ZA200006642B - Hybrid polypeptides with enhanced pharmacokinetic properties. - Google Patents
Hybrid polypeptides with enhanced pharmacokinetic properties. Download PDFInfo
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- ZA200006642B ZA200006642B ZA200006642A ZA200006642A ZA200006642B ZA 200006642 B ZA200006642 B ZA 200006642B ZA 200006642 A ZA200006642 A ZA 200006642A ZA 200006642 A ZA200006642 A ZA 200006642A ZA 200006642 B ZA200006642 B ZA 200006642B
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- polypeptide
- core
- hybrid
- enhancer
- core polypeptide
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/082,279 US6258782B1 (en) | 1998-05-20 | 1998-05-20 | Hybrid polypeptides with enhanced pharmacokinetic properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200006642B true ZA200006642B (en) | 2001-05-28 |
Family
ID=22170199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200006642A ZA200006642B (en) | 1998-05-20 | 2000-11-15 | Hybrid polypeptides with enhanced pharmacokinetic properties. |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6258782B1 (fr) |
| EP (1) | EP1079846A4 (fr) |
| JP (1) | JP2002515449A (fr) |
| KR (1) | KR100742789B1 (fr) |
| CN (1) | CN1205995C (fr) |
| AU (1) | AU766995C (fr) |
| BR (1) | BR9910626A (fr) |
| CA (1) | CA2332338A1 (fr) |
| HK (1) | HK1039747A1 (fr) |
| HR (1) | HRP20000789A2 (fr) |
| HU (1) | HUP0101826A3 (fr) |
| ID (1) | ID29141A (fr) |
| IL (2) | IL139702A0 (fr) |
| MX (1) | MXPA00011314A (fr) |
| NO (1) | NO20005836L (fr) |
| NZ (1) | NZ508352A (fr) |
| PL (1) | PL344342A1 (fr) |
| RU (1) | RU2236865C2 (fr) |
| TR (1) | TR200100163T2 (fr) |
| WO (1) | WO1999059615A1 (fr) |
| YU (1) | YU71800A (fr) |
| ZA (1) | ZA200006642B (fr) |
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| US7118859B2 (en) * | 1996-01-17 | 2006-10-10 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| US6344545B1 (en) * | 1996-06-14 | 2002-02-05 | Progenics Pharmaceuticals, Inc. | Method for preventing HIV-1 infection of CD4+ cells |
| US7858298B1 (en) | 1996-04-01 | 2010-12-28 | Progenics Pharmaceuticals Inc. | Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists |
| US20040086528A1 (en) * | 1996-06-14 | 2004-05-06 | Progenics Pharmaceuticals, Inc. | Uses of a chemokine receptor for inhibiting HIV-1 infection |
| US6258782B1 (en) | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US6656906B1 (en) * | 1998-05-20 | 2003-12-02 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US20040228869A1 (en) * | 1998-12-16 | 2004-11-18 | Progenics Pharmaceuticals, Inc. | Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto |
| US20080015348A1 (en) * | 1998-12-16 | 2008-01-17 | Progenics Pharmaceuticals, Inc. | Nucleic acids encoding polypeptides of anti-CCR5 antibodies |
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1998
- 1998-05-20 US US09/082,279 patent/US6258782B1/en not_active Expired - Fee Related
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1999
- 1999-05-20 BR BR9910626-4A patent/BR9910626A/pt not_active Application Discontinuation
- 1999-05-20 NZ NZ508352A patent/NZ508352A/xx unknown
- 1999-05-20 YU YU71800A patent/YU71800A/sh unknown
- 1999-05-20 WO PCT/US1999/011219 patent/WO1999059615A1/fr not_active Application Discontinuation
- 1999-05-20 HU HU0101826A patent/HUP0101826A3/hu unknown
- 1999-05-20 JP JP2000549279A patent/JP2002515449A/ja active Pending
- 1999-05-20 IL IL13970299A patent/IL139702A0/xx active IP Right Grant
- 1999-05-20 KR KR1020007012887A patent/KR100742789B1/ko not_active IP Right Cessation
- 1999-05-20 US US09/315,304 patent/US6348568B1/en not_active Expired - Fee Related
- 1999-05-20 PL PL99344342A patent/PL344342A1/xx not_active Application Discontinuation
- 1999-05-20 AU AU41949/99A patent/AU766995C/en not_active Ceased
- 1999-05-20 ID IDW20002674A patent/ID29141A/id unknown
- 1999-05-20 EP EP99925716A patent/EP1079846A4/fr not_active Withdrawn
- 1999-05-20 CA CA002332338A patent/CA2332338A1/fr not_active Abandoned
- 1999-05-20 RU RU2000132227/15A patent/RU2236865C2/ru not_active IP Right Cessation
- 1999-05-20 MX MXPA00011314A patent/MXPA00011314A/es not_active IP Right Cessation
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- 1999-05-20 TR TR2001/00163T patent/TR200100163T2/xx unknown
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- 2000-11-15 IL IL139702A patent/IL139702A/en not_active IP Right Cessation
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2001
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2002
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| Publication number | Publication date |
|---|---|
| IL139702A (en) | 2007-10-31 |
| MXPA00011314A (es) | 2003-04-22 |
| AU4194999A (en) | 1999-12-06 |
| CN1310626A (zh) | 2001-08-29 |
| KR100742789B1 (ko) | 2007-07-25 |
| EP1079846A4 (fr) | 2003-01-02 |
| CA2332338A1 (fr) | 1999-11-25 |
| IL139702A0 (en) | 2002-02-10 |
| US6562787B1 (en) | 2003-05-13 |
| NZ508352A (en) | 2004-02-27 |
| PL344342A1 (en) | 2001-11-05 |
| RU2236865C2 (ru) | 2004-09-27 |
| HUP0101826A2 (hu) | 2001-09-28 |
| WO1999059615A9 (fr) | 2000-06-22 |
| TR200100163T2 (tr) | 2001-06-21 |
| AU766995C (en) | 2004-12-02 |
| HK1039747A1 (zh) | 2002-06-21 |
| HUP0101826A3 (en) | 2005-12-28 |
| WO1999059615A1 (fr) | 1999-11-25 |
| US6258782B1 (en) | 2001-07-10 |
| CN1205995C (zh) | 2005-06-15 |
| YU71800A (sh) | 2004-05-12 |
| US6348568B1 (en) | 2002-02-19 |
| HRP20000789A2 (en) | 2001-06-30 |
| NO20005836L (no) | 2001-01-19 |
| KR20010043681A (ko) | 2001-05-25 |
| AU766995B2 (en) | 2003-10-30 |
| ID29141A (id) | 2001-08-02 |
| BR9910626A (pt) | 2006-01-03 |
| JP2002515449A (ja) | 2002-05-28 |
| EP1079846A1 (fr) | 2001-03-07 |
| NO20005836D0 (no) | 2000-11-17 |
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