YU75401A - Polimorfni oblik soli maleinske kiseline 5-/4-/2-(n-metil- -(2-piridil)amino)etoksi/-benzil/tiazolidin-2,4-dion - Google Patents

Polimorfni oblik soli maleinske kiseline 5-/4-/2-(n-metil- -(2-piridil)amino)etoksi/-benzil/tiazolidin-2,4-dion

Info

Publication number
YU75401A
YU75401A YU75401A YUP75401A YU75401A YU 75401 A YU75401 A YU 75401A YU 75401 A YU75401 A YU 75401A YU P75401 A YUP75401 A YU P75401A YU 75401 A YU75401 A YU 75401A
Authority
YU
Yugoslavia
Prior art keywords
acid
ethoxy
benzyl
amino
methyl
Prior art date
Application number
YU75401A
Other languages
English (en)
Inventor
Paul David James Blackler
Robert Gordon Giles
Stephen Moore
Michael John Sasse
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9909471.6A external-priority patent/GB9909471D0/en
Priority claimed from GBGB9912195.6A external-priority patent/GB9912195D0/en
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of YU75401A publication Critical patent/YU75401A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Polimorfni oblik soli maleinske klseline i 5-[4-[2-(N-metil-N-(2-piridil)amino)etoksi]benzil]tizolidin-2,4-dion (Polimorf), koga karakterišu: (i) infracrveni spektar koji sadrži pikove 1752, 1546, 1154, 621 i 602 cm-1; i/ili (ii) Raman-ov spektar koji sadrži pikove 1751, 1243 i 602 cm-1; i/ili (lil) spektar nuklearne magnetne rezonance čvrste faze, koji sadrži pikove 111,0, 113,6, 119,8, 129,1, 130,9, 131,8, 134,7, 138,7, 146,5, 152,7, 157,5, 169,6, 171,0, 178,7 ppm; i/ili (iv) spektar difrakcije X-zraka praha (XRPD) koji daje izračunata rastojanja rešetke 0,587, 0,530, 0,469, 0,409, 0,388, 0,361, 0,353 i 0,346 nm; postupak za dobijanje tog jedinjenja, farmaceutski preparat koji sadrži to jedinjenje i upotrebu tog jedinjenja u medicini.
YU75401A 1999-04-23 2000-04-19 Polimorfni oblik soli maleinske kiseline 5-/4-/2-(n-metil- -(2-piridil)amino)etoksi/-benzil/tiazolidin-2,4-dion YU75401A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909471.6A GB9909471D0 (en) 1999-04-23 1999-04-23 Novel compounds
GBGB9912195.6A GB9912195D0 (en) 1999-05-25 1999-05-25 Novel pharmaceutical

Publications (1)

Publication Number Publication Date
YU75401A true YU75401A (sh) 2004-09-03

Family

ID=26315459

Family Applications (1)

Application Number Title Priority Date Filing Date
YU75401A YU75401A (sh) 1999-04-23 2000-04-19 Polimorfni oblik soli maleinske kiseline 5-/4-/2-(n-metil- -(2-piridil)amino)etoksi/-benzil/tiazolidin-2,4-dion

Country Status (36)

