ZA200301078B - 7-oxo pyridopyrimidines. - Google Patents
7-oxo pyridopyrimidines.Info
- Publication number
- ZA200301078B ZA200301078B ZA200301078A ZA200301078A ZA200301078B ZA 200301078 B ZA200301078 B ZA 200301078B ZA 200301078 A ZA200301078 A ZA 200301078A ZA 200301078 A ZA200301078 A ZA 200301078A ZA 200301078 B ZA200301078 B ZA 200301078B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridopyrimidines
- oxo
- oxo pyridopyrimidines
- Prior art date
Links
- UWABAWGNHPXGBQ-UHFFFAOYSA-N 6h-pyrido[3,2-d]pyrimidin-7-one Chemical class C1=NC=NC2=CC(=O)CN=C21 UWABAWGNHPXGBQ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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-
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22957700P | 2000-08-31 | 2000-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200301078B true ZA200301078B (en) | 2004-05-07 |
Family
ID=22861834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200301078A ZA200301078B (en) | 2000-08-31 | 2003-02-07 | 7-oxo pyridopyrimidines. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1315727B1 (OSRAM) |
| JP (1) | JP4146721B2 (OSRAM) |
| KR (1) | KR100582325B1 (OSRAM) |
| CN (2) | CN100358892C (OSRAM) |
| AR (1) | AR033996A1 (OSRAM) |
| AT (1) | ATE298751T1 (OSRAM) |
| AU (2) | AU2002212147B2 (OSRAM) |
| BR (1) | BR0113590A (OSRAM) |
| CA (1) | CA2420122A1 (OSRAM) |
| DE (1) | DE60111752T2 (OSRAM) |
| ES (1) | ES2243568T3 (OSRAM) |
| GT (1) | GT200100190A (OSRAM) |
| MX (1) | MXPA03001733A (OSRAM) |
| PA (1) | PA8527401A1 (OSRAM) |
| PE (1) | PE20020524A1 (OSRAM) |
| UY (1) | UY26920A1 (OSRAM) |
| WO (1) | WO2002018379A2 (OSRAM) |
| ZA (1) | ZA200301078B (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2004133811A (ru) * | 2002-04-19 | 2005-04-20 | Смитклайн Бичам Корпорейшн (US) | Новые соединения |
| WO2004060346A2 (en) | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| ATE451115T1 (de) * | 2003-07-07 | 2009-12-15 | Van Andel Res Inst | Hemmung der tumor-angiogenese durch eine kombination von thrombospondin-1 und hemmern des vaskulären endothel-wachstumsfaktors |
| WO2005105097A2 (en) * | 2004-04-28 | 2005-11-10 | Gpc Biotech Ag | Pyridopyrimidines for treating inflammatory and other diseases |
| AU2005254800B2 (en) * | 2004-06-15 | 2010-12-09 | Pfizer Inc. | Benzimidazolone carboxylic acid derivatives |
| US20090306380A1 (en) * | 2005-04-25 | 2009-12-10 | Shigeyoshi Nishino | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde |
| JP2006321749A (ja) * | 2005-05-19 | 2006-11-30 | Ube Ind Ltd | ２−シアノマロンアルデヒドのアルカリ金属塩の製法 |
| ATE439361T1 (de) | 2006-01-31 | 2009-08-15 | Hoffmann La Roche | 7h-pyridoä3,4-düpyrimidin-8-one, ihre herstellung und ihre verwendung als proteinkinaseinhibitoren |
| EP2094698A1 (en) | 2006-11-09 | 2009-09-02 | F. Hoffmann-Roche AG | Substituted 6-phenyl-pyrido [2,3-d]pyrimidin-7-one derivatives as kinase inhibitors and methods for using the same |
| JP2010529973A (ja) | 2007-06-15 | 2010-09-02 | エフ．ホフマン−ラ ロシュ アーゲー | ３−アミノ−ペンタン−１，５−ジオールの新規製造方法 |
| EP2486037A4 (en) * | 2009-10-09 | 2013-01-16 | Afraxis Inc | 8-ETHYL-6- (ARYL) PYRIDO [2,3-D] PYRIMIDIN-7 (8H) -ONES FOR THE TREATMENT OF CNS DISORDERS |
| US20120184542A1 (en) | 2011-01-19 | 2012-07-19 | Kevin Anderson | Pyrido pyrimidines |
| JP6101341B2 (ja) * | 2012-03-22 | 2017-03-22 | オスコテック, インコーポレーテッドOscotec, Inc. | 置換ピリドピリミジン化合物およびｆｌｔ３阻害剤としてのこれらの使用 |
| NZ711376A (en) | 2013-03-15 | 2020-01-31 | Sanofi Sa | Heteroaryl compounds and uses thereof |
| AR095464A1 (es) | 2013-03-15 | 2015-10-21 | Celgene Avilomics Res Inc | Compuestos de heteroarilo y usos de los mismos |
| EA036160B1 (ru) | 2013-03-15 | 2020-10-08 | Селджен Кар Ллс | Гетероарильные соединения и их применение |
| DK3691620T3 (da) | 2017-10-05 | 2022-10-03 | Fulcrum Therapeutics Inc | P38-kinaseinhibitor reducerer dux4- og downstream-gen-ekspression til behandling af fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| MX2020013757A (es) * | 2018-09-14 | 2021-03-02 | Abbisko Therapeutics Co Ltd | Inhibidor del fgfr, metodo de preparacion y aplicacion del mismo. |
