ZA200110074B - Therapeutic agent comprising a botulinum neurotoxin. - Google Patents

Therapeutic agent comprising a botulinum neurotoxin.

Info

Publication number
ZA200110074B
ZA200110074B ZA200110074A ZA200110074A ZA200110074B ZA 200110074 B ZA200110074 B ZA 200110074B ZA 200110074 A ZA200110074 A ZA 200110074A ZA 200110074 A ZA200110074 A ZA 200110074A ZA 200110074 B ZA200110074 B ZA 200110074B
Authority
ZA
South Africa
Prior art keywords
therapeutic agent
botulinum neurotoxin
neurotoxin
botulinum
therapeutic
Prior art date
Application number
ZA200110074A
Other languages
English (en)
Inventor
Hans Bigalke
Juergen Frevert
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7910318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200110074(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of ZA200110074B publication Critical patent/ZA200110074B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200110074A 1999-06-07 2001-12-06 Therapeutic agent comprising a botulinum neurotoxin. ZA200110074B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19925739A DE19925739A1 (de) 1999-06-07 1999-06-07 Therapeutikum mit einem Botulinum-Neurotoxin

Publications (1)

Publication Number Publication Date
ZA200110074B true ZA200110074B (en) 2003-03-06

Family

ID=7910318

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200110074A ZA200110074B (en) 1999-06-07 2001-12-06 Therapeutic agent comprising a botulinum neurotoxin.

Country Status (26)

Country Link
US (3) US7964199B1 (https=)
EP (1) EP1185291B2 (https=)
JP (2) JP2003505343A (https=)
KR (1) KR100466407B1 (https=)
CN (2) CN100389820C (https=)
AR (1) AR024306A1 (https=)
AT (1) ATE258803T1 (https=)
AU (1) AU774590B2 (https=)
CA (1) CA2376193C (https=)
CO (1) CO5170431A1 (https=)
CZ (1) CZ20014351A3 (https=)
DE (3) DE19925739A1 (https=)
DK (1) DK1185291T3 (https=)
EA (1) EA004202B1 (https=)
ES (1) ES2215056T5 (https=)
GE (1) GEP20043200B (https=)
HU (1) HUP0201530A3 (https=)
IL (2) IL146974A0 (https=)
MX (1) MXPA01012540A (https=)
NO (1) NO20015964L (https=)
PL (1) PL198958B1 (https=)
PT (1) PT1185291E (https=)
TW (1) TWI251492B (https=)
UA (1) UA72253C2 (https=)
WO (1) WO2000074703A2 (https=)
ZA (1) ZA200110074B (https=)

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US6821520B2 (en) 2000-02-15 2004-11-23 Allergan, Inc. Clostridial toxin therapy for Hashimoto's thyroiditis
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US7140371B2 (en) 2002-03-14 2006-11-28 Allergan, Inc. Surface topography method for determining effects of a botulinum toxin upon a muscle and for comparing botulinum toxins
US6688311B2 (en) 2002-03-14 2004-02-10 Allergan, Inc. Method for determining effect of a clostridial toxin upon a muscle
US20050163809A1 (en) * 2002-03-29 2005-07-28 Ryuji Kaji Remedy for hypermyotonia
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US8071550B2 (en) 2003-03-03 2011-12-06 Allergan, Inc. Methods for treating uterine disorders
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BR112022023413A2 (pt) 2020-06-05 2022-12-20 Merz Pharma Gmbh & Co Kgaa Tratamento de rugas faciais com toxina botulínica de alta dose e baixo volume
KR102724651B1 (ko) * 2021-07-08 2024-11-01 주식회사 파마리서치바이오 비-독소 단백질이 제거된 클로스트리디움 보툴리눔 신경독소 단백질의 정제방법
TW202400122A (zh) 2022-02-28 2024-01-01 德商梅茲製藥有限兩合公司 肉毒桿菌毒素用於降低皮膚毛孔尺寸及／或皮脂產生之用途、以及降低皮膚毛孔尺寸及／或皮脂產生的方法
AR131172A1 (es) 2022-11-28 2025-02-19 Merz Pharma Gmbh & Co Kgaa Inyección de toxina botulínica en el platisma para el rejuvenecimiento del rostro inferior y del cuello
IL320937A (en) 2022-11-28 2025-07-01 Merz Pharma Gmbh & Co Kgaa High-concentration botulinum toxin treatment for neck rejuvenation
WO2024194181A1 (en) 2023-03-20 2024-09-26 Merz Therapeutics GmbH Nh3 scavenger for use in the treatment of mobility disability in a post-stroke patient
WO2024240868A1 (en) 2023-05-23 2024-11-28 Merz Therapeutics GmbH Botulinum toxin for treating peripheral neuropathic pain
CN121511091A (zh) 2023-07-12 2026-02-10 莫茨药物股份两合公司 通过肉毒杆菌毒素的色素沉着过度病况治疗
WO2025228877A1 (en) 2024-04-29 2025-11-06 Merz Therapeutics GmbH Botulinum toxin for the preventive treatment of migraine
WO2026021713A1 (en) 2024-07-23 2026-01-29 Merz Therapeutics GmbH Uses of magnetic nerve stimulation associated with botulinum neurotoxin administration

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DE19925739A1 (de) 2000-12-21
CN100389820C (zh) 2008-05-28
AR024306A1 (es) 2002-09-25
US7964199B1 (en) 2011-06-21
JP2007238627A (ja) 2007-09-20
EA200200017A1 (ru) 2002-06-27
EP1185291B2 (de) 2010-10-27
PL352468A1 (en) 2003-08-25
WO2000074703B1 (de) 2001-06-07
ES2215056T3 (es) 2004-10-01
US20110217287A1 (en) 2011-09-08
WO2000074703A3 (de) 2001-04-26
CZ20014351A3 (cs) 2002-06-12
UA72253C2 (uk) 2005-02-15
WO2000074703A2 (de) 2000-12-14
GEP20043200B (en) 2004-03-25
PL198958B1 (pl) 2008-08-29
EP1185291B1 (de) 2004-02-04
HUP0201530A3 (en) 2002-10-28
DK1185291T3 (da) 2004-04-05
IL146974A (en) 2007-05-15
JP2003505343A (ja) 2003-02-12
NO20015964D0 (no) 2001-12-06
HUP0201530A2 (en) 2002-09-28
CO5170431A1 (es) 2002-06-27
NO20015964L (no) 2002-01-30
MXPA01012540A (es) 2004-09-27
ES2215056T5 (es) 2011-03-15
HK1047403A1 (zh) 2003-02-21
AU774590B2 (en) 2004-07-01
US8398998B2 (en) 2013-03-19
PT1185291E (pt) 2004-06-30
KR20020008214A (ko) 2002-01-29
CA2376193A1 (en) 2000-12-14
CA2376193C (en) 2008-09-16
KR100466407B1 (ko) 2005-01-27
IL146974A0 (en) 2002-08-14
EP1185291A2 (de) 2002-03-13
CN101062009A (zh) 2007-10-31
TWI251492B (en) 2006-03-21
CN1354670A (zh) 2002-06-19
DE10081516D2 (de) 2001-09-13
DE50005208D1 (de) 2004-03-11
ATE258803T1 (de) 2004-02-15
EA004202B1 (ru) 2004-02-26
US20120088732A1 (en) 2012-04-12
AU5804700A (en) 2000-12-28

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