YU68600A - Upotreba hemopreventivnog agensa u proizvodnji farmaceutskog preparata za upotrebu u prevenciji karcinogeneze prostate - Google Patents

Upotreba hemopreventivnog agensa u proizvodnji farmaceutskog preparata za upotrebu u prevenciji karcinogeneze prostate

Info

Publication number
YU68600A
YU68600A YU68600A YU68600A YU68600A YU 68600 A YU68600 A YU 68600A YU 68600 A YU68600 A YU 68600A YU 68600 A YU68600 A YU 68600A YU 68600 A YU68600 A YU 68600A
Authority
YU
Yugoslavia
Prior art keywords
prostate
prostate cancer
chemopreventive agent
cancerogenesis
prevention
Prior art date
Application number
YU68600A
Other languages
English (en)
Inventor
Mitchell S. Steiner
Sharon Raghow
Original Assignee
The University Of Tennessee Research Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Tennessee Research Corporation filed Critical The University Of Tennessee Research Corporation
Publication of YU68600A publication Critical patent/YU68600A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Pronalazak obezbeduje upotrebu hemopreventivnog agensa, posebno toremifena i njegovih analoga ili metabolita, u proizvodnji farmaceutskog preparata za upotrebu radi prevencije, sprečavanja recidiva, suzbijanja ili inhibicije razvoja kancerogeneze prostate. Farmaceutski preparat proizveden upotrebom označenog hemopreventivnog agensa obezbedjuje bezbedno i efektivno suzbijanje ili inhibiciju latentnog kancera prostate i posebno je koristan kada se primenjuje na subjekte koji imaju povišen rizik od razvoja kancera prostate, na primer one koji imaju benignu hiperplaziju prostate, intraepitelijalnu neoplaziju prostate (PIN), ili abnormalno visoki nivo cirkulišućeg prostata-specifičnog antitela (PSA), ili onih koji imaju porodičnu istoriju kancera prostate.[This invention provides the chemoprevention of prostate cancer and, more particularly, to a method of administering to a subject an effective dose of a chemopreventive agent, toremifene and analogs or metabolites thereof, to prevent recurrence of, suppress or inhibit prostate carcinogenesis. The present invention provides a safe and effective method for suppressing or inhibiting latent prostate cancer and is particularly useful for treating subjects having an elevated risk of developing prostate cancer, for example, those having benign prostatic hyperplasia, prostate intraepithelial neoplasia (PIN), or an abnormally high level of circulating prostate specific antibody (PSA), or who have a family history of prostate cancer.
YU68600A 1998-05-07 1999-05-07 Upotreba hemopreventivnog agensa u proizvodnji farmaceutskog preparata za upotrebu u prevenciji karcinogeneze prostate YU68600A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8460298P 1998-05-07 1998-05-07

Publications (1)

Publication Number Publication Date
YU68600A true YU68600A (sh) 2003-12-31

Family

ID=22186034

Family Applications (1)

Application Number Title Priority Date Filing Date
YU68600A YU68600A (sh) 1998-05-07 1999-05-07 Upotreba hemopreventivnog agensa u proizvodnji farmaceutskog preparata za upotrebu u prevenciji karcinogeneze prostate

Country Status (26)

Country Link
US (1) US6265448B1 (sh)
EP (3) EP1003496B1 (sh)
JP (2) JP4482229B2 (sh)
AT (1) ATE283043T1 (sh)
AU (1) AU761435B2 (sh)
BG (1) BG65597B1 (sh)
CA (1) CA2323809C (sh)
CZ (1) CZ300960B6 (sh)
DE (2) DE69922131T2 (sh)
DK (1) DK1003496T3 (sh)
EA (1) EA003466B1 (sh)
ES (1) ES2145730T3 (sh)
HR (1) HRP20000729A2 (sh)
HU (1) HUP0102068A3 (sh)
IL (3) IL138437A0 (sh)
IS (2) IS2213B (sh)
NO (1) NO20005625L (sh)
NZ (1) NZ527522A (sh)
PL (1) PL207462B1 (sh)
PT (1) PT1003496E (sh)
SI (1) SI1003496T1 (sh)
SK (1) SK16642000A3 (sh)
TR (1) TR200003269T2 (sh)
UA (1) UA74532C2 (sh)
WO (1) WO1999056739A1 (sh)
YU (1) YU68600A (sh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
DE69922131T2 (de) * 1998-05-07 2005-11-24 The University Of Tennessee Research Corp., Knoxville Medikament zur behandlung intraepithelialer prostataneoplasie
US20030130316A1 (en) * 2000-03-20 2003-07-10 Steiner Mitchell S. Method for chemoprevention of prostate cancer
US6413534B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
US20040092602A1 (en) * 1998-05-07 2004-05-13 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
US20040176470A1 (en) * 1998-05-07 2004-09-09 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
WO2001017480A2 (en) * 1999-09-09 2001-03-15 Androsolutions, Inc. Methods and compositions for preventing and treating urinary tract disorders
US6642274B1 (en) 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
US20050080143A1 (en) * 2001-11-29 2005-04-14 Steiner Mitchell S. Treatment of androgen-deprivation induced osteoporosis
US20040096510A1 (en) * 2001-11-29 2004-05-20 Steiner Mitchell S. Prevention and treatment of androgen-deprivation induced osteoporosis
US20040214898A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20040213841A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S Methods for treating hot flashes and gynecomastia
ES2319785T3 (es) 2001-11-29 2009-05-12 Gtx, Inc. Prevencion y tratamiento de osteoporosis inducida por privacion de androgenos.
US20070197664A1 (en) * 2001-11-29 2007-08-23 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US7524866B2 (en) * 2001-11-29 2009-04-28 Gtx, Inc. Prevention and treatment of androgen—deprivation induced osteoporosis
US7332525B2 (en) * 2003-01-17 2008-02-19 Castle Erik P Method of treatment of prostate cancer and composition for treatment thereof
US7070816B2 (en) * 2003-12-05 2006-07-04 New Chapter, Inc. Methods for treating prostatic intraepithelial neoplasia with herbal compositions
US20050208159A1 (en) * 2004-03-16 2005-09-22 Kang Kyung S Phytoestrogenic composition comprising an extract of chinese licorice root, liquiritin or isoliquiritin
US20060019989A1 (en) * 2004-07-21 2006-01-26 Steiner Mitchell S Compositions comprising 5-alpha reductase inhibitors and SERMs and methods of use thereof
US20060105045A1 (en) * 2004-11-08 2006-05-18 Buchanan Charles M Cyclodextrin solubilizers for liquid and semi-solid formulations
US20060105992A1 (en) * 2004-11-08 2006-05-18 Buchanan Charles M Pharmaceutical formulations of cyclodextrins and selective estrogen receptor modulator compounds
US20060270641A1 (en) * 2005-05-31 2006-11-30 Steiner Mitchell S Method for chemoprevention of prostate cancer
USD969722S1 (en) 2021-09-28 2022-11-15 Wagner Delima Stabilizing wedge pad