| CN115960098A (zh) * | 2020-09-11 | 2023-04-14 | 上海凌达生物医药有限公司 | 一类含氮稠环类化合物的制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6183168A (ja) * | 1984-09-28 | 1986-04-26 | Ube Ind Ltd | ２−メルカプト−４−アミノ−５−ホルミルピリミジンおよびその製法 |
| IL117923A (en) * | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| WO1997044321A1 (en) * | 1996-05-20 | 1997-11-27 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| US5945422A (en) * | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| CA2420286A1 (en) * | 2000-08-31 | 2002-03-07 | F. Hoffmann-La Roche Ag | 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation |
-
2001
- 2001-08-22 MX MXPA03001733A patent/MXPA03001733A/es active IP Right Grant
- 2001-08-22 CN CNB018150276A patent/CN100358892C/zh not_active Expired - Fee Related
- 2001-08-22 DE DE60111752T patent/DE60111752T2/de not_active Expired - Fee Related
- 2001-08-22 ES ES01980258T patent/ES2243568T3/es not_active Expired - Lifetime
- 2001-08-22 AT AT01980258T patent/ATE298751T1/de not_active IP Right Cessation
- 2001-08-22 WO PCT/EP2001/009688 patent/WO2002018379A2/en not_active Ceased
- 2001-08-22 AU AU2002212147A patent/AU2002212147B2/en not_active Ceased
- 2001-08-22 BR BR0113590-2A patent/BR0113590A/pt not_active Application Discontinuation
- 2001-08-22 JP JP2002523894A patent/JP4146721B2/ja not_active Expired - Fee Related
- 2001-08-22 KR KR1020037002955A patent/KR100582325B1/ko not_active Expired - Fee Related
- 2001-08-22 CA CA002420122A patent/CA2420122A1/en not_active Abandoned
- 2001-08-22 AU AU1214702A patent/AU1214702A/xx active Pending
- 2001-08-22 EP EP01980258A patent/EP1315727B1/en not_active Expired - Lifetime
- 2001-08-22 CN CNB2005100835295A patent/CN1303072C/zh not_active Expired - Fee Related
- 2001-08-28 PA PA20018527401A patent/PA8527401A1/es unknown
- 2001-08-28 PE PE2001000861A patent/PE20020524A1/es not_active Application Discontinuation
- 2001-08-30 AR ARP010104131A patent/AR033996A1/es unknown
- 2001-08-30 UY UY26920A patent/UY26920A1/es not_active Application Discontinuation
- 2001-09-18 GT GT200100190A patent/GT200100190A/es unknown
-
2003
- 2003-02-07 ZA ZA200301078A patent/ZA200301078B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1721412A (zh) | 2006-01-18 |
| ES2243568T3 (es) | 2005-12-01 |
| WO2002018379A3 (en) | 2002-07-25 |
| CN1303072C (zh) | 2007-03-07 |
| UY26920A1 (es) | 2002-02-28 |
| ATE298751T1 (de) | 2005-07-15 |
| AU2002212147B2 (en) | 2007-10-18 |
| GT200100190A (es) | 2002-05-23 |
| PA8527401A1 (es) | 2002-07-30 |
| BR0113590A (pt) | 2003-07-22 |
| CN100358892C (zh) | 2008-01-02 |
| JP4146721B2 (ja) | 2008-09-10 |
| KR100582325B1 (ko) | 2006-05-22 |
| PE20020524A1 (es) | 2002-06-18 |
| AU1214702A (en) | 2002-03-13 |
| KR20030022423A (ko) | 2003-03-15 |
| CA2420122A1 (en) | 2002-03-07 |
| JP2004507540A (ja) | 2004-03-11 |
| DE60111752T2 (de) | 2006-05-04 |
| CN1451004A (zh) | 2003-10-22 |
| MXPA03001733A (es) | 2003-05-27 |
| AR033996A1 (es) | 2004-01-21 |
| EP1315727B1 (en) | 2005-06-29 |
| DE60111752D1 (de) | 2005-08-04 |
| WO2002018379A2 (en) | 2002-03-07 |
| EP1315727A2 (en) | 2003-06-04 |
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| ZA200205482B (en) | Aminosulfonylbiphenyl derivatives. | |
| MXPA03005494A (es) | Benzoilpiridazinas. | |
| ZA200206150B (en) | Aminomethyl-phenyl-cyclohexanone derivatives. | |
| MXPA03002521A (es) | Triazol-epotilona. | |
| GB0006787D0 (en) | The ecotruck | |
| GB0024248D0 (en) | The unibroom | |
| GB0028055D0 (en) | The conegro | |
| GB0024885D0 (en) | The space-finder | |
| ZA200302241B (en) | Triazolo-epothilones. | |
| TJ414B (en) | Thermoresistor. | |
| ZA200103473B (en) | Headware. | |
| GB0017697D0 (en) | The lift buddy | |
| GB0000021D0 (en) | Plug i.d |