YU88901A - Derivati purina - Google Patents

Derivati purina

Info

Publication number
YU88901A
YU88901A YU88901A YUP88901A YU88901A YU 88901 A YU88901 A YU 88901A YU 88901 A YU88901 A YU 88901A YU P88901 A YUP88901 A YU P88901A YU 88901 A YU88901 A YU 88901A
Authority
YU
Yugoslavia
Prior art keywords
compounds
purine derivatives
preparation
adenosine
solvates
Prior art date
Application number
YU88901A
Other languages
English (en)
Inventor
Sandra Marina Monaghan
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU88901A publication Critical patent/YU88901A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)

Abstract

Ovaj pronalazak se odnosi na jedinjenja formule (I) i na njihove farmaceutski prihvatljive soli i solvate, na postupke za dobijanje intermedijera koji se koriste u njihovom dobijanju, i na preparate koji sadrže takva jedinjenja i na korišćenja takvih jedinjenja kao adenosin A2a receptor agonista.
YU88901A 1999-10-14 2000-10-06 Derivati purina YU88901A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9924363.6A GB9924363D0 (en) 1999-10-14 1999-10-14 Purine derivatives

Publications (1)

Publication Number Publication Date
YU88901A true YU88901A (sh) 2004-09-03

Family

ID=10862760

Family Applications (1)

Application Number Title Priority Date Filing Date
YU88901A YU88901A (sh) 1999-10-14 2000-10-06 Derivati purina

Country Status (50)

Country Link
US (1) US6350735B1 (sh)
EP (1) EP1220863B1 (sh)
JP (1) JP3994007B2 (sh)
KR (1) KR20020037774A (sh)
CN (1) CN1151167C (sh)
AP (1) AP1442A (sh)
AR (1) AR023275A1 (sh)
AT (1) ATE238336T1 (sh)
AU (1) AU768308B2 (sh)
BG (1) BG106569A (sh)
BR (1) BR0011776A (sh)
CA (1) CA2387531C (sh)
CO (1) CO5251399A1 (sh)
CR (1) CR6584A (sh)
CZ (1) CZ20021223A3 (sh)
DE (1) DE60002356T2 (sh)
DK (1) DK1220863T3 (sh)
DZ (1) DZ3159A1 (sh)
EA (1) EA004655B1 (sh)
EC (1) ECSP003712A (sh)
EE (1) EE200200193A (sh)
ES (1) ES2193990T3 (sh)
GB (1) GB9924363D0 (sh)
GE (1) GEP20043269B (sh)
GT (1) GT200000172A (sh)
HK (1) HK1047110B (sh)
HN (1) HN2000000204A (sh)
HU (1) HUP0203483A2 (sh)
IL (1) IL146342A0 (sh)
IS (1) IS6165A (sh)
MA (1) MA26828A1 (sh)
MX (1) MXPA02003812A (sh)
MY (1) MY136242A (sh)
NO (1) NO20021692D0 (sh)
NZ (1) NZ515323A (sh)
OA (1) OA12059A (sh)
PA (1) PA8503501A1 (sh)
PE (1) PE20010755A1 (sh)
PL (1) PL354932A1 (sh)
PT (1) PT1220863E (sh)
SI (1) SI1220863T1 (sh)
SK (1) SK4842002A3 (sh)
SV (1) SV2002000198A (sh)
TN (1) TNSN00202A1 (sh)
TR (1) TR200200985T2 (sh)
UA (1) UA66945C2 (sh)
UY (1) UY26397A1 (sh)
WO (1) WO2001027130A1 (sh)
YU (1) YU88901A (sh)
ZA (1) ZA200202849B (sh)

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AU2009203693B2 (en) 2008-01-11 2012-06-07 Novartis Ag Pyrimidines as kinase inhibitors
EP2391366B1 (en) 2009-01-29 2012-11-28 Novartis AG Substituted benzimidazoles for the treatment of astrocytomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EA201200260A1 (ru) 2009-08-12 2012-09-28 Новартис Аг Гетероциклические гидразоны и их применение для лечения рака и воспаления
EP2467141B1 (en) 2009-08-17 2018-10-31 Intellikine, LLC Heterocyclic compounds and uses thereof
EP2467383A1 (en) 2009-08-20 2012-06-27 Novartis AG Heterocyclic oxime compounds
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Also Published As

Publication number Publication date
ECSP003712A (es) 2002-05-23
GEP20043269B (en) 2004-06-25
CA2387531C (en) 2006-12-05
IS6165A (is) 2001-11-16
MA26828A1 (fr) 2004-12-20
CA2387531A1 (en) 2001-04-19
AU768308B2 (en) 2003-12-04
JP3994007B2 (ja) 2007-10-17
TR200200985T2 (tr) 2002-10-21
EE200200193A (et) 2003-06-16
CN1151167C (zh) 2004-05-26
PT1220863E (pt) 2003-07-31
UA66945C2 (uk) 2004-06-15
TNSN00202A1 (fr) 2005-11-10
CN1358192A (zh) 2002-07-10
AP1442A (en) 2005-06-29
ES2193990T3 (es) 2003-11-16
BR0011776A (pt) 2002-03-12
HUP0203483A2 (hu) 2003-02-28
IL146342A0 (en) 2002-07-25
US6350735B1 (en) 2002-02-26
GT200000172A (es) 2002-04-05
SK4842002A3 (en) 2003-06-03
ZA200202849B (en) 2003-06-25
AR023275A1 (es) 2002-09-04
SI1220863T1 (en) 2003-10-31
CR6584A (es) 2004-01-14
AP2002002478A0 (en) 2002-06-30
UY26397A1 (es) 2001-05-31
GB9924363D0 (en) 1999-12-15
JP2003511459A (ja) 2003-03-25
PA8503501A1 (es) 2002-02-21
DZ3159A1 (fr) 2001-04-19
PE20010755A1 (es) 2001-07-17
BG106569A (en) 2002-12-29
CO5251399A1 (es) 2003-02-28
OA12059A (en) 2006-05-03
HN2000000204A (es) 2001-06-21
KR20020037774A (ko) 2002-05-22
WO2001027130A1 (en) 2001-04-19
NZ515323A (en) 2003-10-31
DK1220863T3 (da) 2003-08-11
EA004655B1 (ru) 2004-06-24
NO20021692L (no) 2002-04-10
PL354932A1 (en) 2004-03-22
SV2002000198A (es) 2002-02-05
DE60002356T2 (de) 2004-02-19
HK1047110B (zh) 2005-03-04
EP1220863A1 (en) 2002-07-10
DE60002356D1 (de) 2003-05-28
MY136242A (en) 2008-08-29
HK1047110A1 (en) 2003-02-07
ATE238336T1 (de) 2003-05-15
MXPA02003812A (es) 2002-09-30
NO20021692D0 (no) 2002-04-10
EP1220863B1 (en) 2003-04-23
EA200101107A1 (ru) 2002-10-31
CZ20021223A3 (cs) 2003-05-14
AU7548800A (en) 2001-04-23

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