Country Link
EP (2) EP1277753A1 (sh)
JP (1) JP2002543076A (sh)
KR (1) KR100744361B1 (sh)
CN (1) CN1152878C (sh)
AP (1) AP1607A (sh)
AR (2) AR023750A1 (sh)
AU (2) AU4307200A (sh)
BG (1) BG65517B1 (sh)
BR (1) BR0009935A (sh)
CA (1) CA2370262A1 (sh)
CO (1) CO5170419A1 (sh)
CZ (1) CZ20013801A3 (sh)
DZ (1) DZ3164A1 (sh)
EA (1) EA003031B1 (sh)
EG (1) EG23937A (sh)
GC (1) GC0000250A (sh)
HK (1) HK1045152A1 (sh)
HR (1) HRP20010774A2 (sh)
HU (1) HUP0200937A3 (sh)
IL (1) IL146115A0 (sh)
MA (1) MA26786A1 (sh)
MX (1) MXPA01010822A (sh)
MY (1) MY138673A (sh)
NO (1) NO320587B1 (sh)
NZ (1) NZ515167A (sh)
OA (1) OA11873A (sh)
PE (1) PE20010045A1 (sh)
PL (1) PL351685A1 (sh)
SK (1) SK14932001A3 (sh)
TR (1) TR200103060T2 (sh)
TW (1) TWI288749B (sh)
UA (1) UA67845C2 (sh)
UY (1) UY26119A1 (sh)
WO (1) WO2000064893A2 (sh)
YU (1) YU75401A (sh)
ZA (1) ZA200108718B (sh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726568D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
CA2369200A1 (en) * 1999-04-13 2000-10-19 Peter L. Collins Production of attenuated chimeric respiratory syncytial virus vaccines from cloned nucleotide sequences
AU765005B2 (en) 1999-04-23 2003-09-04 Smithkline Beecham Plc Polymorph of 5-(4-(2- (N-methyl-N-( 2-pyridyl)amino) ethoxy)benzyl) thiazolidine-2,4-dione, maleic acid salt
PL351686A1 (en) 1999-04-23 2003-06-02 Smithkline Beecham Plc Novel pharmaceutical
GB0006133D0 (en) 2000-03-14 2000-05-03 Smithkline Beecham Plc Novel pharmaceutical
US7241895B2 (en) * 2000-09-26 2007-07-10 Dr. Reddy's Laboratories Limited Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
WO2004062667A1 (en) * 2003-01-08 2004-07-29 Dr. Reddy's Laboratories Limited Amorphous form of rosiglitazone maleate and process for preparation thereof
GB0307259D0 (en) * 2003-03-28 2003-05-07 Glaxo Group Ltd Process
EP1468997A3 (en) * 2003-04-18 2004-11-03 CHEMI S.p.A. Polymorphous forms of rosiglitazone maleate
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
ITMI20041537A1 (it) * 2004-07-28 2004-10-28 Chemi Spa Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
TW201336497A (zh) * 2007-02-08 2013-09-16 Daiichi Sankyo Co Ltd 噻唑啶二酮化合物之結晶型及其製法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB9726568D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
PE20010045A1 (es) 2001-03-10
CA2370262A1 (en) 2000-11-02
MA26786A1 (fr) 2004-12-20
WO2000064893A3 (en) 2001-01-25
HUP0200937A3 (en) 2004-03-29
BG106122A (en) 2002-05-31
KR100744361B1 (ko) 2007-07-30
BG65517B1 (bg) 2008-10-31
AP2001002329A0 (en) 2001-12-31
NZ515167A (en) 2004-02-27
NO20015148L (no) 2001-12-17
AR023560A1 (es) 2002-09-04
MY138673A (en) 2009-07-31
EP1277753A1 (en) 2003-01-22
AU4307200A (en) 2000-11-10
UY26119A1 (es) 2000-12-29
KR20010110804A (ko) 2001-12-13
NO320587B1 (no) 2005-12-27
TR200103060T2 (tr) 2002-05-21
EP1175418A2 (en) 2002-01-30
EG23937A (en) 2008-01-14
IL146115A0 (en) 2002-07-25
EA200101122A1 (ru) 2002-04-25
OA11873A (en) 2006-03-27
AU2755102A (en) 2002-05-16
TWI288749B (en) 2007-10-21
CO5170419A1 (es) 2002-06-27
EA003031B1 (ru) 2002-12-26
ZA200108718B (en) 2002-12-03
AR023750A1 (es) 2002-09-04
CN1355800A (zh) 2002-06-26
MXPA01010822A (es) 2002-06-04
GC0000250A (en) 2006-11-01
DZ3164A1 (fr) 2000-11-02
CN1152878C (zh) 2004-06-09
JP2002543076A (ja) 2002-12-17
HUP0200937A2 (en) 2002-08-28
WO2000064893A2 (en) 2000-11-02
HK1045152A1 (zh) 2002-11-15
CZ20013801A3 (cs) 2002-07-17
AP1607A (en) 2006-05-03
AU771342B2 (en) 2004-03-18
HRP20010774A2 (en) 2002-10-31
NO20015148D0 (no) 2001-10-22
BR0009935A (pt) 2002-04-16
PL351685A1 (en) 2003-06-02
UA67845C2 (uk) 2004-07-15
SK14932001A3 (sk) 2002-02-05

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