ZA200201189B - Ophthalmic drug delivery device. - Google Patents
Ophthalmic drug delivery device. Download PDFInfo
- Publication number
- ZA200201189B ZA200201189B ZA200201189A ZA200201189A ZA200201189B ZA 200201189 B ZA200201189 B ZA 200201189B ZA 200201189 A ZA200201189 A ZA 200201189A ZA 200201189 A ZA200201189 A ZA 200201189A ZA 200201189 B ZA200201189 B ZA 200201189B
- Authority
- ZA
- South Africa
- Prior art keywords
- drug delivery
- delivery device
- pharmaceutically active
- active agent
- sclera
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title claims description 68
- 239000003732 agents acting on the eye Substances 0.000 title claims description 44
- 229940023490 ophthalmic product Drugs 0.000 title claims description 43
- 239000013543 active substance Substances 0.000 claims description 63
- 210000003205 muscle Anatomy 0.000 claims description 58
- 210000003786 sclera Anatomy 0.000 claims description 36
- 206010025421 Macule Diseases 0.000 claims description 16
- 238000002513 implantation Methods 0.000 claims description 14
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- 239000000203 mixture Substances 0.000 claims description 11
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- 229920006397 acrylic thermoplastic Polymers 0.000 claims description 3
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 claims description 3
- 229960001002 nepafenac Drugs 0.000 claims description 3
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 3
- -1 polypropylene Polymers 0.000 claims description 3
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 claims description 3
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 claims description 3
- GGUSQTSTQSHJAH-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol Chemical compound C=1C=C(Cl)C=CC=1C(O)CN(CC1)CCC1CC1=CC=C(F)C=C1 GGUSQTSTQSHJAH-UHFFFAOYSA-N 0.000 claims description 2
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- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 2
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- LCSKNASZPVZHEG-UHFFFAOYSA-N 3,6-dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione Chemical group O=C1COC(=O)CO1.CC1OC(=O)C(C)OC1=O LCSKNASZPVZHEG-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00891—Glaucoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16067399P | 1999-10-21 | 1999-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200201189B true ZA200201189B (en) | 2003-02-12 |
Family
ID=22577913
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200201188A ZA200201188B (en) | 1999-10-21 | 2002-02-12 | Drug delivery device. |
ZA200201189A ZA200201189B (en) | 1999-10-21 | 2002-02-12 | Ophthalmic drug delivery device. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200201188A ZA200201188B (en) | 1999-10-21 | 2002-02-12 | Drug delivery device. |
Country Status (22)
Country | Link |
---|---|
US (3) | US6413540B1 (da) |
EP (2) | EP1221917B1 (da) |
JP (1) | JP4837861B2 (da) |
KR (1) | KR100732262B1 (da) |
CN (1) | CN1292721C (da) |
AR (3) | AR026165A1 (da) |
AT (2) | ATE414494T1 (da) |
AU (2) | AU768400B2 (da) |
BR (1) | BR0014929B1 (da) |
CA (1) | CA2383499C (da) |
CY (1) | CY1109489T1 (da) |
DE (2) | DE60016271T2 (da) |
DK (1) | DK1473003T3 (da) |
ES (2) | ES2315598T3 (da) |
HK (2) | HK1048427B (da) |
MX (1) | MXPA02002338A (da) |
PL (1) | PL196988B1 (da) |
PT (2) | PT1473003E (da) |
TR (1) | TR200201047T2 (da) |
TW (1) | TW555575B (da) |
WO (1) | WO2001028472A1 (da) |
ZA (2) | ZA200201188B (da) |
Families Citing this family (182)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1104302A4 (en) * | 1998-07-10 | 2006-08-09 | Retmed Pty Ltd | PROPHYLACTIC TREATMENTS OF BLOOD VESSEL NEOFORMATION IN MACULAR DEGENERATION |
ES2609594T3 (es) | 1999-04-26 | 2017-04-21 | Glaukos Corporation | Dispositivo de drenaje para tratar el glaucoma |
US6416777B1 (en) * | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
DE60016271T2 (de) * | 1999-10-21 | 2005-12-01 | Alcon Inc. | Medikamentenzuführvorrichtung |
US7943162B2 (en) | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
US20020143284A1 (en) * | 2001-04-03 | 2002-10-03 | Hosheng Tu | Drug-releasing trabecular implant for glaucoma treatment |
AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
JP2004517674A (ja) * | 2000-12-29 | 2004-06-17 | ボシュ・アンド・ロム・インコーポレイテッド | 徐放薬物送達装置 |
US6964781B2 (en) * | 2001-01-03 | 2005-11-15 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
WO2002053128A2 (en) | 2001-01-03 | 2002-07-11 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with multiple agents |
WO2002058667A2 (en) * | 2001-01-26 | 2002-08-01 | Bausch & Lomb Incorporated | Improved process for the production of sustained release drug delivery devices |
EP2982354A1 (en) | 2001-04-07 | 2016-02-10 | Glaukos Corporation | System for treating ocular disorders |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US7488303B1 (en) * | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
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- 2000-09-12 EP EP00961836A patent/EP1221917B1/en not_active Expired - Lifetime
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- 2000-09-12 AU AU73733/00A patent/AU768400B2/en not_active Ceased
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- 2000-09-12 MX MXPA02002338A patent/MXPA02002338A/es active IP Right Grant
- 2000-09-12 JP JP2001531069A patent/JP4837861B2/ja not_active Expired - Fee Related
- 2000-09-12 US US09/660,000 patent/US6413540B1/en not_active Expired - Lifetime
- 2000-09-12 AT AT04018677T patent/ATE414494T1/de active
- 2000-09-12 PL PL355263A patent/PL196988B1/pl not_active IP Right Cessation
- 2000-09-12 AT AT00961836T patent/ATE283013T1/de active
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- 2000-09-12 WO PCT/US2000/024983 patent/WO2001028472A1/en active IP Right Grant
- 2000-09-12 KR KR1020027005020A patent/KR100732262B1/ko not_active IP Right Cessation
- 2000-09-12 EP EP04018677A patent/EP1473003B1/en not_active Expired - Lifetime
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- 2000-09-12 DK DK04018677T patent/DK1473003T3/da active
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2002
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2003
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2004
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