WO PCT/EP2001/014527 patent/WO2002051418A1/en not_active Ceased
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- 2001-12-20 AR ARP010105926A patent/AR032379A1/es unknown
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2003
- 2003-06-11 ZA ZA200304557A patent/ZA200304557B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1345609E (pt) | 2005-08-31 |
| ES2243400T3 (es) | 2005-12-01 |
| CN1487831A (zh) | 2004-04-07 |
| EP1345609B1 (en) | 2005-06-15 |
| US6586422B2 (en) | 2003-07-01 |
| CA2432077C (en) | 2011-01-18 |
| CN1260226C (zh) | 2006-06-21 |
| MXPA03005515A (es) | 2003-09-25 |
| JP4077319B2 (ja) | 2008-04-16 |
| AR032379A1 (es) | 2003-11-05 |
| US20020123488A1 (en) | 2002-09-05 |
| KR100545906B1 (ko) | 2006-01-26 |
| CA2432077A1 (en) | 2002-07-04 |
| ATE297734T1 (de) | 2005-07-15 |
| KR20030062444A (ko) | 2003-07-25 |
| WO2002051418A1 (en) | 2002-07-04 |
| BR0116378A (pt) | 2003-10-28 |
| DE60111568T2 (de) | 2006-05-11 |
| DE60111568D1 (de) | 2005-07-21 |
| DK1345609T3 (da) | 2005-10-03 |
| EP1345609A1 (en) | 2003-09-24 |
| JP2004517850A (ja) | 2004-06-17 |
| AU2002216095B2 (en) | 2005-12-01 |
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