ZA200300085B - 7-hydroxyepiandrosterone having neuroprotective activity. - Google Patents
7-hydroxyepiandrosterone having neuroprotective activity. Download PDFInfo
- Publication number
- ZA200300085B ZA200300085B ZA200300085A ZA200300085A ZA200300085B ZA 200300085 B ZA200300085 B ZA 200300085B ZA 200300085 A ZA200300085 A ZA 200300085A ZA 200300085 A ZA200300085 A ZA 200300085A ZA 200300085 B ZA200300085 B ZA 200300085B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxyepiandrosterone
- epia
- substance
- composition
- hydroxy
- Prior art date
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- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0016022A GB2363983A (en) | 2000-06-29 | 2000-06-29 | Protection against neuronal damage using 7-hydroxyepiandrosterone |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200300085B true ZA200300085B (en) | 2004-04-21 |
Family
ID=9894707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200300085A ZA200300085B (en) | 2000-06-29 | 2003-01-03 | 7-hydroxyepiandrosterone having neuroprotective activity. |
Country Status (24)
Country | Link |
---|---|
US (2) | US7718639B2 (zh) |
EP (1) | EP1294382B1 (zh) |
JP (1) | JP4942905B2 (zh) |
KR (1) | KR100786284B1 (zh) |
CN (1) | CN100459980C (zh) |
AT (1) | ATE401897T1 (zh) |
AU (2) | AU2001267709B2 (zh) |
CA (1) | CA2414584C (zh) |
CY (1) | CY1108773T1 (zh) |
CZ (1) | CZ299676B6 (zh) |
DE (1) | DE60134979D1 (zh) |
DK (1) | DK1294382T3 (zh) |
ES (1) | ES2310182T3 (zh) |
GB (1) | GB2363983A (zh) |
HK (1) | HK1052300B (zh) |
HU (1) | HU227152B1 (zh) |
IL (2) | IL153541A0 (zh) |
NO (1) | NO327959B1 (zh) |
PL (1) | PL200699B1 (zh) |
PT (1) | PT1294382E (zh) |
RU (1) | RU2307654C2 (zh) |
SI (1) | SI1294382T1 (zh) |
WO (1) | WO2002000225A1 (zh) |
ZA (1) | ZA200300085B (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2363984A (en) * | 2000-06-29 | 2002-01-16 | Hunter Fleming Ltd | Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids |
GB2378898A (en) * | 2001-08-14 | 2003-02-26 | Hunter Fleming Ltd | Prophylactic and therapeutic use of hydroxysteroids |
EP1539183A4 (en) * | 2002-08-28 | 2007-04-25 | Hollis Eden Pharmaceuticals | THERAPEUTIC TREATMENT METHODS |
US20070231373A1 (en) * | 2004-04-28 | 2007-10-04 | Hunter-Fleming Limited | Transdermal Steriod for Formulation |
HUE026961T2 (en) | 2006-11-21 | 2016-07-28 | Umecrine Cognition Ab | Use of pregnant and androstane steroids for the manufacture of a medicament for the treatment of central nervous system disorders |
MX2009005753A (es) | 2006-11-30 | 2009-09-28 | Hunter Fleming Ltd | Modulacion de trayectorias metabolicas de prostaglandina/ciclooxig enasa. |
GB0623971D0 (en) * | 2006-11-30 | 2007-01-10 | Hunter Fleming Ltd | Modulation of prostaglandin/cyclooxygenase metabolic pathways |
Family Cites Families (33)
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YU243975A (en) | 1974-10-14 | 1982-06-30 | Schering Ag | Process for obtaining 7-hydroxyestradiols |
US5707983A (en) | 1990-08-29 | 1998-01-13 | Humanetics Corporation | Treatment of alzheimer's disease and modulation of immune system with Δ5-androstenes |
US5292730A (en) * | 1990-08-29 | 1994-03-08 | Humanetics Corporation | Modulation of immune system with Δ5-androstenes |
US5212167A (en) * | 1991-09-12 | 1993-05-18 | Trustees Of Boston University | Modulation of receptor-mediated ion transport |
US5532230A (en) | 1993-03-09 | 1996-07-02 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
US5846963A (en) | 1995-06-07 | 1998-12-08 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
US5387583A (en) * | 1993-04-20 | 1995-02-07 | Loria; Roger M. | Compositions containing corticosteroids or analogues thereof and corticosteroid buffering effective amounts of 5-androstene 3B, 17B or 5-androstene 3B, 7B, 17B triol or analogues thereof |
US5877169A (en) | 1993-11-05 | 1999-03-02 | University Of Florida Research Foundation, Inc. | Methods of treatment of ischemic damage |
US5554601A (en) | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
US5976850A (en) | 1994-10-19 | 1999-11-02 | University Of Edinburgh | Hippocampus-associated proteins; DNA sequences coding therefor and uses thereof |
US5556847A (en) * | 1994-10-27 | 1996-09-17 | Duquesne University Of The Holy Ghost | Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors |
GEP20012530B (en) | 1995-06-06 | 2001-09-25 | Cocensys Inc | Neuroactive Steroids of the Androstane and Pregnane Series |
