ZA200100239B - Therapeutic composition based on flavonoids for use in the treatment of tumors with cytotoxic agents. - Google Patents
Therapeutic composition based on flavonoids for use in the treatment of tumors with cytotoxic agents. Download PDFInfo
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- ZA200100239B ZA200100239B ZA200100239A ZA200100239A ZA200100239B ZA 200100239 B ZA200100239 B ZA 200100239B ZA 200100239 A ZA200100239 A ZA 200100239A ZA 200100239 A ZA200100239 A ZA 200100239A ZA 200100239 B ZA200100239 B ZA 200100239B
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- South Africa
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- infusion
- flavonoid
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- 230000003637 steroidlike Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 201000000498 stomach carcinoma Diseases 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 229960001052 streptozocin Drugs 0.000 description 1
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229960001603 tamoxifen Drugs 0.000 description 1
- 229940005505 tamoxifen 20 mg Drugs 0.000 description 1
- XGZAXRQNRRXUMY-MJCKVQKWSA-J tetrasodium;[4-[(e)-4-(4-phosphonatooxyphenyl)hex-3-en-3-yl]phenyl] phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].C=1C=C(OP([O-])([O-])=O)C=CC=1C(/CC)=C(\CC)C1=CC=C(OP([O-])([O-])=O)C=C1 XGZAXRQNRRXUMY-MJCKVQKWSA-J 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 150000003918 triazines Chemical class 0.000 description 1
- 230000001573 trophoblastic effect Effects 0.000 description 1
- 231100000588 tumorigenic Toxicity 0.000 description 1
- 230000000381 tumorigenic effect Effects 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- BXDTXNJFFKRYAP-BCJYHSTASA-N vad protocol Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O.O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.C([C@H](C[C@]1(C(=O)OC)C=2C(=C3C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C=O)=CC=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 BXDTXNJFFKRYAP-BCJYHSTASA-N 0.000 description 1
- GBABOYUKABKIAF-IELIFDKJSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-IELIFDKJSA-N 0.000 description 1
- 229960002066 vinorelbine Drugs 0.000 description 1
- 229960000641 zorubicin Drugs 0.000 description 1
- FBTUMDXHSRTGRV-ALTNURHMSA-N zorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(\C)=N\NC(=O)C=1C=CC=CC=1)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 FBTUMDXHSRTGRV-ALTNURHMSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9809058A FR2781153B1 (fr) | 1998-07-15 | 1998-07-15 | Composition therapeutique a base de flavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200100239B true ZA200100239B (en) | 2002-01-09 |
Family
ID=9528648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200100239A ZA200100239B (en) | 1998-07-15 | 2001-01-09 | Therapeutic composition based on flavonoids for use in the treatment of tumors with cytotoxic agents. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1096930A1 (zh) |
| JP (1) | JP2002520356A (zh) |
| KR (1) | KR20020003349A (zh) |
| CN (1) | CN1139384C (zh) |
| AU (1) | AU4789099A (zh) |
| BR (1) | BR9912816A (zh) |
| CA (1) | CA2337179A1 (zh) |
| EA (1) | EA200100140A1 (zh) |
| FR (1) | FR2781153B1 (zh) |
| IL (1) | IL140588A0 (zh) |
| WO (1) | WO2000003706A1 (zh) |
| ZA (1) | ZA200100239B (zh) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002069949A2 (en) * | 2001-03-06 | 2002-09-12 | Prendergast Patrick T | Combination therapy for reduction of toxycity of chemotherapeutic agents |
| EP1808172A3 (en) * | 2002-03-06 | 2010-05-26 | Activephyto Technologies Limited | Botanical extract compositions and methods of use |
