ZA200106596B - Use of 15-Deoxyspergualin for the treatment of hypUse of 15-deoxyspergualin for the treatment of hyperactive inflammatory diseases and autoimmune diseerreactive inflammatory diseases and autoimmune diases. seases. - Google Patents

Use of 15-Deoxyspergualin for the treatment of hypUse of 15-deoxyspergualin for the treatment of hyperactive inflammatory diseases and autoimmune diseerreactive inflammatory diseases and autoimmune diases. seases. Download PDF

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Publication number
ZA200106596B
ZA200106596B ZA200106596A ZA200106596A ZA200106596B ZA 200106596 B ZA200106596 B ZA 200106596B ZA 200106596 A ZA200106596 A ZA 200106596A ZA 200106596 A ZA200106596 A ZA 200106596A ZA 200106596 B ZA200106596 B ZA 200106596B
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South Africa
Prior art keywords
treatment
use according
blood
level
peripheral blood
Prior art date
Application number
ZA200106596A
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English (en)
Inventor
Rainer Birck Rainer Birck
Johannes Drexler Johan Drexler
Osamu Hotta Osamu Hotta
Rainer Nowack Rainer Nowack
Johannes Fokku Van Der W Woude
Original Assignee
Nippon Kayaku Kk
Euro Nippon Kayaku Gmbh Euro N
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Publication date
Application filed by Nippon Kayaku Kk, Euro Nippon Kayaku Gmbh Euro N filed Critical Nippon Kayaku Kk
Publication of ZA200106596B publication Critical patent/ZA200106596B/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200106596A 1999-05-25 2001-08-10 Use of 15-Deoxyspergualin for the treatment of hypUse of 15-deoxyspergualin for the treatment of hyperactive inflammatory diseases and autoimmune diseerreactive inflammatory diseases and autoimmune diases. seases. ZA200106596B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19923961A DE19923961A1 (de) 1999-05-25 1999-05-25 Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen

Publications (1)

Publication Number Publication Date
ZA200106596B true ZA200106596B (en) 2002-08-12

Family

ID=7909146

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200106596A ZA200106596B (en) 1999-05-25 2001-08-10 Use of 15-Deoxyspergualin for the treatment of hypUse of 15-deoxyspergualin for the treatment of hyperactive inflammatory diseases and autoimmune diseerreactive inflammatory diseases and autoimmune diases. seases.

Country Status (20)

Country Link
US (2) US7153887B1 (hu)
EP (1) EP1180026B1 (hu)
JP (2) JP4422349B2 (hu)
KR (1) KR100681626B1 (hu)
CN (1) CN1199636C (hu)
AR (1) AR024071A1 (hu)
AT (1) ATE228833T1 (hu)
AU (1) AU762018B2 (hu)
BR (1) BR0008637A (hu)
CA (1) CA2362582C (hu)
CZ (1) CZ299440B6 (hu)
DE (2) DE19923961A1 (hu)
ES (1) ES2188538T3 (hu)
HU (1) HU228843B1 (hu)
MX (1) MXPA01008587A (hu)
PL (1) PL352314A1 (hu)
RU (1) RU2255732C2 (hu)
TW (1) TWI283175B (hu)
WO (1) WO2000071103A2 (hu)
ZA (1) ZA200106596B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1689435A4 (en) * 2003-10-22 2007-10-03 Univ Rochester ANTI-THYMOCYTE ANTISERUM AND ITS USE FOR TRIGGERING B-CELL APOPTOSIS
AR048210A1 (es) * 2003-12-19 2006-04-12 Chugai Pharmaceutical Co Ltd Un agente preventivo para la vasculitis.
EP2380585B1 (en) * 2006-04-12 2015-07-08 Genzyme Corporation Methods of treating autoimmune diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083503A (en) * 1991-08-28 2000-07-04 The United States Of America As Represented By The Department Of Health And Human Services Interleukin-2 stimulated T lymphocyte cell death for the treatment of autoimmune diseases, allergic responses, and graft rejection
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
US5250442A (en) * 1993-04-08 1993-10-05 Orestes Cabezas Method of treating rheumatoid arthritis using tetracycline
FR2716452B1 (fr) * 1994-02-24 1996-05-10 Fournier Ind & Sante Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
US5505715A (en) * 1994-02-25 1996-04-09 Bristol-Myers Squibb Company Iontophoretic transdermal delivery of deoxyspergualin compounds
ES2124926T3 (es) * 1994-03-22 1999-02-16 Nippon Kayaku Kk Uso de desoxipergualina para la preparacion de un medicamento para el tratamiento de enfermedades inflamatorias e hiperreactivas.
US5624938A (en) * 1994-07-18 1997-04-29 The Trustees Of Columbia University In The City Of New York Use of chloroquine to treat multiple sclerosis
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
US5679651A (en) * 1995-06-05 1997-10-21 Richardson; Bruce C. Treatment for systemic lupus erythematosus
DE19711803A1 (de) * 1997-03-21 1998-09-24 Hoechst Ag Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung mit 15-Deoxyspergualin
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
TW536400B (en) * 1997-07-18 2003-06-11 Nippon Kayaku Kk Pharmaceutical composition for the treatment of immunodeficiency disease which cause by HIV infection

Also Published As

Publication number Publication date
ATE228833T1 (de) 2002-12-15
HUP0200354A2 (hu) 2002-05-29
CZ299440B6 (cs) 2008-07-30
KR100681626B1 (ko) 2007-02-09
WO2000071103A2 (en) 2000-11-30
US7776829B2 (en) 2010-08-17
KR20020010126A (ko) 2002-02-02
US7153887B1 (en) 2006-12-26
AU762018B2 (en) 2003-06-19
US20060293391A1 (en) 2006-12-28
PL352314A1 (en) 2003-08-11
CN1199636C (zh) 2005-05-04
DE60000937T2 (de) 2003-09-04
DE60000937D1 (de) 2003-01-16
AR024071A1 (es) 2002-09-04
HUP0200354A3 (en) 2003-03-28
MXPA01008587A (es) 2003-06-24
CN1351490A (zh) 2002-05-29
EP1180026A2 (en) 2002-02-20
DE19923961A1 (de) 2000-11-30
ES2188538T3 (es) 2003-07-01
WO2000071103A3 (en) 2001-06-21
CA2362582C (en) 2008-10-07
CA2362582A1 (en) 2000-11-30
BR0008637A (pt) 2002-01-08
CZ20014158A3 (cs) 2002-06-12
RU2255732C2 (ru) 2005-07-10
JP4422349B2 (ja) 2010-02-24
JP2009263397A (ja) 2009-11-12
HU228843B1 (en) 2013-06-28
TWI283175B (en) 2007-07-01
AU4550400A (en) 2000-12-12
EP1180026B1 (en) 2002-12-04
JP2003500351A (ja) 2003-01-07

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