ZA200208847B - Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses. - Google Patents

Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses. Download PDF

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Publication number
ZA200208847B
ZA200208847B ZA200208847A ZA200208847A ZA200208847B ZA 200208847 B ZA200208847 B ZA 200208847B ZA 200208847 A ZA200208847 A ZA 200208847A ZA 200208847 A ZA200208847 A ZA 200208847A ZA 200208847 B ZA200208847 B ZA 200208847B
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ZA
South Africa
Prior art keywords
nucleic acid
nucleotide
isolated nucleic
polynucleotide
transcription
Prior art date
Application number
ZA200208847A
Other languages
English (en)
Inventor
Marie-Francoise Rosier-Montus
Cendrine Lemoine
Patrice Denefle
Nicolas Duverger
Silvia Santamarina-Fojo
Catherine Prades
Laurent Naudin
Bryan Brewer
Alan Remaley
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ZA200208847B publication Critical patent/ZA200208847B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200208847A 2000-05-02 2002-10-31 Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses. ZA200208847B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20128000P 2000-05-02 2000-05-02

Publications (1)

Publication Number Publication Date
ZA200208847B true ZA200208847B (en) 2004-02-09

Family

ID=22745217

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200208847A ZA200208847B (en) 2000-05-02 2002-10-31 Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses.

Country Status (14)

Country Link
US (1) US7378274B2 (pt)
EP (1) EP1280911A2 (pt)
JP (1) JP2003531613A (pt)
KR (1) KR20020097242A (pt)
AU (1) AU785155B2 (pt)
BR (1) BR0110541A (pt)
CA (1) CA2407737A1 (pt)
FR (1) FR2809414B1 (pt)
IL (1) IL152548A0 (pt)
MX (1) MXPA02010684A (pt)
NO (1) NO20025265L (pt)
NZ (1) NZ522360A (pt)
WO (1) WO2001083746A2 (pt)
ZA (1) ZA200208847B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4726302B2 (ja) 1999-03-15 2011-07-20 ユニバーシティ オブ ブリティッシュ コロンビア Abc1ポリペプチドおよびコレステロール水準を調節する方法と試薬
EP1854880A1 (en) * 1999-03-15 2007-11-14 University of British Columbia Methods and reagents for modulating cholesterol levels
US6821774B1 (en) 1999-06-18 2004-11-23 Cv Therapeutics, Inc. Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter ABC1
US6835563B1 (en) * 1999-06-18 2004-12-28 Cv Therapeutics Compositions and methods for increasing cholesterol efflux and raising HDL ATP binding cassette transporter protein ABC1
AU777461B2 (en) * 1999-06-18 2004-10-14 Gilead Palo Alto, Inc. Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter protein ABC1
AU1291901A (en) * 1999-09-01 2001-03-26 University Of British Columbia, The Compositions and methods for modulating hdl cholesterol and triglyceride levels

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872237A (en) * 1996-04-04 1999-02-16 Mercator Genetics, Inc. Megabase transcript map: novel sequences and antibodies thereto
JP4726302B2 (ja) * 1999-03-15 2011-07-20 ユニバーシティ オブ ブリティッシュ コロンビア Abc1ポリペプチドおよびコレステロール水準を調節する方法と試薬
AU777461B2 (en) 1999-06-18 2004-10-14 Gilead Palo Alto, Inc. Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter protein ABC1
AU1291901A (en) * 1999-09-01 2001-03-26 University Of British Columbia, The Compositions and methods for modulating hdl cholesterol and triglyceride levels
US6773893B1 (en) * 2000-04-28 2004-08-10 The Trustees Of Columbia University In The City Of New York Human ABC1 promoter and assays based thereon

Also Published As

Publication number Publication date
MXPA02010684A (es) 2003-03-10
NO20025265D0 (no) 2002-11-01
JP2003531613A (ja) 2003-10-28
WO2001083746A2 (en) 2001-11-08
EP1280911A2 (en) 2003-02-05
FR2809414B1 (fr) 2007-08-31
NZ522360A (en) 2004-12-24
AU785155B2 (en) 2006-10-05
US7378274B2 (en) 2008-05-27
IL152548A0 (en) 2003-05-29
KR20020097242A (ko) 2002-12-31
BR0110541A (pt) 2003-04-01
WO2001083746A3 (en) 2002-06-27
CA2407737A1 (en) 2001-11-08
US20020146792A1 (en) 2002-10-10
NO20025265L (no) 2002-12-18
FR2809414A1 (fr) 2001-11-30
AU6595601A (en) 2001-11-12

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