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US4474813A (en) 1980-10-24 1984-10-02 Schering Corporation Pharmaceutical preparations comprising flutamide
FI77839C (fi) 1982-05-27 1989-05-10 Farmos Oy Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat.
GB2126576B (en) * 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
US5491173A (en) 1982-06-25 1996-02-13 Orion-Yhtyma Oy Tri-phenyl alkene derivatives and their preparation and use
US5595985A (en) 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
US4990538A (en) 1989-08-23 1991-02-05 Harris Adrian L Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs
GB9126209D0 (en) 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
GB9207437D0 (en) 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
AU687767B2 (en) * 1992-12-01 1998-03-05 Oy Biotie Therapies Ltd Syndecan stimulation of cellular differentiation
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
JPH08510451A (ja) 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
CZ285508B6 (cs) 1993-08-09 1999-08-11 Edward Baral Použití trifenylethylenových antiestrogenů pro zvyšování citlivosti rakovinných buněk k lyzi zprostředkované zabíječskými buňkami
US5650425A (en) * 1994-04-04 1997-07-22 Pharmos Corporation Permanently ionic derivatives of steroid hormones and their antagonists
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DE69922131T2 (de) * 1998-05-07 2005-11-24 The University Of Tennessee Research Corp., Knoxville Medikament zur behandlung intraepithelialer prostataneoplasie

Also Published As

Publication number Publication date
JP2002513755A (ja) 2002-05-14
DE69922131T2 (de) 2005-11-24
IL138437A (en) 2008-12-29
EA003466B1 (ru) 2003-06-26
CA2323809C (en) 2007-09-18
TR200003269T2 (tr) 2001-02-21
CZ300960B6 (cs) 2009-09-23
EP1003496A1 (en) 2000-05-31
JP2008163048A (ja) 2008-07-17
PT1003496E (pt) 2005-04-29
US6265448B1 (en) 2001-07-24
ES2145730T3 (es) 2005-06-16
EP1475087A2 (en) 2004-11-10
NO20005625D0 (no) 2000-11-07
SK16642000A3 (sk) 2002-08-06
EP1003496B1 (en) 2004-11-24
AU4072699A (en) 1999-11-23
BG65597B1 (bg) 2009-02-27
DE1003496T1 (de) 2000-11-02
IL138437A0 (en) 2001-10-31
HUP0102068A3 (en) 2002-11-28
EP2277514A1 (en) 2011-01-26
ATE283043T1 (de) 2004-12-15
UA74532C2 (en) 2006-01-16
CA2323809A1 (en) 1999-11-11
EP1475087A3 (en) 2007-07-11
HUP0102068A2 (hu) 2002-05-29
IS5700A (is) 2000-11-01
EA200000100A1 (ru) 2000-08-28
NO20005625L (no) 2001-01-05
IL193231A0 (en) 2009-02-11
CZ20004118A3 (cs) 2002-07-17
JP4482229B2 (ja) 2010-06-16
WO1999056739A1 (en) 1999-11-11
DE69922131D1 (de) 2004-12-30
NZ527522A (en) 2005-04-29
SI1003496T1 (en) 2005-10-31
IS2213B (is) 2007-03-15
HRP20000729A2 (en) 2001-06-30
IS8354A (is) 2006-03-15
PL344000A1 (en) 2001-09-10
AU761435B2 (en) 2003-06-05
ES2145730T1 (es) 2000-07-16
PL207462B1 (pl) 2010-12-31
BG105022A (bg) 2001-07-31
DK1003496T3 (da) 2005-04-04

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