EP0840612A1 (en) | 1995-07-24 | 1998-05-13 | Trustees Of Boston University | Inhibition of nmda receptor activity by pregnenolone sulfate derivatives |
GB2317826B (en) * | 1995-08-29 | 1999-12-15 | Univ Edinburgh | Regulation of intracellular glucocorticoid concentrations |
US5985242A (en) | 1995-10-27 | 1999-11-16 | Praecis Pharmaceuticals, Inc. | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
NZ331975A (en) * | 1996-04-09 | 2000-12-22 | Btg Int Ltd | Use of 7 alpha-substituted steroids to treat neuropsychriatic disorders or enhance cognition |
EP0929574B1 (en) | 1996-08-27 | 2005-06-29 | Praecis Pharmaceuticals Incorporated | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS |
FR2760362B1 (fr) | 1997-03-10 | 2000-08-11 | Vitasterol | Utilisation cosmetique ou dermatologique de steroides 7-hydroxyles |
WO1998043647A1 (en) * | 1997-03-28 | 1998-10-08 | Massachusetts Institute Of Technology, Inc. | Regulation of amyloid precursor protein (app) expression by estrogenic compounds |
GB9708716D0 (en) * | 1997-04-29 | 1997-06-18 | Imperial College | Chronic heart failure |
WO1999015179A1 (en) * | 1997-09-25 | 1999-04-01 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
WO1999024400A1 (en) | 1997-11-10 | 1999-05-20 | Vyrex Corporation | Probucol esters and uses thereof |
EP1032397A1 (en) * | 1997-11-24 | 2000-09-06 | University Of Florida Research Foundation, Inc. | Testosterone inhibitors and use for the protection of neurons |
GB9726569D0 (en) | 1997-12-16 | 1998-02-11 | Univ Southampton | Neuroprotective agents |
WO1999052532A1 (en) * | 1998-04-14 | 1999-10-21 | Pharmadigm, Inc. | Method for reducing central nervous system impairment |
FR2786102B1 (fr) * | 1998-11-20 | 2001-02-16 | Monique Vincens | Utilisation de sulfate de dehydroepiandrosterone pour augmenter le nombre de recepteurs nmda chez un mammifere |
US6667299B1 (en) | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
US20030083231A1 (en) | 1998-11-24 | 2003-05-01 | Ahlem Clarence N. | Blood cell deficiency treatment method |
ATE361309T1 (de) | 1999-11-02 | 2007-05-15 | Bayer Schering Pharma Ag | 18-nor-steroide als selektiv wirksame estrogene |
GB0003524D0 (en) | 2000-02-15 | 2000-04-05 | Btg Int Ltd | Cytoprotective steroids (II) |
GB2363984A (en) | 2000-06-29 | 2002-01-16 | Hunter Fleming Ltd | Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids |
EP1557166A1 (en) * | 2004-01-21 | 2005-07-27 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders |
-
2000
- 2000-06-29 GB GB0016022A patent/GB2363983A/en not_active Withdrawn
-
2001
- 2001-06-29 CA CA002414584A patent/CA2414584C/en not_active Expired - Fee Related
- 2001-06-29 JP JP2002505007A patent/JP4942905B2/ja not_active Expired - Fee Related
- 2001-06-29 US US10/312,533 patent/US7718639B2/en not_active Expired - Fee Related
- 2001-06-29 PL PL359108A patent/PL200699B1/pl not_active IP Right Cessation
- 2001-06-29 WO PCT/GB2001/002937 patent/WO2002000225A1/en active IP Right Grant
- 2001-06-29 EP EP01945494A patent/EP1294382B1/en not_active Expired - Lifetime
- 2001-06-29 DK DK01945494T patent/DK1294382T3/da active
- 2001-06-29 CN CNB018121098A patent/CN100459980C/zh not_active Expired - Fee Related
- 2001-06-29 DE DE60134979T patent/DE60134979D1/de not_active Expired - Lifetime
- 2001-06-29 AU AU2001267709A patent/AU2001267709B2/en not_active Ceased
- 2001-06-29 HU HU0301134A patent/HU227152B1/hu not_active IP Right Cessation
- 2001-06-29 ES ES01945494T patent/ES2310182T3/es not_active Expired - Lifetime
- 2001-06-29 IL IL15354101A patent/IL153541A0/xx active IP Right Grant
- 2001-06-29 CZ CZ20030077A patent/CZ299676B6/cs not_active IP Right Cessation
- 2001-06-29 PT PT01945494T patent/PT1294382E/pt unknown
- 2001-06-29 RU RU2003102437/15A patent/RU2307654C2/ru not_active IP Right Cessation
- 2001-06-29 KR KR1020027017898A patent/KR100786284B1/ko not_active IP Right Cessation
- 2001-06-29 AU AU6770901A patent/AU6770901A/xx active Pending
- 2001-06-29 SI SI200130866T patent/SI1294382T1/sl unknown
- 2001-06-29 AT AT01945494T patent/ATE401897T1/de active
-
2002
- 2002-12-19 IL IL153541A patent/IL153541A/en not_active IP Right Cessation
- 2002-12-27 NO NO20026243A patent/NO327959B1/no not_active IP Right Cessation
-
2003
- 2003-01-03 ZA ZA200300085A patent/ZA200300085B/en unknown
- 2003-06-26 HK HK03104578.9A patent/HK1052300B/zh not_active IP Right Cessation
-
2008
- 2008-10-20 CY CY20081101165T patent/CY1108773T1/el unknown
-
2009
- 2009-12-16 US US12/639,708 patent/US20100173883A1/en not_active Abandoned
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