ZA200303223B - Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation. - Google Patents
Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation.Info
- Publication number
- ZA200303223B ZA200303223B ZA200303223A ZA200303223A ZA200303223B ZA 200303223 B ZA200303223 B ZA 200303223B ZA 200303223 A ZA200303223 A ZA 200303223A ZA 200303223 A ZA200303223 A ZA 200303223A ZA 200303223 B ZA200303223 B ZA 200303223B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiazolidine
- pyridyl
- ethoxy
- benzyl
- amino
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN805CH2000 | 2000-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200303223B true ZA200303223B (en) | 2004-07-26 |
Family
ID=29266775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200303223A ZA200303223B (en) | 2000-09-26 | 2003-04-24 | Novel polymorphic forms of 5-[4-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1322647A1 (xx) |
JP (1) | JP2004509961A (xx) |
AU (1) | AU9123201A (xx) |
BR (1) | BR0114196A (xx) |
CA (1) | CA2426117A1 (xx) |
CZ (1) | CZ2003864A3 (xx) |
HU (1) | HUP0301161A3 (xx) |
IL (1) | IL155036A0 (xx) |
MX (1) | MXPA03002580A (xx) |
NO (1) | NO324968B1 (xx) |
NZ (1) | NZ525498A (xx) |
PL (1) | PL360661A1 (xx) |
SK (1) | SK3752003A3 (xx) |
WO (1) | WO2002026737A1 (xx) |
ZA (1) | ZA200303223B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020137940A1 (en) | 1997-12-16 | 2002-09-26 | Smithkline Beecham P.L.C. | 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical |
GB9726563D0 (en) | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
US6664278B2 (en) | 1997-12-16 | 2003-12-16 | Smithkline Beecham P.L.C. | Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt |
BR0009934A (pt) | 1999-04-23 | 2002-06-04 | Smithkline Beecham Plc | Produto farmacêutico |
US20040248945A1 (en) | 1999-04-23 | 2004-12-09 | Smithkline Beecham P.L.C. | Thiazolidinedione derivative and its use as antidiabetic |
PE20010044A1 (es) | 1999-04-23 | 2001-03-10 | Smithkline Beecham Plc | Polimorfo de sal del acido maleico de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]-tiazolidina-2,4-diona |
WO2004062667A1 (en) * | 2003-01-08 | 2004-07-29 | Dr. Reddy's Laboratories Limited | Amorphous form of rosiglitazone maleate and process for preparation thereof |
GB0307259D0 (en) * | 2003-03-28 | 2003-05-07 | Glaxo Group Ltd | Process |
EP1468997A3 (en) * | 2003-04-18 | 2004-11-03 | CHEMI S.p.A. | Polymorphous forms of rosiglitazone maleate |
GB2405403A (en) | 2003-08-29 | 2005-03-02 | Cipla Ltd | Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base |
UA83504C2 (xx) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Поліморфні форми 3-(4-аміно-1-оксо-1,3-дигідроізоіндол-2-іл)піперидин-2,6-діону$полиморфные формы 3-(4-амино-1-оксо-1,3-дигидроизоиндол-2-ил) пиперидин-2,6-диона |
AR047541A1 (es) * | 2004-02-13 | 2006-01-25 | Sandoz Ag | Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas |
US20070225337A1 (en) * | 2004-03-31 | 2007-09-27 | Sandoz Ag | Novel Co-Precipitate of Amorphous Rosiglitazone |
WO2005108396A1 (ja) * | 2004-05-11 | 2005-11-17 | Santen Pharmaceutical Co., Ltd. | 角結膜障害治療剤 |
JP2005350451A (ja) * | 2004-05-11 | 2005-12-22 | Santen Pharmaceut Co Ltd | 角結膜障害治療剤 |
CZ2004844A3 (cs) * | 2004-07-27 | 2006-03-15 | Zentiva, A. S | Sul kyseliny stavelové s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionu azpusob její prípravy a její pouzití |
ITMI20041537A1 (it) * | 2004-07-28 | 2004-10-28 | Chemi Spa | Nuova forma polimorfa del rosiglitazone maleato |
CZ298424B6 (cs) * | 2005-05-24 | 2007-09-26 | Zentiva, A. S. | Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel |
EP2184055A1 (en) | 2008-11-07 | 2010-05-12 | LEK Pharmaceuticals d.d. | Process for preparing solid dosage forms of rosiglitazone maleate |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
JP2000511875A (ja) * | 1996-06-19 | 2000-09-12 | ドクター・レディーズ・リサーチ・ファウンデーション | 抗糖尿病活性を増強されたトログリタゾンの新規な多形型及びそれらの製造方法 |
CN1221417A (zh) * | 1996-07-26 | 1999-06-30 | 雷迪博士研究基金会 | 具有抗糖尿病、降低血脂、抗高血压性能的噻唑烷二酮化合物,其制备方法及其药物组合物 |
GB9726566D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
PE20010044A1 (es) * | 1999-04-23 | 2001-03-10 | Smithkline Beecham Plc | Polimorfo de sal del acido maleico de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]-tiazolidina-2,4-diona |
BR0009934A (pt) * | 1999-04-23 | 2002-06-04 | Smithkline Beecham Plc | Produto farmacêutico |
-
2001
- 2001-09-25 IL IL15503601A patent/IL155036A0/xx unknown
- 2001-09-25 CA CA002426117A patent/CA2426117A1/en not_active Abandoned
- 2001-09-25 JP JP2002531121A patent/JP2004509961A/ja active Pending
- 2001-09-25 BR BR0114196-1A patent/BR0114196A/pt not_active Application Discontinuation
- 2001-09-25 WO PCT/US2001/029896 patent/WO2002026737A1/en active IP Right Grant
- 2001-09-25 PL PL01360661A patent/PL360661A1/xx not_active Application Discontinuation
- 2001-09-25 HU HU0301161A patent/HUP0301161A3/hu unknown
- 2001-09-25 CZ CZ2003864A patent/CZ2003864A3/cs unknown
- 2001-09-25 EP EP01971336A patent/EP1322647A1/en not_active Withdrawn
- 2001-09-25 SK SK375-2003A patent/SK3752003A3/sk not_active Application Discontinuation
- 2001-09-25 MX MXPA03002580A patent/MXPA03002580A/es active IP Right Grant
- 2001-09-25 AU AU9123201A patent/AU9123201A/xx active Pending
- 2001-09-25 NZ NZ525498A patent/NZ525498A/en unknown
-
2003
- 2003-03-25 NO NO20031356A patent/NO324968B1/no unknown
- 2003-04-24 ZA ZA200303223A patent/ZA200303223B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PL360661A1 (en) | 2004-09-20 |
EP1322647A1 (en) | 2003-07-02 |
CZ2003864A3 (cs) | 2004-01-14 |
NO20031356D0 (no) | 2003-03-25 |
BR0114196A (pt) | 2003-07-22 |
MXPA03002580A (es) | 2003-10-15 |
CA2426117A1 (en) | 2002-04-04 |
HUP0301161A3 (en) | 2005-04-28 |
WO2002026737A1 (en) | 2002-04-04 |
IL155036A0 (en) | 2003-10-31 |
AU9123201A (en) | 2002-04-08 |
NO20031356L (no) | 2003-05-26 |
NO324968B1 (no) | 2008-01-14 |
NZ525498A (en) | 2004-11-26 |
HUP0301161A2 (hu) | 2003-11-28 |
JP2004509961A (ja) | 2004-04-02 |
WO2002026737A8 (en) | 2003-11-06 |
SK3752003A3 (sk) | 2005-03-04 |
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