ZA200006729B - Compounds of 12,13-(pyranosyl)-indolo(2,3-A)pyrrolo(3,4-C)carbazole and 12,13-(pyranosyl)-furo(3,4-C)indolo(2,3-A)carbazole, a process for their preparation and pharmaceutical compositions containing them. - Google Patents
Compounds of 12,13-(pyranosyl)-indolo(2,3-A)pyrrolo(3,4-C)carbazole and 12,13-(pyranosyl)-furo(3,4-C)indolo(2,3-A)carbazole, a process for their preparation and pharmaceutical compositions containing them.Info
- Publication number
- ZA200006729B ZA200006729B ZA200006729A ZA200006729A ZA200006729B ZA 200006729 B ZA200006729 B ZA 200006729B ZA 200006729 A ZA200006729 A ZA 200006729A ZA 200006729 A ZA200006729 A ZA 200006729A ZA 200006729 B ZA200006729 B ZA 200006729B
- Authority
- ZA
- South Africa
- Prior art keywords
- indolo
- carbazole
- alkyl
- nrarb
- aryl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9914433A FR2801054B1 (fr) | 1999-11-17 | 1999-11-17 | Nouveaux derives de 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo [3,4-c]carbazole et 12,13-(pyranosyl)-furo[3,4-c]indolo [2,3-a]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200006729B true ZA200006729B (en) | 2001-06-05 |
Family
ID=9552202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200006729A ZA200006729B (en) | 1999-11-17 | 2000-11-17 | Compounds of 12,13-(pyranosyl)-indolo(2,3-A)pyrrolo(3,4-C)carbazole and 12,13-(pyranosyl)-furo(3,4-C)indolo(2,3-A)carbazole, a process for their preparation and pharmaceutical compositions containing them. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6569858B2 (ja) |
EP (1) | EP1101770B1 (ja) |
JP (1) | JP3602050B2 (ja) |
KR (1) | KR100453980B1 (ja) |
CN (1) | CN1152040C (ja) |
AT (1) | ATE237625T1 (ja) |
AU (1) | AU771584B2 (ja) |
BR (1) | BR0005426A (ja) |
CA (1) | CA2325779C (ja) |
DE (1) | DE60002142T2 (ja) |
DK (1) | DK1101770T3 (ja) |
EA (1) | EA004737B1 (ja) |
ES (1) | ES2197061T3 (ja) |
FR (1) | FR2801054B1 (ja) |
HK (1) | HK1036991A1 (ja) |
HU (1) | HUP0004574A3 (ja) |
MX (1) | MXPA00010899A (ja) |
NO (1) | NO20005796L (ja) |
NZ (1) | NZ508231A (ja) |
PL (1) | PL343879A1 (ja) |
PT (1) | PT1101770E (ja) |
SI (1) | SI1101770T1 (ja) |
ZA (1) | ZA200006729B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
US6653290B2 (en) | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
RU2003131269A (ru) | 2001-03-22 | 2005-05-10 | Бристол-Маерс Сквибб Компани (Us) | Производные индолопирролокарбазолов и сахаров, цитотоксические и селективные по отношению к топоизомеразе i |
FR2826653B1 (fr) | 2001-06-29 | 2005-10-14 | Servier Lab | Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2831169B1 (fr) * | 2001-10-22 | 2003-12-12 | Servier Lab | Nouveaux derives d'hydroxyalkyle indolocarbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
ES2326459B1 (es) * | 2008-04-08 | 2010-05-28 | Universidad De Oviedo | Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos. |
CN104031052B (zh) * | 2014-05-20 | 2016-06-08 | 中国科学院南海海洋研究所 | 抗生素Indimicins A–E及其制备方法和在制备抗肿瘤药物中的应用 |
US10513515B2 (en) | 2017-08-25 | 2019-12-24 | Biotheryx, Inc. | Ether compounds and uses thereof |
EP3830093A1 (en) | 2018-07-27 | 2021-06-09 | Biotheryx, Inc. | Bifunctional compounds as cdk modulators |
RU2726801C1 (ru) * | 2019-10-16 | 2020-07-15 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Средство для терапии опухолей |
EP4143329A2 (en) | 2020-04-28 | 2023-03-08 | Anwita Biosciences, Inc. | Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015578A (en) * | 1989-03-23 | 1991-05-14 | Bristol-Myers Squibb Company | BMY-41950 antitumor antibiotic |
JPH05140168A (ja) * | 1991-11-13 | 1993-06-08 | Asahi Chem Ind Co Ltd | インドロカルバゾール誘導体及び該化合物を有効成分とする抗腫瘍剤 |
NZ245203A (en) * | 1991-11-29 | 1997-07-27 | Banyu Pharma Co Ltd | 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates |
JPH07112987A (ja) * | 1993-10-14 | 1995-05-02 | Asahi Chem Ind Co Ltd | スタウロスポリン糖部分変換誘導体 |
CO4940430A1 (es) * | 1997-07-07 | 2000-07-24 | Novartis Ag | Compuestos policiclicos que contienen estaurosporina hidrogenada con propiedades farmacologicas convenientes y un efecto inhibidor sobre el crecimiento de las celulas tumorales |
-
1999
- 1999-11-17 FR FR9914433A patent/FR2801054B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-07 MX MXPA00010899A patent/MXPA00010899A/es unknown
- 2000-11-09 DK DK00403107T patent/DK1101770T3/da active
- 2000-11-09 PT PT00403107T patent/PT1101770E/pt unknown
- 2000-11-09 ES ES00403107T patent/ES2197061T3/es not_active Expired - Lifetime
- 2000-11-09 EP EP00403107A patent/EP1101770B1/fr not_active Expired - Lifetime
- 2000-11-09 DE DE60002142T patent/DE60002142T2/de not_active Expired - Fee Related
- 2000-11-09 SI SI200030082T patent/SI1101770T1/xx unknown
- 2000-11-09 AT AT00403107T patent/ATE237625T1/de not_active IP Right Cessation
- 2000-11-14 JP JP2000346837A patent/JP3602050B2/ja not_active Expired - Fee Related
- 2000-11-15 PL PL00343879A patent/PL343879A1/xx not_active Application Discontinuation
- 2000-11-16 NZ NZ508231A patent/NZ508231A/en unknown
- 2000-11-16 NO NO20005796A patent/NO20005796L/no not_active Application Discontinuation
- 2000-11-16 EA EA200001078A patent/EA004737B1/ru unknown
- 2000-11-17 AU AU71681/00A patent/AU771584B2/en not_active Ceased
- 2000-11-17 CN CNB001285416A patent/CN1152040C/zh not_active Expired - Fee Related
- 2000-11-17 KR KR10-2000-0068432A patent/KR100453980B1/ko not_active IP Right Cessation
- 2000-11-17 HU HU0004574A patent/HUP0004574A3/hu unknown
- 2000-11-17 ZA ZA200006729A patent/ZA200006729B/xx unknown
- 2000-11-17 CA CA002325779A patent/CA2325779C/fr not_active Expired - Fee Related
- 2000-11-17 BR BR0005426-7A patent/BR0005426A/pt not_active Application Discontinuation
-
2001
- 2001-11-05 US US10/010,379 patent/US6569858B2/en not_active Expired - Fee Related
- 2001-11-08 HK HK01107825A patent/HK1036991A1/xx not_active IP Right Cessation
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