| AU2003217982A1 (en) * | 2002-03-06 | 2003-09-22 | The Medical Research And Education Trust | Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising wogonin, isoliquiritigenin and/or coumestrol |
| US20030229136A1 (en) | 2002-04-18 | 2003-12-11 | Nurulain Zaveri | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
| CN1679539A (zh) * | 2005-01-20 | 2005-10-12 | 吴一心 | 抗肿瘤的协同药物组合物 |
| CA2600797A1 (en) * | 2005-03-11 | 2006-09-21 | The Regents Of The University Of Michigan | Chromen-4-one inhibitors of anti-apoptotic bcl-2 family members and the uses thereof |
| GB0808974D0 (en) * | 2008-05-16 | 2008-06-25 | Veritron Ltd | Plant extract and its therapeutic use |
| US9808477B2 (en) * | 2015-07-29 | 2017-11-07 | Macau University Of Science And Technology | Use of nobiletin in cancer treatment |
| US9808439B2 (en) * | 2015-07-29 | 2017-11-07 | Macau University Of Science And Technology | Use of tangeretin in cancer treatment |
| JP6775226B2 (ja) * | 2016-06-30 | 2020-10-28 | 国立大学法人広島大学 | 抗癌剤作用増強物質およびそれを備えた抗癌剤キット |
| CN106562954A (zh) * | 2016-11-11 | 2017-04-19 | 黄冈师范学院 | (去甲基)多甲氧基黄酮联合紫杉醇类药物在制备治疗非小细胞肺癌的药物上的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0617304B2 (ja) * | 1982-09-09 | 1994-03-09 | 理化学研究所 | 制癌剤 |
| JPS5959627A (ja) * | 1982-09-27 | 1984-04-05 | Tatsuo Miyoshi | 制癌剤 |
| JPS60199817A (ja) * | 1984-03-23 | 1985-10-09 | Rikagaku Kenkyusho | 制癌剤 |
| JPS632925A (ja) * | 1986-06-23 | 1988-01-07 | Nippon Kayaku Co Ltd | Ｃキナ−ゼ阻害剤および抗腫瘍剤 |
| FR2633182B1 (fr) * | 1988-06-23 | 1993-07-23 | Beljanski Mirko | Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention |
| JPH04103532A (ja) * | 1990-08-24 | 1992-04-06 | Tatsuo Miyoshi | 制癌剤 |
| JPH04103529A (ja) * | 1990-08-24 | 1992-04-06 | Tatsuo Miyoshi | 制癌剤 |
| JP2514500B2 (ja) * | 1991-09-14 | 1996-07-10 | 呉羽化学工業株式会社 | 多剤耐性抑制剤及び発現阻害剤 |
| EP0642793A4 (en) * | 1992-05-11 | 1995-03-29 | Tsumura & Co. | Apoptosis inducer. |
| WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
| DE29719198U1 (de) * | 1997-10-29 | 1998-04-23 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, 14558 Bergholz-Rehbrücke | Flavono/Flavonoid-Zubereitung |
-
1998
- 1998-07-15 FR FR9809058A patent/FR2781153B1/fr not_active Expired - Fee Related
-
1999
- 1999-07-13 KR KR1020017000478A patent/KR20020003349A/ko not_active Application Discontinuation
- 1999-07-13 AU AU47890/99A patent/AU4789099A/en not_active Abandoned
- 1999-07-13 CA CA002337179A patent/CA2337179A1/en not_active Abandoned
- 1999-07-13 JP JP2000559841A patent/JP2002520356A/ja active Pending
- 1999-07-13 BR BR9912816-0A patent/BR9912816A/pt not_active IP Right Cessation
- 1999-07-13 EA EA200100140A patent/EA200100140A1/ru unknown
- 1999-07-13 EP EP99931342A patent/EP1096930A1/fr not_active Withdrawn
- 1999-07-13 WO PCT/FR1999/001714 patent/WO2000003706A1/fr not_active Application Discontinuation
- 1999-07-13 CN CNB998098353A patent/CN1139384C/zh not_active Expired - Fee Related
- 1999-07-13 IL IL14058899A patent/IL140588A0/xx unknown
-
2001
- 2001-01-09 ZA ZA200100239A patent/ZA200100239B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4789099A (en) | 2000-02-07 |
| JP2002520356A (ja) | 2002-07-09 |
| CN1139384C (zh) | 2004-02-25 |
| EA200100140A1 (ru) | 2001-06-25 |
| FR2781153B1 (fr) | 2001-08-03 |
| IL140588A0 (en) | 2002-02-10 |
| KR20020003349A (ko) | 2002-01-12 |
| CN1313765A (zh) | 2001-09-19 |
| CA2337179A1 (en) | 2000-01-27 |
| WO2000003706A1 (fr) | 2000-01-27 |
| EP1096930A1 (fr) | 2001-05-09 |
| BR9912816A (pt) | 2001-05-08 |
| FR2781153A1 (fr) | 2000-01-21 |
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